In one aspect, the invention relates to a method suitable for administering protein therapeutic molecules orally, sublingually, topically, intravenously, subcutaneously, nasally, vaginally, rectally or by inhalation so as to avoid inactivation, by using VHH polypeptides derived from Camelidae antibodies. The invention further relates to the said therapeutic molecules. The invention further a method for delivering therapeutic molecules to the interior of cells. The invention further relates to anti-IgE therapeutic molecules. In one aspect, the present invention relates to a method wherein an immunoglobulin single variable domain (such as a Nanobody) and/or construct thereof are absorbed in pulmonary tissue. More particularly, the invention provides systemic delivery of an immunoglobulin single variable domain and/or construct thereof via the pulmonary route.

The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure teaches a condensation nicotine aerosol where nicotine meta-salicylate is vaporized. This disclosure relates to aerosol nicotine delivery devices. The delivery devices can be activated by actuation mechanisms to vaporize thin films comprising a nicotine meta-salicylate. More particularly, this disclosure relates to thin films of nicotine salt with meta salicylic acid for the treatment of nicotine craving and for effecting smoking cessation.

The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutics agents to patients.

A nasal delivery device for and a method of delivering a substance to a nasal cavity of a subject, the delivery device comprising: a delivery unit for delivering a flow entraining a substance to one nostril of a subject, the delivery unit including a nosepiece for fitting to a nostril of the subject; and a flow resistor unit for fitting to the other nostril of the subject, the flow resistor unit including a progressive resistor for progressively providing an increasing flow resistance to the delivered flow.

An improved medicant delivery system is disclosed wherein the carrier for the medicant is a fluid that can be atomized or vaporized by exposure to heat. The system provides for repeatable dose of medicant, can be stored in any orientation, and/or has an ability to maximize energy efficiency.

The invention relates to a control device (10) for a medical aerosol delivery device (2), a medical aerosol delivery system, a method for controlling a medical aerosol delivery device (2), a computer program element for controlling such device or system, and a computer readable medium having stored such computer program element. The control device is configured to provide inhalation length data and to select an aerosol delivery mode from at least a first aerosol delivery mode or a different, second aerosol delivery mode based on the provided inhalation length data. The first aerosol delivery mode and the different, second aerosol delivery mode are one of a target inhalation mode, a tidal breathing mode, a continuous aerosol delivery mode and breath-actuated delivery mode. Optionally, the control device (10) comprises a provision unit (11) and a control unit (13). The provision unit (11) is configured to provide inhalation length data. The processing unit may be configured to select either a first aerosol delivery mode or a different, second aerosol delivery mode based on the provided inhalation length data. The medical aerosol delivery system comprises an aerosol delivery device (2) and such control device (10). The control device (10) is configured to control the aerosol delivery device (2). The aerosol delivery device (2) is configured to deliver aerosol to a user.

The invention relates a metering device for fluids from a containment volume. The metering device is a means to dispense metered volumes of fluids such as detergents, medicaments, lotions and the like. The invention further provides a container for fluid material to be dispensed in metered doses.

A drug solution tank of the present invention is a drug solution tank for an ultrasonic inhaler, including a drug solution reservoir portion having an upper edge that surrounds an opening and a bottom portion formed so as to protrude downward, a flange portion formed so as to extend outward from the upper edge of the drug solution reservoir portion, and a leg portion that is continuous with the outer perimeter or lower surface of the flange portion, is formed so as to surround the drug solution reservoir portion, and extends downward past the bottom portion of the drug solution reservoir portion.

In a method and in an apparatus for the controlled delivery of particles, said particles are supplied to a measurement station in which the quantity of particles is detected. The particles are subsequently transferred by the measurement station to a dispensing device and are dispensed.

A fluid dispenser device having a reservoir; a valve; a cocking member movable between rest and primed positions and between primed and dispensing positions, the cocking member includes a set of teeth; a blocking device blocking the cocking member in the primed position; a trigger system controlled by inhaling to release the blocking device; a reservoir support element including a cam opening; and a meshing wheel having a toothed projection co-operating with the set of teeth and a cam projection co-operating with the cam opening. The toothed projection is centered relative to the wheel rotation axis, and the cam projection is offset relative to the axis. The meshing wheel completes a turn when the cocking member moves from its primed towards its dispensing position, such that the cam projection causes the reservoir support element to perform reciprocating axial movement for actuating and returning the valve into its rest position.