Methods and vaporizer apparatuses that estimate, measure and/or predict the amount of vapor and/or material (including active ingredients) released by the vaporizer apparatus. In particular, described herein are electronic vaporizers and methods of using them that determine a dose/amount of vapor and/or a material in the vapor based primarily or exclusively on the electrical and thermal properties, e.g., power or energy applied to the vaporizing element (e.g., heating coil) and the temperature of the material immediately before and as it is vaporized. Dose information may be used to control operation of the device and/or reported to the user.

A sensing module for monitoring dosage delivery of a vaporized material, and a portable vaporization unit including the sensing module, include a light sensor that detects disruptions in a light path across a vapor channel, the disruptions caused by the vaporized material flowing through the vapor channel. The light sensor includes a UV light source, which may emit 370 nm wavelength light, and a UV light detector that converts intensity of incident light in the light path into a signal. A microprocessor of the sensing module compares the signal to a baseline measurement to determine the concentration of a medicament in the vapor; then, using the flow rate and activation time of the device, the microprocessor determines the dosage and can perform monitoring and reporting actions based on the dosage. A measuring circuit measures fluctuations in resistance/impedance of a vaporization element to further determine flow rate and/or dosage.

Systems and methods of an electronic drug delivery system for use in a treatment program (e.g., a smoking cessation program). The delivery system can include a mobile platform and a hand-held inhalation delivery device having a controller circuit coupled to a power source, sensors, aerosolizer drivers, and a rescue button, and a pod removably coupled to the delivery device. The delivery system generates an aerosol mixture from substances in the pod in accordance with the treatment program, and delivers the aerosol mixture for inhalation by a user. The controller circuit individually and dynamically controls the aerosolizer drivers to generate signals that drive a plurality of thermal, or non-thermal, aerosolizers of the pod to generate individually tailored aerosol mixtures from multiple substances in the aerosolizer pod. The generated aerosol mixtures can have various percentages of the substances, and have different aerosol droplet sizes during different portions of the treatment program.

An aerosol provision system includes one or more receptacles each forming a respective central space, a base adapted to support the or each receptacle, the or each receptacle being removable from the base and at least a first airflow generator, operable to draw air through at least a first aerosol generator, wherein the base includes one or more outlets through which, in operation, aerosolized payload is directed to flow from the base into the central space of a respective receptacle and the or each receptacle comprises a first opening through which the user can inhale the aerosolized payload.

The present disclosure provides a method for the surface modification of microstructured components having a polar surface, in particular for high-pressure applications. According to the method, a microstructured component is contacted, in particular treated, with a modification reagent, wherein the surface properties of the component are modified by chemical and/or physical interaction of the component surface and of the modification reagent.

The accessory (110) for an inhaler (100) is adapted to be removably assembled on a casing (101) of the inhaler (100), and comprises: an acceleration sensor (112), an optical type proximity sensor (113), an electronic circuitry (114) electrically connected to the acceleration sensor (112) and to the proximity sensor (113); the electronic circuitry (114) in combination with the acceleration sensor (112) and the proximity sensor (113) is adapted to detect a drug administration process; the electronic circuitry (114) in combination with the acceleration sensor (112) is adapted to detect an inhalation flow inside said inhaler (100).

A powder inhaler assembly includes a powder inhaler including a metering device having a dosing recess and movable, with respect to a container and to an inhalation channel, between an idle state, in which the dosing recess is in communication with an opening of the container so as to be filled with a dose of the powdered medicament, and a triggered state, in which the dosing recess is in communication with the inhalation channel for enabling inhalation of a dose of the powdered medicament contained in the dosing recess through a mouthpiece. An electronic module is attachable to the powder inhaler and includes a non-contact sensor positioned and configured to sense position(s) of at least part of the metering device to detect at least when the metering device is in the triggered state.

Pre-connected analyte sensors are provided. A pre-connected analyte sensor includes a sensor carrier attached to an analyte sensor. The sensor carrier includes a substrate configured for mechanical coupling of the sensor to testing, calibration, or wearable equipment. The sensor carrier also includes conductive contacts for electrically coupling sensor electrodes to the testing, calibration, or wearable equipment.

The invention relates to the field of inhalation methods and inhalation devices for liquids. In particular, the invention relates to an inhalation method using an inhalation device adapted to separately eject at least two liquid compositions each having different properties, and to a method for the generation of an aerosol of at least two medicinal formulations by means of such inhalation device.

The present invention provides for a method for the treatment of a respiratory disease, disorder or condition, or a viral infection or viral disease, disorder or condition in a subject, the method comprising the step of administering to said subject a medically active liquid in nebulized form by inhalation, wherein the medically active liquid comprises niclosamide or a pharmaceutically acceptable salt thereof and wherein the medically active liquid is administered in nebulized form using an inhalation device.