An ultrasonic vaporization assembly includes: a piezoelectric drive element provided with a first through hole; a vaporizer plate stacked with the piezoelectric drive element, the vaporizer plate having a microporous zone at a position corresponding to the first through hole; and a loading board arranged on a side surface of the vaporizer plate which faces away from the piezoelectric drive element, the loading board being provided with a second through hole at a position corresponding to the microporous zone. A ratio of a pore size of the second through hole to a diameter of the microporous zone is greater than or equal to 0.75 and less than or equal to 1.5.

Disclosed herein is a nebulizer comprising of a medicine cup reservoir containing an aqueous pirfenidone solution a medicine cup reservoir cap, an aerosol generator, an aerosol mixing chamber to which freshly generated aerosol resides until inhaled, a one-way inhalation valve, a mouthpiece and a one-way exhalation valve. The invention allows atmospheric pressure to be maintained inside the medicine cup reservoir during nebulization and optimizes the volume of the aerosol mixing chamber to minimize freshly generated aerosol inter-droplet collision, impaction of aerosol to the aerosol mixing chamber wall, droplet growth and/or condensation during exhalation, prior to inhalation, or during inhalation. The larger aerosol mixing chamber volume also allows the aerosol to accumulate during the exhalation phase. Despite venting producing a larger generated aerosol droplet population mean compared to the non-vented aerosol generator, The combined effect of the invention increases device output rate of respirable aerosol droplets, increases pirfenidone Cmax and AUC to improve treatment or prevention of various diseases, including disease associated with the lung, heart and kidney, including fibrosis, inflammatory conditions and transplant rejection.

An aerosol generating device includes an aerosol generator and a plug. The aerosol generator includes a container and an atomizing module arranged in the container. The container has a liquid chamber, an aerosol chamber, and an insertion slot defining an insertion direction. The liquid chamber and the aerosol chamber are respectively arranged at two opposite sides of the atomizing module, and are in spatial communication with each other through the atomizing module. The atomizing module includes two electrode regions having the same polarity and being electrically connected to each other. The plug is detachably inserted into the insertion slot of the container along the insertion direction, and a conductive terminal of the plug contacts the two electrode regions.

An ultrasonic nebulizer includes a tank unit configured to be detachable with respect to a main body. The tank unit includes a working tank in which an ultrasonic vibrator is incorporated, a medicine tank, and a medicine tank cover, which are arranged overlaid in the stated order. The output of an oscillation circuit in the main body is applied to the ultrasonic vibrator through a main body-side contact electrode and a tank-side contact electrode when the tank unit is mounted on the main body. The main body includes an air fan that blows air into the medicine tank through an air duct of the medicine tank cover, and a medicine tank cover detection unit that detects whether or not the air duct of the medicine tank cover is adjacent to the main body so as to detect whether or not the tank unit is mounted on the main body.

It is a support mask with a mounting strip to the head of the user. Inside the mask, the actuating mask is fixed with its vapor inlet tube connected, removable, with the injector tube of an external receptacle where a micro compact removable nebulizer is set up. The micro nebulizer has a micro ultrasonic cavitation microsystem capable of generating the vibrations necessary to vaporize the medicated liquid contained in a built-up tank. That ultrasonic mechanism is activated by a small electronic device with an activation button that is housed in a side enclosed area and is powered by batteries inside a similar battery enclosed area on the opposite side. The external surface of said support mask, presents, in strategic places, fixation means to enable an external party face mask of a laminar material molded similar to those characters admired by children.

A microporous vaporization assembly includes: a microporous vaporization plate for vaporizing an aerosol-generation substrate to generate aerosols; and a circuit board flexibly electrically connected to the microporous vaporization plate, the circuit board transmitting an electrical signal of the circuit board to the microporous vaporization plate. In an embodiment, the microporous vaporization assembly includes a flexible electrical conductor between the circuit board and the microporous vaporization plate. The flexible electrical conductor is in contact with the circuit board and the microporous vaporization plate respectively, to implement a flexible electrical connection between the circuit board and the microporous vaporization plate.

A nebulizer assembly for a respiratory device is provided having a housing defining a chamber. The housing also has a nebulizer port configured to receive a nebulizer to discharge atomized medication into the chamber. An outlet of a handle is coupled to the inlet of the housing. A hose is coupled to an inlet of the handle. A patient interface is coupled to the outlet of the housing. Air flows from the hose to the patient interface via the handle and the housing. The air mixes with the atomized medication within the chamber.

The present invention provides for the integration of drug dispersion methods into a drug or medicine delivery system. The drug dispersion methods used include shear (e.g., air across a drug, with or without a gas assist), capillary flow or a venturi effect, mechanical means such as spinning, vibration, or impaction, and turbulence (e.g., using mesh screens, or restrictions in the air path). These methods of drug dispersion allow for all of the drug in the system to be released, allowing control of the dosage size. These methods also provide for drug metering, fluidization, entrainment, deaggragation and deagglomeration. The present invention also provides for the integration of a drug sealing system into the device. The drug sealing system provides a way of blocking the migration of drug from one area of the package to another. The drug seal system can also provide a method of tightly containing the drug until the package is opened, of directing airflow through the package and of managing and containing the drug during the package/device manufacturing process.

A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.

A flavored vapor generator (100, 200, 300, 400) used for an electronic smoking apparatus (10) comprises a housing; a liquid retention material (155, 255) which is filled, soaked or immersed with a flavored liquid and received inside the housing; an electric heater (150, 350, 450) for heating the liquid retention material (155, 255) to generate flavored vapor; and a sensor (156, 356, 456) for monitoring soaking or wetness conditions of the liquid retention material (155, 255) and providing signals for determining whether the flavored liquid in the liquid retention material (155, 255) is exhausted or almost exhausted.