A portable, handheld measurement device for monitoring lung function is provided. The measurement device includes one or more components designed to directly or indirectly detect air flow properties such as the direction, flow rate, and/or volume of air flow within a lumen of the device. In some embodiments, the air flow properties are determined from changes in pressure within the lumen. The measurement device may form part of a system that includes a remote computing device and a computer server. In some such embodiments, at least one of the computers present within the system calculates spirometry measurements from the air flow detected within the measurement device. Such measurements may be stored, displayed, and/or shared with others. Various methods performed by the devices and systems are also disclosed.

Methods and devices for delivering a dose, such as a medicament, for inhalation. A dose may be stored by a delivery device and dispersed and delivered in a metered fashion to a subject, such as by the subject inhaling via a mouthpiece of the delivery device. One or more chambers of the device may have a toroidal shape and may be arranged to be selectively opened for fluid communication with a flow path of the delivery device, such as by sliding the chamber relative to a portion of the flow path. The flow path may include a restriction that permits air to bypass the chamber, and/or the chamber may be arranged so that fluid entering the chamber interacts with fluid exiting the chamber so as to enhance dispersion of the dose.

An example aerosol delivery device includes a mouthpiece having an airflow outlet, and an airflow passage extending between an airflow inlet and the airflow outlet. The example aerosol delivery device further includes a housing configured to receive a cartridge that includes an aerosolizable substance and a vapor element configured to heat the aerosolizable substance, and an internal power source configured to provide electrical power. The example aerosol delivery device further includes a controller coupled to the internal power source to receive a portion of the electrical power and configured to, when the cartridge is installed at the housing, cause the vapor element of the cartridge to heat the aerosolizable substance to release an aerosol into the airflow passage during an inhalation through the airflow outlet, and a connector configured to receive power from an external source to recharge the internal power source.

A medication delivery system including a holding chamber having an input and an output end, a backpiece coupled to the input end of the holding chamber and having an electrical circuit and an opening. An MDI includes an insert portion moveable between an engaged position wherein the insert portion is received in the opening and a disengaged position wherein the insert portion is removed from the opening, and at least one contact that completes the electrical circuit when the insert portion is in the engaged position.

The invention relates to a valveless spacer device for a metered dose inhaler (MDI), the spacer device comprising a body having an inlet and an outlet opposed from the inlet, a demountable, flexible bag attached to the body, the bag and body together defining a chamber, such that the inlet and outlet are in fluid flow communication with an interior of the chamber, wherein the inlet is configured to be connected to an MDI containing a drug to be inhaled and wherein the flexible bag, following actuation of the MDI, serves as a reservoir allowing for the formation of a cloud or mist of the drug therewithin which is then ready for inhalation, the flexible bag being configured to be at least partially deflatable and at least partially inflatable commensurate with a single breath and/or rebreathing.

An atomizer, a liquid storage assembly thereof and an electron atomizing device are disclosed. The atomizer includes an atomizing core assembly having a liquid inlet. The liquid storage assembly includes a housing defining a liquid storage cavity and a first assembling hole, wherein the first assembling hole is configured to receive an end of an atomizing core assembly; an inner wall arranged in the liquid storage cavity, configured to sleeve around the atomizing core assembly, wherein a capillary gap is defined between the inner wall and an outer wall of the atomizing core assembly, and the capillary gap is configured to guide liquid in the liquid storage cavity to pass through the liquid inlet.

The present invention provides a dry powder inhaler comprising: a reservoir containing a dry powder formulation and an arrangement for delivering a metered dose of the medicament from the reservoir; a cyclone deagglomerator for breaking up agglomerates of the dry powder medicament; and a delivery passageway for directing an inhalation-induced air flow through a mouthpiece, the delivery passageway extending to the metered dose of medicament, wherein the formulation comprises an inhalable β.sub.2-agonist having a particle size distribution of d1O<1 μπ.Math.=1-3 μπ.Math., d90=3.5-6 μm and NLT 99% 10 μm and a lactose carrier.

A unit dose container for the containment of an intranasal formulation for use with the POD device.

The present invention relates to a feedback for inhalation. In order to further improve feedback and instructions to further support the correct use of an inhaler, a feedback apparatus (10) for inhalation is provided that comprises an inhaler interface (11), a processor (14), a feedback device (16), and a feature assigner (13). The inhaler interface is configured to temporarily attach the feedback apparatus to an inhalation apparatus. The feedback device is configured to provide a feedback to the user to aid in inhalation with the inhalation apparatus. The feature assigner is configured to identify a type of a predetermined feature of the attached inhalation apparatus, and the feedback device is configured to provide the feedback in dependency of the identified type of feature to instruct the user to adjust inhalation maneuver adapted to the attached inhalation apparatus. In an example, the predetermined feature is a device type of the inhalation apparatus, and the feature assigner is configured as an inhalation device type assigner (70) to identify the type of a currently used inhalation device. In another example, the predetermined feature is an accessory type of the inhalation apparatus, and the feature assigner is configured as an accessory type assigner (72) to identify the type of a currently used accessory.

Provided herein are systems for treating a subject with a pulmonary infection, for example, a nontuberculous mycobacterial pulmonary infection, a Burkholderia pulmonary infection, a pulmonary infection associated with bronchiectasis, or a Pseudomonas pulmonary infection. The system includes a pharmaceutical formulation comprising a liposomal aminoglycoside dispersion, and the lipid component of the liposomes consist essentially of electrically neutral lipids. The system also includes a nebulizer which generates an aerosol of the pharmaceutical formulation at a rate greater than about 0.53 gram per minute. The aerosol is delivered to the subject via inhalation for the treatment of the pulmonary infection.