Dispenser cap arrangements for enclosing a portion of a dispenser of a medicament are described herein.

Disclosed is a computer controlled dosage system, for dosage adjustment for a mobile, hand held, inhaler for delivering a dosage of a medicine, is provided. The system comprises at least one measuring device for measuring at least one parameter; and a handheld mobile computer separate from the inhaler, the computer being configured to communicate with the at least one measuring device and with a remote memory for sending and receiving information to and from patient medical records of the remote memory for storage in a memory of the computer, and the computer being configured to receive a manual input for storage in the memory of the computer. The computer is configured to create a data set for setting a plurality of levels of different dosages of medicine based on the medicine used by the inhaler, the information from the patient's medical records of the remote memory, and the manual input; and the computer is further configured to store the data set in the memory of the computer. The computer is further configured to generate an indication indicating a dosage adjustment for the inhaler, based on the at least one parameter and on one of the plurality of levels of dosage of the data set, the indication indicating one of the plurality of levels of dosage of the data set as the dosage adjustment for the inhaler. A dosage regime generated by the computer controlled dosage system is also disclosed.

A mobile inhaler is provided and a container for using therewith. The mobile inhaler comprises: a mouthpiece comprising at least one inhaling opening; a body element connected to the mouthpiece and comprising a housing for holding a DC power source; a power conversion unit comprising an inverter operative to convert a DC voltage provided by a DC power source, into a higher AC voltage; a nebulizer comprising an ultrasonic vibrator and a mesh, wherein the ultrasonic vibrator is activated by the AC voltage, and wherein the nebulizer is adapted to enable converting into aerosol droplets at least part of a liquid comprised in an enclosure, and the aerosol droplets to be directly inhaled from the mouthpiece; and an enclosure adapted to enable holding a liquid, and characterized in that it provides a connection to enable fluid transfer from the enclosure to the nebulizer.

A vibrating mesh nebuliser. The nebuliser (100, 400, 500) comprises a cartridge section (110, 420, 520) comprising a reservoir (180) containing a liquid to be nebulised (190), a mouthpiece comprising a conduit (160), wherein a flow path (210) is defined between the reservoir (180) and the conduit (160) and whereby a user may inhale nebulised liquid from the mouthpiece through the conduit (160). The nebuliser further comprises a body section (120, 410, 510), releasably connectable to the cartridge section (110, 420, 520) and a mesh section (530) comprising a vibratable mesh (250, 540), the vibratable mesh (250, 540) being disposable in the flow path (210), so as to nebulise liquid drawn from the reservoir to the conduit in the mouthpiece. Also provided are an apparatus and method for monitoring one or more physiological responses to material self-administered by a user.

Stable composition of anhydrous micronized ipratropium or a pharmaceutically acceptable anhydrous salt thereof and method of making.

A valve (1, 11, 19) for an inhalation device comprising an interior volume that is delimited at least partially by a valve wall (4, 17, 21), a permanent opening (29) as well as a valve functional area (6), whereby the valve functional area (6) is configured to be at least almost closed below an opening pressure difference and to be open above an opening pressure difference such that above the opening pressure difference, a fluid can flow through the permanent opening (29) into the interior volume and out of the valve functional area (6), the valve comprising an inversion protector that is configured to impede or prevent inversion of the valve wall (4, 17, 21).

A method of charging a container for use in a medication delivery apparatus wherein the propellant used comprises 1,1-difluoroethane (R-152a) is described.

A dry pharmaceutical composition is provided that is suitable for respiratory tract delivery of levodopa and DDI for treatment of Parkinson's disease or Parkinson syndrome. The dry pharmaceutical composition comprises levodopa, a dopa decarboxylase inhibitor (DDI) and at least one excipient. A unit dosage form of the dry pharmaceutical composition and a method of treating a patient with Parkinson's disease or Parkinson syndrome by administering the dry pharmaceutical composition are also provided.

A small form factor metered dose inhaler is disclosed. The inhaler includes a casing having a longitudinal axis and a transverse axis. The casing has a mouthpiece opening at one end along the longitudinal axis. The casing is configured to house a medicament canister along the longitudinal axis. The medicament canister contains a plurality of doses of a pulmonary medicament and a metered dose valve configured to release a metered dose of the pulmonary medicament through the mouthpiece opening along the longitudinal axis. A mechanical linkage translates an applied input force to the mechanical linkage into an output force along the longitudinal axis configured to actuate the metered dose valve and release the metered dose of the pulmonary medicament in a direction along the longitudinal axis. The aerosolized medicament exits the casing in a fluid flow which is symmetric in a vertical plane along the longitudinal axis.

An inhaler includes a main body having a canister housing, a medicament canister retained in a central outlet port of the canister housing, and a dose counter having an actuation member for operation by movement of the medicament canister. The canister housing has an inner wall, and a first inner wall canister support formation extending inwardly from a main surface of the inner wall. The canister housing has a longitudinal axis X which passes through the center of the central outlet port. The first inner wall canister support formation, the actuation member, and the central outlet port lie in a common plane coincident with the longitudinal axis X such that the first inner wall canister support formation protects against unwanted actuation of the dose counter by reducing rocking of the medicament canister relative to the main body of the inhaler.