A device including a body with a mouthpiece, a fluid reservoir mounted to slide relative to the body, a valve, a blocking element movable and/or deformable between a blocking position in which the metering valve cannot be actuated, and an actuation position in which the metering valve can be actuated; a trigger element movable and/or deformable between a locking position and a release position; and an inhalation-controlled trigger system. The blocking element including a projection that, in the locking position, co-operates with a shoulder of the trigger element to define a latch that prevents the blocking element from moving and/or deforming. The blocking element includes a lateral projection that, in the locking position of the trigger element, co-operates with a bearing surface of the trigger element to form, in the locking position of the trigger element, a second contact point between the blocking element and said trigger element.

A breath-powered, dry powder inhaler, a cartridge, and a pulmonary drug delivery system are provided.

There can be provided a device configured to impart flavouring to an airstream admitted the device prior to the airstream reaching an aerosol generator of the device, the device thereby operable to deliver a flavoured aerosol from an outlet.

A dry powder aerosol delivery device and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The dry powder aerosol delivery device includes a housing, a cartridge, and a dry powder dispersion mechanism, and at least one differential pressure sensor. The dry powder delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The dry powder aerosol delivery device is then actuated to generate a plume of particles having an average ejected particle diameter within the respirable size range, e.g., less than about 5-6 μm, so as to target the pulmonary system of the user.

The invention provides a method of testing an inhaler based on performing an optical analysis of a dry powder medicament plume discharged from the inhaler upon actuation. More particularly, embodiments of the invention comprise illuminating the dry powder plume with a source of electromagnetic radiation and capturing one or more images of a pattern of radiation reflected or diffracted by the illuminated plume. The images are subsequently processed to determine and/or analyse one or more geometric and/or dynamic characteristics of the plume.

Taught herein is a disposable breath actuated dry powder drug inhalation device having a powderized drug storage chamber with integral toroidal geometry and air flow pathways for entraining and breaking up powder aggregates prior to delivery to the patient. The toroidal chamber is fluidly connected by one or more air inlets directed in a non-tangent manner toward the powder to loft and set up an irregular-rotational flow pattern. Also, in fluid connection with the toroidal chamber is a centrally or near centrally located air and powder outlet consisting of one or more holes forming a grid in fluid connection with a channel providing a passageway for powder flow to the patient.

A device and method for delivering a fluid as an ejected stream of droplets during inhalation uses inertial filtering to cause a first plurality of droplet particles generated by an ejector mechanism to pass through an airflow exit while a second plurality of droplet particles having a greater mass mean aerodynamic diameter than the first plurality of droplet particles fails to pass through the airflow exit.

An inhaler device is operable to deliver a dose of an inhalable active ingredient. The inhaler device comprises a housing comprising a mouthpiece, a removable flow regulator at least partly received within the housing, the flow regulator defining a cavity operable to receive a vessel comprising the active ingredient, and an electronic component operable to monitor inhaler data and to transmit the inhaler data to a remote device. An inhaler system comprises, together with an inhaler or inhaler cap, a computer programme application operable, when run on a client device, to cause the client device to receive inhaler data from the electronic component.

To be accompanied, when published, by FIG. 1 of the drawings.

An inhaler (10) has a main body for accommodating a medicament reservoir (84), a canister fire system for moving a canister (50) to release a dose in response to air flow, a cap housing (12) for enclosing the canister fire system and canister within an interior chamber defined by the main body (14) and a cap housing, wherein a lock system (250) is provided for locking the cap housing on the main body.

A nasal inhaler for the inhalation of inhalable substances comprise: a canister having an interior reservoir containing pressurised inhalable substances including fluid; a metering valve including a metering chamber and a valve stem defining a communication path between the metering chamber and the interior reservoir, the communication path including an opening configured to permit flow between a transfer space inside the valve stem and the interior reservoir, the interior reservoir being arranged for orientation above the metering chamber whereby gas located within the metering chamber is replaced with liquid from the interior reservoir.