An apparatus for controlling positioning of a subject's jawbone including an expandable device expandable to apply a force on the subject's jawbone in a direction of an anterior position with respect to a subject's skull; a mounting device holding the expandable device in proximity to the subject's jawbone to facilitate application of the force on the subject's jawbone and configured to position the expandable device behind the subject's jawbone such that application of the force on the subject's jawbone rotates the subject's jawbone relative to the subject's skull towards the anterior position; and a control system configured to control the force in response to the control system receiving an indication of a change in at least one of: an oxygen level of the subject; a gas flow rate of therapy gas supplied to the subject; a position and/or orientation of the subject; and/or a sleep state of the subject.

Provided are a mask, a sample collecting tube, and a pathogen collecting apparatus. The mask includes a mask body, a breather valve fixed on the mask body, and a sampling structure including a pathogen adsorption portion. The pathogen adsorption portion is disposed on an inner side of the breather valve and is adapted to adsorb pathogens in exhaled gas. The pathogen adsorption portion is adapted to enter the sample collecting tube to be in contact with a sample preservation solution in the sample collecting tube.

A catheter body (210) defines a distal-most suction orifice (444) and an outer lateral wall (592), which defines a lateral opening (448) therethrough into a suction lumen (530). An inflatable-element outer wall (590) of an inflatable element (588) is mounted to the catheter body (210). An inner membrane (589) is positioned within the inflatable element (588) and is mounted to the catheter body (210) around the lateral opening (448) along a seal perimeter (583) around the lateral opening (448), so as to define a collapsible membrane portion (596) that (a) covers the lateral opening (448), and (b) together with the inflatable-element outer wall (590), defines an inflatable chamber (587) between the inflatable-element outer wall (590) and the collapsible membrane portion (596). The inner membrane (589) entirely surrounds the catheter body (210).

A catheter body (210) defines a distal-most suction orifice (444) and an outer lateral wall (592), which defines a lateral opening (448) therethrough into a suction lumen (530). An inflatable-element outer wall (590) of an inflatable element (588) is mounted to the catheter body (210). An inner membrane (589) is positioned within the inflatable element (588) and is mounted to the catheter body (210) around the lateral opening (448) along a seal perimeter (583) around the lateral opening (448), so as to define a collapsible membrane portion (596) that (a) covers the lateral opening (448), and (b) together with the inflatable-element outer wall (590), defines an inflatable chamber (587) between the inflatable-element outer wall (590) and the collapsible membrane portion (596). The inner membrane (589) entirely surrounds the catheter body (210).

A mask system for delivery of respiratory therapy to a patient includes a nares portion and a mouth portion and an inlet conduit connected to at least one of the nares portion and the mouth portion to deliver the pressurized, breathable gas. The mask system is adapted to selectively utilize the nares portion and/or the mouth portion in a first mode utilizing both the nares portion and the mouth portion, and in a second mode utilizing the nares portion and not utilizing the mouth portion.

A mask system for delivery of respiratory therapy to a patient includes a nares portion and a mouth portion and an inlet conduit connected to at least one of the nares portion and the mouth portion to deliver the pressurized, breathable gas. The mask system is adapted to selectively utilize the nares portion and/or the mouth portion in a first mode utilizing both the nares portion and the mouth portion, and in a second mode utilizing the nares portion and not utilizing the mouth portion.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient includes a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the respiratory gas is controlled by a microprocessor, a mixing area for mixing a first gas and a second gas in the respiratory gas flow pathway, a humidification area downstream of the mixing area and configured for humidifying respiratory gas in the respiratory gas flow pathway, and a heated delivery conduit for minimizing condensation of humidified respiratory gas.

A ventilator includes electronic control circuitry configured to control a supply of breathing gas for a plurality of respiratory cycles, measure a volume received by the patient in each of the plurality of respiratory cycles, and determine, for each cycle of the plurality of respiratory cycles, a cycle score corresponding to a deviation between the volume of the cycle and a predetermined target volume. The determined cycle score can be selected from a predetermined number of cycle scores that span positive and negative numbers based on the deviation. A pressure step value can be determined based on a plurality of cycle scores corresponding to the plurality of respiratory cycles, and a current pressure of the breathing gas is adjusted by an amount corresponding to the determined pressure step value. The pressure step value may be generated by dividing a sum of the plurality of cycle scores by a sample size.

A respiratory device comprising a housing enclosing a chamber and an orientation indicator moveable with respect to the housing between a first position indicative of an orientation of the housing predetermined to be suitable for operation of the respiratory device, and a second position indicative of an orientation of the respiratory device predetermined to be less suitable for operation of the respiratory device. The orientation indicator is positioned in a location on the respiratory device visible to a user during the operation of the respiratory device.