The methods, systems, and devices disclosed herein generally involve a venous-to-venous delivery of drugs to a targeted region within a patient. A triple lumen catheter device is disclosed that is particularly suitable for delivery of therapeutic drugs via a closed loop, preventing the circulation of toxic agents throughout the body, thereby creating an isolated treatment zone that maximizes local therapeutic concentrations while preventing agents from escaping to the rest of the body.

A urodynamic investigation apparatus for receipt of urine from a bladder is provided. The apparatus is characterized by a tubular element, first and second fittings, and a sleeve element, for select passage of urine there through, within the tubular element. The tubular element is characterized by opposing first and second end portions, and a port. The fittings are adapted to be received by the opposing end portions of the tubular element so as to delimit an apparatus chamber. The sleeve element, suspended between the fittings within the chamber, has collapsed and open configurations. The collapsed configuration is indicative of a no urine flow condition, and the open configuration indicative of a urine flow condition, with the sleeve element urine flow condition being a function of pressure applied to the chamber via the port of the tubular element.

Devices, methods, and systems are provided for occluding a collateral flow channel between a target lung compartment and an adjacent lung compartment. A video-assisted thoracoscopic device is inserted into a thoracic cavity of a patient and positioned at a fissure between a target lung compartment and an adjacent lung compartment. A collateral flow channel between the target lung compartment and the adjacent lung compartment is then identified using the video-assisted thoracoscopic device and an agent is injected into the collateral flow channel, thereby reducing the collateral flow channel.

Novel catheter with longitudinal expandable arid contractile elements which promote wave propagation. The tension-band characteristics of these elements enhance the crawling dynamics of the catheter. Tauglit is an aspiration catheter with three key components: an inner spring coil system, a soft pleated jacket with annuli that buckles under load and an outer proleg or leaf-spring that fattens the. diameter of the catheter. Smart features, robotics and AI may be on-boarded. As shown, subject catheters shall piston in a fixed environment (muscular structure such as an artery) and propagate forward akin to earthworm locomotion (Lumbricm terrestris).

A gastrostomy device (100) comprises a gastrostomy tube (200) having a retainer lumen (235) extending between a proximal part and a distal part of the tube (200); and an inflatable retaining element (300) coupled to the tube (200) at the distal part. An interior space of the retaining element (300) is in fluid communication with the retainer lumen (300). The gastrostomy device (100) also comprises an indicator (410) being in fluid communication with the retainer lumen (235) at the proximal part of the tube (200). The indicator (410) is configured for indicating a pressure in the retaining element (300) continuously within a range from a pressure corresponding to an empty retaining element (300) to an optimal pressure for the inflated retaining element (300).

Systems, devices and methods for draining and analyzing bodily fluids, pressures and assessing health are described where a drainage system generally comprises an elongate catheter having a first end and at least one opening in fluid communication with a catheter lumen, a drainage tube having a drainage lumen in fluid communication with a second end of the catheter, a fluid reservoir in fluid communication with the drainage lumen, and a pressure sensing membrane in communication with a pressure lumen defined through the catheter. The system also includes a pressure sensor coupled to the pressure lumen and configured to receive an intra-abdominal pressure signal from the pressure sensing membrane via the pressure lumen, and a controller in communication with the fluid reservoir and the pressure sensor. The controller is configured to determine an abdominal perfusion pressure based on the intra-abdominal pressure and a mean arterial pressure received by the controller.

A catheter system may include a catheter adapter, which may include a side port. The catheter system may include a catheter, and an extension tube having a distal end and a proximal end. The catheter system may include a three-port connector, which may include a distal port, a proximal port, and a side port. The proximal end of the catheter adapter may be coupled to the distal port of the three-port connector. The distal end of the extension tube may be integrated with the side port of the three-port connector.

A urodynamic investigation apparatus for receipt of urine from a bladder is provided. The apparatus is characterized by a tubular element, first and second fittings, and a sleeve element, for select passage of urine there through, within the tubular element. The tubular element is characterized by opposing first and second end portions, and a port. The fittings are adapted to be received by the opposing end portions of the tubular element so as to delimit an apparatus chamber. The sleeve element, suspended between the fittings within the chamber, has collapsed and open configurations. The collapsed configuration is indicative of a no urine flow condition, and the open configuration indicative of a urine flow condition, with the sleeve element urine flow condition being a function of pressure applied to the chamber via the port of the tubular element.

The present disclosure relates to a multifunctional epidural catheter being equipped with a sensor for detecting a pressure applied to a combined balloon. And, most particularly, provided herein is a multifunctional epidural catheter being equipped with a sensor for detecting a pressure applied to a combined balloon, wherein the catheter comprises a main body, and a catheter insertion part being connected to the main body and inserted in a patient's body, wherein the catheter has a combined balloon attached to one side of the catheter insertion part that is inflated when the catheter is inserted in the patient's body so as to expand an empty space within the patient's body, the multifunctional epidural catheter comprising a syringe connection part for a balloon formed on one side of the main body to protrude outside and having a syringe for the balloon connected thereto so as to supply fluid into the balloon, a fluid transfer part being formed inside the main body, having one end connected to the syringe connection part for a balloon, and transferring the fluid supplied from the syringe to be supplied to the balloon, a pressure sensor being formed inside the main body, contacting the fluid transfer part, and measuring a pressure of the fluid according to an expansion or contraction of the balloon, a display unit being formed on an external side of the main body, receiving a measurement value detected by the pressure sensor, and numerically displaying the received value, and an alarm unit generating a visual or auditory alarm when the pressure measured by the pressure sensor reaches a threshold value.

A catheter-based baro-hydrometer device measures or otherwise monitors esophageal function. The device includes a segmented balloon design, including a first and second balloon whose fill volumes can be independently controlled. In general, the device leverages secondary peristalsis related to balloon distention in order to study esophageal function. Pressure sensors coupled to the balloons record pressure data, which can be classified and processed to measure or otherwise monitor esophageal function.