A catheter (100) for treating hypervolemia in a patient includes a luminal ingress (112) joined to a luminal egress (114) at a distal end portion (116) of the catheter having a closed distal end (102). The distal end portion is configured to at least temporarily reside within a vessel of the patient, the distal end portion including a semipermeable membrane. The luminal ingress is designed to convey an influent having a first osmotic concentration to the distal end portion. The semipermeable membrane is configured to pass blood-borne water from the vessel into the distal portion. The blood-borne water is absorbed by the influent to produce an effluent having a second osmotic concentration lower than the first osmotic concentration. Systems (200) with the catheter and methods for treating hypervolemia are also disclosed.

A device for intravascular intervention can comprise an interventional element, an elongate manipulation member having a retention portion, and a joining element. The elongate element can comprise a distally located attachment portion. The interventional element includes a proximal end portion with a hole therethrough, the attachment portion of the elongate member extending through the hole at the bend such that first and second segments of the elongate member each extend proximally from the hole. A retention portion includes an arm extends proximally of the hole and a shoulder protruding radially outwardly from a proximal portion of the arm. A joining element circumferentially surrounds at least a portion of the retention portion and at least a portion of the first and second segments of the elongate member such that a proximal end of the joining element is positioned distal to the shoulder of the retention portion.

A delivery system for an implantable medical device includes an outer shaft defining an outer shaft lumen and an inner shaft translatable within the outer shaft lumen, the inner shaft defining a lumen extending through the inner shaft. An actuation mechanism extends through the lumen and includes a coupler, a force translation rod that extends proximally from the coupler and a plurality of push pull rods that extend distally from the coupler and that releasably couple to the implantable medical device. The force translation rod includes a transition in electromagnetic permeability. The delivery system includes an inductive coil disposed relative to the force translation rod and positioned to detect a change in inductance resulting from the transition in electromagnetic permeability passing through the inductive coil.

A flexible elongated tube for a catheter system includes a tubing wall. The wall has a plurality of first indentations spaced apart from each other along a longitudinal axis (L) of the tube and a plurality of second indentations spaced apart from each other along the longitudinal axis (L). An axially aligned pair of indentations has a non-impressed section between the axially aligned pair of indentations. The axially aligned pair of indentations and the non-impressed section form a pull wire space.

A detachable tip sheathed balloon microcatheter is provided for delivering an embolic agent to a target location for the embolization of an arteriovenous malformation (AVM). The detachable tip sheathed balloon microcatheter including a balloon microcatheter including a first shaft and an inflatable balloon that is coupled to a distal end portion of the first shaft; and a detachable tip assembly that is configured to be detachably coupled to the first shaft of the balloon microcatheter. The detachable tip assembly includes a protective balloon sheath that is coupled to a proximal end portion of the second shaft, wherein when the detachable tip assembly is coupled to the balloon microcatheter, the protective balloon sheath surrounds at least a portion of the inflatable balloon.

A system for delivering an implant within a patient is disclosed. The activation of the heater coil causes the degradation, melting or reduction of a component that brings the heater coil into or out of electrical contact with another component, or causes the individual loops of the coil to contact each other, thereby resulting a notable change in resistance in the circuit supplying the heater coil with electricity. A core wire terminates prior to the distal end of the device, allowing for greater flexibility.

A medical device and methods of use are disclosed herein. The medical device includes a base microcatheter and a microcatheter tip assembly detachably coupled to a first end of the base microcatheter. The microcatheter tip assembly includes a body defining at least one lateral hole and a loading region, and an opening in a first end of the microcatheter tip assembly. The medical device includes a membrane carrier disposed within the loading region of the microcatheter tip assembly. The membrane carrier includes a body defining an opening, and a membrane covering the opening in the membrane carrier. The membrane is configured to rupture in response to a force applied to the membrane. When the membrane is disposed within the loading region of the microcatheter tip assembly and the membrane is not ruptured, the membrane is configured to prevent the flow of material through the opening in the first end of the microcatheter tip assembly.

An apparatus is provided for connecting and disconnecting a tubular fitting connector to a fluid conduit. A cradle assembly accommodates the fluid conduit, and includes a body having a first port and a second port. The first and second ports are disposed at opposite ends of the body, and each port is configured for receiving an end cap of the tubular fitting to fasten or unfasten the end cap for replacement. A connector holder is disposed between the first and second ports, and is configured for accommodating insertion of the connector. A holder assembly is provided for accommodating insertion of the tubular fitting. The cradle assembly is reciprocable relative to the holder assembly for transitioning the cradle assembly between a first position, a second position, and a third position.

A control handle for a steerable catheter allows for precise manipulation of the distal catheter tip in a target organ or vessel using only one hand. The control handle can have a single articulating knob capable of both linear translation along and rotation about the axis of the handle. These functions of the articulating knob actuate both the expansion and retraction of an expandable member, as well as bi-directional deflection of the distal catheter tip. The articulating knob functions with consistency regardless of the orientation of the handle, with ergonomic movements allowing the user to comfortably keep their attention on the procedure's monitoring equipment. These improvements can lead to safe and more rapid procedure times for procedures such as diagnostics and cardiac ablation.

Microcatheters and methods for modifying and delivering suspended particles to target bodily parts (e.g., of a cardiovascular system). Embolization microcatheters and uses thereof in performing local embolization procedures, involving modifying flow characteristics (momentum) of suspensions during delivery. Applicable for delivering embolization material in a small blood vessel towards a target bodily part, and for performing local embolizations in small blood vessels feeding (possibly, cancerous) target bodily parts, thereby forming emboli therein, while preventing or minimizing non-target embolization. An exemplary catheter includes: a tubular wall with proximal and distal wall ends, and a lumen extending therebetween, opened and configured to allow passage of a suspension to a distal outlet; the distal outlet shaped or/and sized to allow passage of both a suspension fluid and particles; a proximal outlet configured to allow passage of the suspension fluid without particles and to block passage of the particles, during delivery of the suspension.