The present invention relates to a catheter and method for detecting electrical activity in an organ. The catheter comprises: a proximal end with connection means for connecting to a signal processing system and a distal end for being inserted into a patient's organ, at least 3 arms extending from the distal end, each arm comprising at least one electrode. The catheter further comprises a central electrode at the distal end of the catheter. The method comprises: inserting a multi-electrode catheter into a patient's organ; obtaining and conditioning a positioning signal for positioning the electrodes; obtaining causal information about the current location; processing and summarizing the causal information obtained together with causal information about previous locations; visually presenting a recurrence plot of all the causal information obtained; and then moving the catheter to a new location and repeating the method until obtaining a complete recurrence plot.

Provided is an endoscope sheath including: a sheath body having an elongated rotating section and a stationary section, which are coupled to each other in a relatively rotatable manner about a longitudinal axis; a first passage along the axis; a second passage parallel to the first passage; an outlet through which a proximal end of an injection needle inserted in the second passage is pulled outside, the outlet being capable of changing a pullout position of the proximal end of the needle relative to the stationary section in the circumferential direction; and holders provided in the stationary section and separated by intervals in the circumferential direction, each holder securing an injector having the needle to the stationary section at a position where the needle protrudes from the distal end of the body and releasing the injector at a position where the needle is accommodated inside the body.

A method of monitoring a fluid injection procedure is provided. The method includes: disposing a sensor on a catheter, where the sensor is in proximity to a tip of the catheter; inserting at least the tip of the catheter into a patient; delivering a fluid to a location within the patient via the tip of the catheter; and automatically monitoring a sensor signal from the sensor while the fluid is being delivered. Reflux end-point detection using an electrical impedance sensor has been demonstrated in a phantom. Applications include embolotherapy and angiography.

A catheter system may include an outer catheter adapter, an outer catheter having an outer catheter lumen extending through the outer catheter, and an inner surface forming the outer catheter lumen. The catheter system may further include an inner catheter adapter, an inner catheter lumen extending through the inner catheter adapter and an inner catheter extending distally from the inner catheter adapter such that the inner catheter is disposed within the outer catheter lumen and the inner catheter and the inner catheter adapter are configured to move with respect to the outer catheter and the outer catheter adapter between a proximal position and a distal position.

A catheter (100) for treating hypervolemia in a patient includes a luminal ingress (112) joined to a luminal egress (114) at a distal end portion (116) of the catheter having a closed distal end (102). The distal end portion is configured to at least temporarily reside within a vessel of the patient, the distal end portion including a semipermeable membrane. The luminal ingress is designed to convey an influent having a first osmotic concentration to the distal end portion. The semipermeable membrane is configured to pass blood-borne water from the vessel into the distal portion. The blood-borne water is absorbed by the influent to produce an effluent having a second osmotic concentration lower than the first osmotic concentration. Systems (200) with the catheter and methods for treating hypervolemia are also disclosed.

The present embodiments provide systems and methods suitable for delivering a therapeutic agent to a target site. In one example, the system comprises a container for holding the therapeutic agent, and a pressure source having pressurized fluid, wherein the pressure source is in selective fluid communication with at least a portion of the container. A catheter is placed in fluid communication with the container, and has a lumen sized for delivery of the therapeutic agent to a target site. A housing is configured to securely retain the container. The system further comprises a camera having a camera head coupled to the catheter, wherein the camera provides a visual image of the target site during delivery of the therapeutic agent.

Embodiments herein include gas sampling catheters, systems and related methods. In an embodiment, a gas sampling catheter is included. The catheter can include a catheter shaft having a proximal end and a distal end, the catheter shaft defining a lumen therein. The catheter can include a gas sampling port providing fluid communication between the exterior of the catheter shaft adjacent the distal end of the lumen of the catheter shaft. The catheter can further include a sensor element disposed in fluid communication with the lumen, the sensor element configured to detect a component of a gaseous sample. The sensor element can include a first measurement zone comprising a plurality of discrete binding detectors. Other embodiments are also included herein.

In some examples, a catheter includes an elongated body including a proximal portion and a distal portion. The elongated body includes an inner liner, an outer jacket, a structural support member positioned between at least a portion of the inner liner and at least a portion of the outer jacket, and an expandable member coupled to the structural support member at the distal portion of the elongated body. The expandable member may be configured to expand radially outward, e.g., to engage a clot within vasculature of a patient.

Methods of treatment, pharmaceutically acceptable solutions, and implantable devices are provided for the intrathecal treatment of AED-resistant seizures using levetiracetam.

This disclosure relates to procedures for administering a blockade of the sphenopalatine ganglion (“SPG”). Methods may include advancing a catheter through nostril at least 8 cm. Methods may include advancing the catheter through an inferior meatus. Methods may include causing the catheter to bend after contacting posterior wall of the nasal cavity. Methods may include advancing the catheter superiorly to a position posterior to the middle turbinate. Methods may include advancing the catheter superiorly to a position posterior to the superior turbinate. Methods may include advancing the catheter superiorly into a sphenoethmoid recess. Methods may include bringing a distal tip of the catheter in contact with the SPG. Methods may include ejecting an anesthetic from a distal tip of the catheter and bathing the SPG to administer a blockade of the SPG.