Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt an pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.

Provided herein are devices and systems for depositing a material or manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. Further provided are methods of using the devices and systems, as well as methods of manufacturing a product, such as a pharmaceutical dosage form, by additive manufacturing. In certain embodiments, the device includes a material supply system configured to melt an pressurized a material, a pressure sensor configured to detect a pressure of the material within the device, and a control switch comprising a sealing needle operable in an open position and closed position. The sealing needle extends through a feed channel containing the material and includes a taper end, wherein the tapered end of the sealing needle engages a tapered inner surface of a nozzle to inhibit flow of the material through the nozzle when the sealing needle is in the closed position.

A system is disclosed for additively manufacturing a composite structure. The system may include a support, and a print head operatively connected to and moveable by the support. The print head may include an outlet configured to discharge a material in a trajectory along a central axis of the outlet, and a compactor disposed downstream of the outlet relative to the trajectory and configured to press the material transversely against an adjacent surface. The outlet may be configured to translate relative to the compacting module.

A system is disclosed for additively manufacturing a composite structure. The system may include a support, and a print head operatively connected to and moveable by the support. The print head may include an outlet configured to discharge a material in a trajectory along a central axis of the outlet, and a compactor disposed downstream of the outlet relative to the trajectory and configured to press the material transversely against an adjacent surface. The outlet may be configured to translate relative to the compacting module.

A three-dimensional printing system includes a print engine and a controller. The controller in turn includes a processor coupled to a non-transient memory. The non-transient memory stores software instructions that when executed by the processor cause the controller to operate the print engine to fabricate a body. The body includes a three-dimensional arrangement of 3D articles that are pairwise coupled together. An individual pair of the arrangement of 3D articles includes a first article and a second article. A curved body couples a first surface of the first article to the second article. The curved body intersects the first surface to define a closed intersection curve that bounds a break surface. Along the closed intersection curve a surface of the curved body subtends an acute angle with the first surface.

A three-dimensional printing system includes a print engine and a controller. The controller in turn includes a processor coupled to a non-transient memory. The non-transient memory stores software instructions that when executed by the processor cause the controller to operate the print engine to fabricate a body. The body includes a three-dimensional arrangement of 3D articles that are pairwise coupled together. An individual pair of the arrangement of 3D articles includes a first article and a second article. A curved body couples a first surface of the first article to the second article. The curved body intersects the first surface to define a closed intersection curve that bounds a break surface. Along the closed intersection curve a surface of the curved body subtends an acute angle with the first surface.

A 3D printing apparatus of the bottom-up photo-curing type, including a tank containing a liquid photo-curing material and at least one source of a radiation designed to obtain the photo-curing of the liquid photo-curing material, the bottom of the tank including an elastic membrane of non-stick material and transparent to the radiation of the light source, the tank supported on a support plate, the support plate includes, in the portion below the bottom of the tank, a mobile support element, which is able to move by translating and/or rotating in the plane where it is positioned with one or more perforated or lowered portions. The embodiments also relate to a method of using the apparatus for 3D printing.

A 3D printing apparatus of the bottom-up photo-curing type, including a tank containing a liquid photo-curing material and at least one source of a radiation designed to obtain the photo-curing of the liquid photo-curing material, the bottom of the tank including an elastic membrane of non-stick material and transparent to the radiation of the light source, the tank supported on a support plate, the support plate includes, in the portion below the bottom of the tank, a mobile support element, which is able to move by translating and/or rotating in the plane where it is positioned with one or more perforated or lowered portions. The embodiments also relate to a method of using the apparatus for 3D printing.

The present disclosure various apparatuses, and systems for 3D printing. The present disclosure provides three-dimensional (3D) printing methods, apparatuses, software and systems for a step and repeat energy irradiation process; controlling material characteristics and/or deformation of the 3D object; reducing deformation in a printed 3D object; and planarizing a material bed.

The present invention provides a swarm manufacturing platform, based on a swarm 3D printing and assembly (SPA) platform as a model for future smart factories, consisting of thousands of IoT-based mobile robots performing different manufacturing operations with different end effectors (e.g., material deposition, energy deposition, pick and place, removal of materials, screw driving, etc.) and real-time monitoring. The swarm manufacturing platform transforms a 1-D factory into a 2-D factory with manufacturing robots that can move across the 2-D factory floor, work cooperatively with each other on the same production jobs, and re-configure in real-time (i.e., the manufacturing robots can be digitally controlled to move, re-group, calibrate, and work on a new job in real-time).