Systems and methods for locally engaging tissue using suction. In at least one catheter device embodiment, the catheter device comprises an engagement catheter having a proximal end, a distal end, and a vacuum lumen therethrough operably coupling the proximal and distal ends; an elongated tube of a shape memory material having a plurality of elongated strips removed from a length of the elongated tube to form elongated shape memory tines at a distal end of the tube, wherein the shape memory tines flare outward away from a central axis to form a fluted distal end; and an elastomeric coating disposed over the elongated shape memory material tines to form a suction cup shape.

Devices used to provide access the vasculature are disclosed. The devices may be configured to provide access to a blood vessel, such as an artery. The devices may include a catheter assembly disposed over a needle assembly. The devices may also include a barrel assembly coupled to the needle assembly. A guidewire may be displaceable by barrel assembly within a needle. The needle may include a proximal and distal port.

A steerable medical instrument, such as a catheter or endoscope, comprises a tubular body having non-steerable section and steerable sections arranged from a proximal end to a distal end thereof. The tubular body defines a tool channel and a plurality of wire conduits formed along the wall of the tubular body. The steerable section includes wire-guiding members arranged in lengthwise direction alternated with void regions. A control wire arranged in a first conduit within the wall of the tubular body is connected to an actuator and transfers an actuating force to bend the steerable section. An electrical cable arranged along the wall of the tubular body has strain relief elements. The strain relief elements are portions of the cable arranged in at least one void region and configured to freely move within the void regions to provide strain relief to the electrical cable when the tubular body bends.

Aspects of the present disclosure include catheter devices in which a bushing is disposed in an interior cavity of a catheter hub. The bushing has a flexible portion extending out a distal end of the catheter hub. A catheter tube is sleeved over the flexible portion. A needle hub with a needle projects through the flexible portion of the bushing and the catheter tube. The flexible portion is bendable to form at least one curve along the flexible portion. The at least one curve has a minimum bend radius when a first surface of the flexible portion is extended and a second surface opposite the first surface of the flexible portion is shortened.

Disclosed embodiments relate to devices and related methods for delivering a composition to a subject. In some embodiments, a device may include a catheter coupled to a handle. The handle may include proximal and distal handle portions that are moveable relative to one another to selectively expose a needle at a distal end of the catheter. The proximal handle portion may include a container coupling and a grip extending proximally from the container coupling.

A splittable sheath includes a splittable sheath body, a splittable sheath hub, and a valve element. The sheath body comprises a generally flexible tubular structure, a proximal end, and a distal end. The sheath body defines a longitudinal axis and is splittable into two halves along a pre-determined line generally parallel to the longitudinal axis. The sheath hub extends from the proximal end of the sheath body and defines a longitudinal axis generally aligned with the longitudinal axis of the sheath body. The sheath body and sheath hub form an inner cavity along their respective longitudinal axes. The valve element includes a resilient plate and a sealing element. The resilient plate includes a distal portion extending radially inwardly from a side of the inner cavity. The sealing element includes a sealing surface and is supported by the resilient plate such that the sealing element is biased toward a position against a second sealing surface on at least one of the splittable sheath body and hub to substantially seal the inner cavity.

A hub assembly for connection to a medical device. The hub assembly may comprises an outer component having a proximal end, a distal end, and a cavity extending from the proximal end to the distal end. The hub assembly may further include an insert having a proximal end, a distal end, and a lumen extending from the proximal end to the distal end positioned at least in part within the cavity of the outer component. The insert may have a lumen extending from the proximal end to the distal end thereof. The outer component may be formed from a first material and the insert may be formed from a second material different from the first material.

A hub defines a lumen with a longitudinal axis along the length of the hub. An outer surface of a distal portion of the hub tapers inwardly toward the longitudinal axis as the distal portion extends distally. A strain relief includes a proximal portion configured to receive the distal portion of the hub. The strain relief defines a lumen that substantially aligns with the hub lumen when the proximal portion receives the hub. The hub and/or strain relief are configured to be fixedly attached to a catheter body such that a catheter body lumen substantially aligns with the hub lumen and the strain relief lumen when the strain relief receives the distal portion of the hub. Outer surfaces of the strain relief and hub define substantially similar distances to the longitudinal axis along an interface between the two outer surfaces when the strain relief receives the hub.

A system and method for delivering a medicament including a catheter configured for implantation in different target tissue sites, extending from a proximal end to a distal end, and having a sidewall which defines an internal lumen. The distal end has one or more apertures in the sidewall for the release of the medicament into the target tissue site; the system also comprises a medicament reservoir fluidly communicable with the internal lumen of each catheter, an adhesive member configured to adhere to the skin of the patient around the exit wound and having an opening therein to allow the catheters to pass through the adhesive member and a retaining member configured to be overlaid on the adhesive member and comprising a guide surface configured to receive a length of the two or more catheters and a plurality of retaining portions to retain the catheters against the guide surface.

The present embodiments provide strain relief members for a medical device delivery system, methods of use, and methods of manufacturing. In one embodiment, a medical device delivery system may include a body member with a first end having a first outer diameter, a second end having a second outer diameter, an inner surface facing a lumen that extends axially through the body member along a longitudinal axis, and an outer surface opposite to the inner surface. The embodiment also includes a threaded first connector at the first end of the body member. The outer surface of the body member may include a plurality of depressions. The body member may include a first material. The first connector may include a second material. The first material is more flexible than the second material. A portion of the outer surface of the body member may cover a portion of the first connector.