A fluid mechanics-based analysis tool is implemented to compute pressure field data, fluid velocity data, and/or muscular work data in a lumen or other tubular organ or structure from planimetry and pressure data (e.g., measured using a balloon dilation or other planimetry catheter). In this way, flow data can be estimated, which are otherwise insensible from current planimetry catheter technologies due to economic and/or manufacturing limitations.

A fluid mechanics-based analysis tool is implemented to compute pressure field data, fluid velocity data, and/or muscular work data in a lumen or other tubular organ or structure from planimetry and pressure data (e.g., measured using a balloon dilation or other planimetry catheter). In this way, flow data can be estimated, which are otherwise insensible from current planimetry catheter technologies due to economic and/or manufacturing limitations.

A fluid pressure gun device for a balloon catheter includes a tubular cavity, a fluid tube, a pressure monitoring device, a plunger, a screw structure, a cover and a detent structure, wherein inside the body of the cavity forms a chamber. The plunger is disposed in the chamber, and the inside of the casing forms a chamber. The screwing structure includes two screwing blocks, and each screwing block is oppositely arranged in the chamber according to the plunger as the center. Each of the screw blocks is screwed with the plunger, and a plurality of springs respectively lean against the screw block and the cover. The detent structure is used to depart the screw blocks from the plunger. The plunger is supported by each screw block at least on two opposite sides, and making it a highly reliable combination of the plunger and each screw block.

A fluid pressure gun device for a balloon catheter includes a tubular cavity, a fluid tube, a pressure monitoring device, a plunger, a screw structure, a cover and a detent structure, wherein inside the body of the cavity forms a chamber. The plunger is disposed in the chamber, and the inside of the casing forms a chamber. The screwing structure includes two screwing blocks, and each screwing block is oppositely arranged in the chamber according to the plunger as the center. Each of the screw blocks is screwed with the plunger, and a plurality of springs respectively lean against the screw block and the cover. The detent structure is used to depart the screw blocks from the plunger. The plunger is supported by each screw block at least on two opposite sides, and making it a highly reliable combination of the plunger and each screw block.

Apparatus, systems, and methods provide access to the renal pelvis of a kidney to treat renal nerves embedded in tissue surrounding the renal pelvis. Access to the renal pelvis may be via the urinary tract or via minimally invasive incisions through the abdomen and kidney tissue. Treatment is effected by exchanging energy, typically delivering heat or extracting heat through a wall of the renal pelvis, or by delivering active substances.

A catheter having a shaft including a first lumen that communicates from the proximal end to the distal end of the shaft, and a second lumen that is positioned on the outer periphery side of the first lumen, communicates from the proximal end side to the distal end side of the shaft, and has a smaller opening area than the opening area of the first lumen in a transverse section of the shaft. The dimension in the first direction in the distal end portion of the shaft where the first lumen and the second lumen are aligned is less than or equal to the dimension in the first direction in the proximal end portion that is closer to the proximal end side than the distal end portion of the shaft.

A catheter having a shaft including a first lumen that communicates from the proximal end to the distal end of the shaft, and a second lumen that is positioned on the outer periphery side of the first lumen, communicates from the proximal end side to the distal end side of the shaft, and has a smaller opening area than the opening area of the first lumen in a transverse section of the shaft. The dimension in the first direction in the distal end portion of the shaft where the first lumen and the second lumen are aligned is less than or equal to the dimension in the first direction in the proximal end portion that is closer to the proximal end side than the distal end portion of the shaft.

An apparatus, assembly and method for controlling release of a drug from a drug-eluting balloon during delivery of a drug-eluting balloon to a situs within a body. More particularly, the present invention relates to a diametrically expandable sleeve having a first non-diametrically unexpanded state in which drug retained on or in a drug-eluting balloon is protected from release by a sleeve and a second diametrically expanded state in which drug retained on or in the drug-eluting balloon is exposed for focal release in the body by diametric expansion of the sleeve, exposing openings in the sleeve during diametric expansion and closing the openings in the sleeve when the sleeve is in its diametrically unexpanded state.

An apparatus, assembly and method for controlling release of a drug from a drug-eluting balloon during delivery of a drug-eluting balloon to a situs within a body. More particularly, the present invention relates to a diametrically expandable sleeve having a first non-diametrically unexpanded state in which drug retained on or in a drug-eluting balloon is protected from release by a sleeve and a second diametrically expanded state in which drug retained on or in the drug-eluting balloon is exposed for focal release in the body by diametric expansion of the sleeve, exposing openings in the sleeve during diametric expansion and closing the openings in the sleeve when the sleeve is in its diametrically unexpanded state.

Embodiments of the present invention provide a method of treating a stricture in a nonvascular body lumen such as urethral strictures, benign prostatic hyperplasia (BPH) strictures, ureteral strictures, esophageal strictures, sinus strictures, and biliary tract strictures. Embodiments of the present invention provide a method for treating at least one of benign prostatic hyperplasia (BPH), prostate cancer, asthma, and chronic obstructive pulmonary disease (COPD). The method can include delivering, for example, via drug coated balloon catheters, anti-inflammatory and anti-proliferative drugs (e.g., rapamycin, paclitaxel, and their analogues) and one or more additives.