A method and an annular integral gasket are provided for forming a sealing connection between a first tubular member and a second tubular member. The integral gasket comprises at least one flexible sealing portion adapted to form a sealing connection between a first tubular member and a second tubular member. The integral gasket further comprises a bonding layer adapted to be fixedly attached to a tubular member by a joining process. The integral gasket also comprises a body region adapted for supporting the flexible sealing portion and the bonding layer.

The invention describes a device and method for making corrugated products. The device can be used with any substrate and includes, at least, first and second drive rollers for driving a middle substrate and a single wall corrugated product. In other embodiments the invention includes upper drive rollers, lower drive rollers and middle drive rollers for driving an upper substrate, a lower substrate and a middle substrate. The middle substrate is driven between the upper and lower substrates at a higher velocity to form flutes that are anchored between the upper an lower substrates thereby forming a corrugated product. The invention also provides for customized corrugated products having multiple fluted substrates in various desirable arrangements. Examples of such products include mattress, partition panels, other furniture and construction products.

The invention relates to a method for bonding two different plastics using a primer. The two plastics which are to be joined to each other have a weighted quadratic distance between the Hansen parameter (R.sub.a).sup.2 of more 22 MPa and the primer contains a polymer which has a weighted quadratic distance between the Hansen parameter (R.sub.a).sup.2 of less than 22 MPa to both of the plastics which are to be joined. The invention also relates to correspondingly bonded products.

The present invention relates to alternative methods of joining a solid part (1) and a polymer (2). The methods comprise attaching a primer layer (4) with a predetermined surface chemistry, density and thickness covalently to at least a part of a surface (3) of the solid part (1). Some embodiments of the invention further comprise polymerizing second molecules onto the primer layer (4) so that the surface (3) is at least partly covered with surface immobilized polymer brushes (8). The surface (3) of the solid part (1) is brought into contact with the polymer (2) and a predetermined temperature profile is applied resulting in covalent bonds (6) being established between the polymer (2) and the primer (4), and/or polymer brushes (8) melting or softening and entangling with melted or softened polymer (2) so that the solid part (1) and the polymer (2) remain joined after cooling. The obtained strength of the bonding between the solid part (1) and the polymer (2) is significantly higher than if the same materials are joined with conventional methods not comprising the establishment of a primer layer (4).

The invention relates to a process for bonding a silicone or silicone based material to a polyurethane and use of the bonded silicone-polyurethane in the manufacture of biomaterials, devices, articles or implants, in particular long term implantable medical devices in the fields of cardiology, orthopaedics, plastic surgery and gastroenterology. The process involves the steps of (a) flame treating a surface of the silicone or silicone based material and (b) bonding the polyurethane to the flame treated surface of the silicone or silicone based material.

A microfluidic device comprises a first substrate (102) made of a first polymer material and a second substrate (104) made of a second polymer material, the first (102) and second (104) substrates having respective bonding surfaces (23, 41), at least one of the bonding surfaces (41) having channel formations (14) so that, when the bonding surfaces (23, 41) are bonded by surface deformation to one another, the bonded first and second substrates (102, 104) and the channel formations (14) form at least part of a microfluidic channel network comprising a plurality of microfluidic channels, wherein one or more indicator pits (11), separate to the channel formations (14) defining the microfluidic channel network, are formed in at least one of the bonding surfaces (23, 41), so that surface deformation caused by the bonding process causes a change of configuration of the one or more indicator pits (11).

In a method for producing a filter medium, at least one substrate layer of a nonwoven comprising cellulose fibers and/or synthetic polymer fibers is provided and a fiber layer of polymer fibers is deposited on the at least one substrate layer. Prior to depositing the fiber layer, a solvent is applied to the at least one substrate layer, wherein a material of the substrate layer and/or a material of the fiber layer is soluble in the solvent. A filter medium produced by the method has material-fused connections at crossing points of the polymer fibers and/or cellulose fibers of the substrate layer with the polymer fibers of the fiber layer.

A microfluidic circuit element comprising a microfluidic main channel and nano interstices is disclosed. The nano interstices are formed at both sides of the main channel and are in fluid communication with the main channel. The nano interstices have a height less than that of the main channel, gives more driving force of the microfluidic channel and provides stable flow of a fluid. The microfluidic circuit element may be made from a plastic material having a contact angle of 90 degrees or less. The microfluidic circuit element is particularly useful when filling a liquid sample to the channel which is empty or filled with air and shows greatly improved a storage stability.

Described in one aspect is a multi-cell or multi-chambered container for sealing various materials such as therapeutic or diagnostic agents, animal or human tissue, tissue samples, specimens, blood, genetic material, or any other material. The container includes seals formed by folding the wall of the elongate body transverse to the interior of the elongate body and maintaining the folded wall portions adjacent one another or joining them together. In another aspect, the container disclosed may be made according to a method involving creating multiple seals at various locations along the elongate body thus creating sealed voids or cells between the seals within the elongate body.

A composite structural component includes a longitudinally extending elongated base element and a plurality of longitudinally extending elongated reinforcing members each secured to the base element along a length of the reinforcing member at spaced apart locations on the base element. The base element is of a first material having a first coefficient of thermal expansion and a first modulus of elasticity. The plurality of longitudinally extending elongated reinforcing members are of a second material having a second coefficient of thermal expansion less than the first coefficient of thermal expansion, and a second modulus of elasticity greater than the first modulus of elasticity, such that the composite structural component has an effective coefficient of thermal expansion in the longitudinal direction that is less than 25% of the first coefficient of thermal expansion.