A machine comprising: a flexible band (1) unwinding unit (11), a flexible band (1) folding unit (14), a drive unit (31) for moving the flexible band (1) in a forward movement direction (DA), a welding unit (16) and a laser beam cutting unit (53) for separating each individual flexible package from the flexible band (1) and for providing a fill opening in each flexible package by at least one fill opening cut, the laser beam cutting unit (53) having associated therewith a separator device, movable in a vertical direction and including an insertable separator element (41), interposed between the opposite faces of the folded flexible band (1), in an area adjacent to the fill opening (3), for separating the opposite faces of the flexible band (1) during cutting operations to prevent the fusion thereof.

Methods produce a three-dimensional dental block of material from a dental, polymerizable material. The methods include at least: transferring the polymerizable dental material into a radiolucent three-dimensional casting or press mold; irradiating the polymerizable dental material substantially from all sides with light in the UV/Vis spectral region forming polymerized outer surfaces of the dental material in the form of a solid outer shell of the dental material, wherein the shell is present in the defined three-dimensional geometry of the material whilst the inner region of the material is not polymerized or partially polymerized; heating the material with solid shell being present in defined three-dimensional geometry, to 60° C. to 150° C. for at least 90 minutes; and obtaining a dental, polymerized block of material having defined three-dimensional geometry.

A method of additive manufacturing of an object may include directing laser energy from a laser to a region for material deposition, extruding material using an extruder at the region of material deposition, sensing temperature within the region of the material deposition, and electronically controlling the laser energy using the temperature so as to sufficiently heat the region for material deposition prior to extruding the material to increase strength of the object. The method may include hardening or freezing extruded material through cooling in real-time.

Device surfaces are rendered superhydrophobic and/or superoleophobic through microstructures and/or nanostructures that utilize the same base material(s) as the device itself without the need for coatings made from different materials or substances. A medical device includes a portion made from a base material having a surface adapted for contact with biological material, and wherein the surface is modified to become superhydrophobic, superoleophobic, or both, using only the base material, excluding non-material coatings. The surface may be modified using a subtractive process, an additive process, or a combination thereof. The product of the process may form part of an implantable device or a medical instrument, including a medical device or instrument associated with an intraocular procedure. The surface may be modified to include micrometer- or nanometer-sized pillars, posts, pits or cavitations; hierarchical structures having asperities; or posts/pillars with caps having dimensions greater than the diameters of the posts or pillars.

A system/method allowing hydrophilicity alteration of a polymeric material (PM) is disclosed. The PM hydrophilicity alteration changes the PM characteristics by decreasing the PM refractive index, increasing the PM electrical conductivity, and increasing the PM weight. The system/method incorporates a laser radiation source that generates tightly focused laser pulses within a three-dimensional portion of the PM to affect these changes in PM properties. The system/method may be applied to the formation of customized intraocular lenses comprising material (PLM) wherein the lens created using the system/method is surgically positioned within the eye of the patient. The implanted lens refractive index may then be optionally altered in situ with laser pulses to change the optical properties of the implanted lens and thus achieve optimal corrected patient vision. This system/method permits numerous in situ modifications of an implanted lens as the patient's vision changes with age.

Biodegradable self-expanding polymer stent has an outer diameter of 0.25-40 mm, length of 5-250 mm, and closed-cell wall structure formed by struts, where ratio of inner diameter values before crimping and after crimping is in a range of 3 to 5, and made of a copolymer obtained from L-lactide, D-lactide, D,L-lactide, meso-lactide, glycolide, ε-caprolactone, trimethylene carbonate, p-dioxanone and compounds comprising functional groups capable of photopolymerization; supramolecular structure of the copolymer is oriented substantially circularly in a transversal cross section of the stent. Method of manufacturing includes extruding a tube of a polymer material; annealing the extruded polymer tube; laser cutting the extruded polymer tube to form a stent workpiece; heating the stent to above glass transition temperature of the polymer, crimping the stent workpiece uniformly over the entire outer surface thereof, and quenching at about minus 20 degrees Celsius; placing the quenched stent on a delivery means.

According to an example, in a method, a radiation source that is to output radiation at a preset energy level onto a surface of a three-dimensional (3D) printed object may be activated. In addition, the radiation source may be deactivated after a predefined period of time sufficient to cause an outer portion of about a predetermined thickness of the surface of the 3D printed object to begin to melt to finish the surface of the 3D printed object.

This invention relates to a container pre-cutting system, applicable to container forming machines (4) with laminar material (3) that provide intermittent advances to the laminar material with a length according to an advance step of the machine; said system being suitable for making a lower pre-cut (32) on the lower surface and an upper pre-cut (32) on the upper surface of the laminar material (3). The system comprises a lower pre-cutting device (1) by laser, with at least one laser head (15), and an upper pre-cutting device (2) by blade or by laser. The pre-cutting devices (1, 2) are separated in the advance direction of the laminar material (3) by a length equal to a multiple of the advance step of the machine.

A gasket includes a main body made of an elastic material, and a film laminated on the surface of the main body. The gasket has a film circumferential surface portion to be brought into contact with an inner peripheral surface of a syringe barrel, and an annular groove formed circumferentially of the film circumferential surface portion. The gasket further includes an annular member which is fixed in the annular groove and includes an annular projection projecting from the surface of the film.

In some examples, manufacturing techniques for implantable medical devices are described. An example method may including positioning a metal housing component adjacent to a polymer housing component so that there is an interface between the metal housing component and the polymer housing component; and forming a seal at the interface between the metal housing component and the polymer housing component to join the metal housing component and the polymer housing component, wherein the joined metal housing component and the polymer housing component form at least a portion of housing for the implantable medical device, wherein the housing of the implantable medical device contains electronic circuitry.