A peripheral intravenous catheter assembly may include a low-drag septum. The septum may include a body having a distal end and a proximal end, which may be sealed. The septum may include a slot disposed within an outer surface of the body and oriented along a longitudinal axis of the body. The slot may include a distal end spaced apart from the distal end of the body, and a proximal end spaced apart from the proximal end of the body. An introducer needle may extend through the slot.

A catheter system may include a catheter adapter, which may include a distal end, a proximal end, a lumen extending through the distal end and the proximal end, and a side port in fluid communication with the lumen. A catheter may extend distally from the catheter adapter. A septum may be disposed within the lumen. The septum may include a first slit generally aligned with a longitudinal axis of the catheter and a second slit offset from the longitudinal axis of the catheter. An introducer needle may be secured within a needle hub and may extend through the catheter and the first slit of the septum. A winged needle set may include: a body; a needle extending distally from the body and through the second slit of the septum; an extension tube extending from the body; and a blood collection device coupled to the extension tube.

A valve including an antimicrobial agent can be used with needleless access connectors. The valve can have an insert that includes an antimicrobial coating thereon and/or the valve can have physical features, such as a series of tunnels or groves or a patterned surface, containing an antimicrobial formulation and/or the valve can be made of a material that includes an antimicrobial agent.

The present invention relates to a multi-reservoir port, catheter, and non-coring needle system that supports high-flow applications such as hemodialysis and apheresis. In particular, the invention relates to improvements to provide optimal flow rates, septum life, and septum/needle stability when introducing fluid into the multi-reservoir port.

An apparatus for aseptic transfer of fluid therethrough. A first portion includes a closure and a piercing member comprising a hollow shaft for flowing fluid therethrough, and at least one port in fluid communication with the interior of the hollow shaft for passage of the fluid therethrough. The closure and/or the shaft is movable between (i) a first position wherein the closure closes the port(s), and (ii) a second position opening the port(s). A second portion includes a pierceable septum. The first and second portions are engageable such that the piercing member pierces the pierceable septum. When the pierceable member has at least partially penetrated the pierceable septum, the closure and/or the shaft moves from the first position to the second position for aseptical transfer of fluid.

Described is a low voltage, pulsed electrical stimulation device for reducing inflammation in a subject, which can be useful in the treatment of concussions, traumatic brain injury, cancer, and so forth.

Described are a system and method that utilize bioelectric signaling to balance electrical potentials in a subject's body via neuro-hormonal circuit loops, to increase elasticity of the subject's arteries to promote protein release to dampen arterial blood pressure, and to change arterial electrical charges to reduce narrowing of the arteries. The described system is designed to localize and stimulate the fibers inside the vagus nerve without inadvertent stimulation of non-baroreceptive fibers causing side effects like bradycardia and bradypnea. The system also controls release of specific proteins known to lower blood pressures including tropoelastin (known to increase elasticity in the aorta and other peripheral blood vessels).

A catheter assembly and/or an introducer may include one or more features configured to guide a probe and/or a catheter distally through a septum. The catheter assembly may include a catheter adapter and the septum. The catheter adapter may include a distal end, a proximal end, and a lumen extending therebetween. In some embodiments, the septum may be disposed within the lumen. The septum may include a proximal surface that is tapered inwardly in a distal direction such that the proximal surface of the septum is configured to guide the probe and/or the catheter distally through the septum. The catheter assembly may be configured to receive an introducer, which may include an introducer element. A proximal end of the introducer element may include another proximal surface that is tapered inwardly in the distal direction such that the other proximal surface is configured to guide the probe or the catheter distally through the septum.

Described is a skin regeneration therapy. The described therapy combines precise bioelectric signals, light, and biologics for skin treatment and regeneration. Precise bioelectric signals give clear instructions to the stimulated cell DNA/RNA to produce specific regenerative proteins on demand. Bioelectric signals give clear instructions to cell membranes on what to let in and what to let out and serve as an equivalent or surrogate of environmental stimuli to cause a cell action in response.

A needleless syringe connector cap to be provided to a container having an aperture at its top, said cap comprising an elastically deformable plastic valve body. Said valve body comprises a first and second passage, each passage extending through the valve body. Both passages comprise a cross-slit valve in the extreme lower end of said passage, embodied as an aeration valve. The first passage is adapted to receive a first tapered syringe tip and the second passage is adapted to receive a second tapered syringe tip, wherein when fluid is withdrawn from a container to which the cap is provided through the first (second) passage using a first (second) tapered syringe tip to which said first (second) passage is adapted, the second (first) cross-slit valve opens in response to an under pressure in said container resulting from said withdrawal, so as to aerate said container.