The disclosure relates to multilayer polymeric matrix based medical devices. In one example, a device comprises an inner first polymeric matrix and an outer second polymeric matrix. The addition of second polymeric matrix modifies bulk properties of each matrix thus resulting in a device where specific bulk properties are incorporated. The disclosure also relates to methods of manufacturing various embodiments of medical devices and their uses.

One embodiment of a contact lens includes a lens body configured to fit directly on the surface of the eye and legible characters positioned on the lens body. Another embodiment of a contact lens comprises a lens body including polymeric material and a lens enhancing material (e.g., ink, silicone material, medicament material, and the like) encapsulated in the polymeric material. The lens enhancing material can be in the form of isolated sections distributed in the surrounding polymeric material. Methods of making contact lenses include forming a first lens layer including a first surface, forming a pattern on the first surface, and forming a second lens layer over the pattern.

The invention relates to electronic contact lens systems, methods for fabrication thereof, and uses thereof for treatment of ophthalmic diseases and conditions, for example, meibomian gland dysfunction.

A biomedical device including an energy source, an electro-active device operatively connected to the energy source, circuitry configured to control operation of the electro-active device, at least one barrier layer including at least one inorganic material surrounding the energy source, electro-active device and circuitry, and at least one molded layer surrounding the at least one barrier layer. A method for encapsulating electronic components of an electro-active biomedical device in a protective envelope containing a barrier layer including at least one inorganic compound, and a molded polymer overcoat.

A method for determining whether or not a single use mold is acceptable, comprises providing a closed lens mold (1) comprising two lens mold halves, and having a first and a second optical lens molding surface forming a molding cavity (15) and defining a molding cavity thickness therebetween, providing at least one interferometer (3), each having at least one thickness measurement beam (31), providing a lens mold holder (2), positioning the lens mold (1) such that the thickness measurement beam (31) of the interferometer (3) impinges on the lens mold (1) for measurement of the distance between the two molding surfaces surrounding the molding cavity (15), measuring the thickness profile of the molding cavity (15) with the interferometer (3) on at least three positions of the molding cavity (15) of the lens mold (1), comparing the measured thickness profile with a predetermined thickness profile to determine whether or not the lens mold (1) is acceptable.

Aspects of the disclosure provide for a method of creating a lens. Examples of the method include identifying a limbal zone of the eye, determining a back optic zone within the limbal zone, determining a front optic zone based at least partially on the limbal zone, computing a lens surface of the lens based at least partially on the limbal zone, the back optic zone, and the front optic zone, de-centering at least one of the back optic zone or the front optic zone from a visual axis or a spindle axis of the lens.

One embodiment of a rigid gas permeable ocular lens may be formed by a process including forming a portion of a mold including a first side having a profile shaped to form an anterior surface of the rigid gas permeable ocular lens, applying a liquid lens material to the first side of the portion of the mold, and at least partially curing the liquid lens material to form the rigid gas permeable ocular lens. Methods of forming molds for rigid gas permeable ocular lenses, including molds for casting rigid gas permeable ocular lenses having a desired surface smoothness and desired dimensional tolerances are also provided.

Ophthalmic lenses and methods of manufacture thereof are disclosed. The ophthalmic lenses include metasurface features that define a metasurface array on a lens body. The metasurface array can be tuned to modify an optical property, such as glare reduction, of the ophthalmic lens using an arrangement of metasurface building elements dimensioned from an optical wavelength, including being dimensioned smaller than an optical wavelength. The ophthalmic lenses can be subject to physical manipulation, including rolling or other folding during an installation procedure, and as such, the modified optical property induced by the metasurface array can be maintained after such manipulation. The ophthalmic lenses can be formed using a molding process, in which the metasurface array is associated with a non-solid material and formed into a lens shape with the material.

The present invention relates to a method of manufacturing a contact lens including the steps of: (i) adding reactive components to a mold, wherein the reactive components comprise (a) at least one hydroxy-containing silicone component having a weight average molecular weight from about 200 to about 15,000 g/mole and (b) at least one mono-ether terminated, mono-methacrylate terminated polyethylene glycol having a weight average molecular weight from about 200 to about 10,000 g/mole; (ii) curing the reactive components within the mold to form the contact lens; and (iii) removing the contact lens from said mold.

A method for making a hydrogel, photochromic contact lens including supplying a first lens composition comprising a contact lens monomer and a photochromic material to a front contact lens mold and supplying a second lens composition to said contact lens mold wherein the viscosity of said first composition is at least about 1000 cp greater than the viscosity of said second contact lens composition, and the makeup of said second composition matches the of said first composition to reduce strain between said compositions of the resulting lens.