The present disclosure provides extruded PTFE composite tubes with a reduced coefficient of friction (COF). In some embodiments, such extruded PTFE composite tubes may exhibit a reduced change in coefficient of friction between about 20° C. and about 40° C. with the inclusion of secondary polymeric particles with small particle sizes (<100 μm) at loading percentages of less than about 50 weight %.

An organ preservation and/or perfusion solution for an isolated tissue or organ is provided. The solution comprises dextran, glucose, calcium ions, a buffer, and water, has a pH of 6.6 to 7.8, and is sterile based on having been subjected to heat sterilization. A method of preparing the solution also is provided. The method comprises combining dextran, glucose, calcium ions, buffer, and water to obtain an initial solution, adjusting the pH of the initial solution to 7.0 to 7.8 if needed, and subjecting the initial solution to heat sterilization, thereby obtaining the organ preservation and/or perfusion solution. A method of preserving and/or perfusing an isolated tissue or organ also is provided. A method for flushing, storage, and/or transportation of an isolated lung after removal from a donor in preparation for eventual transplantation into a recipient also is provided.

An organ preservation and/or perfusion solution for an isolated tissue or organ is provided. The solution comprises dextran, glucose, calcium ions, a buffer, and water, has a pH of 6.6 to 7.8, and is sterile based on having been subjected to heat sterilization. A method of preparing the solution also is provided. The method comprises combining dextran, glucose, calcium ions, buffer, and water to obtain an initial solution, adjusting the pH of the initial solution to 7.0 to 7.8 if needed, and subjecting the initial solution to heat sterilization, thereby obtaining the organ preservation and/or perfusion solution. A method of preserving and/or perfusing an isolated tissue or organ also is provided. A method for flushing, storage, and/or transportation of an isolated lung after removal from a donor in preparation for eventual transplantation into a recipient also is provided.

A tube received, at least in part, by a breastmilk warmer includes a first segment having a first thermal conductivity, a second segment having a second thermal conductivity different from the first thermal conductivity, and a third segment having a third thermal conductivity different from at least one of the first and second thermal conductivities. The first segment is configured to be coupled to a source of fluid. The second segment is fluidly coupled to the first segment and disposed in a labyrinthine manner within a breastmilk warmer. The third segment is fluidly coupled to the second segment and is configured to be coupled to a feeding apparatus. The tube also includes a fluid lumen extending from the first segment through the second segment and to the third segment. The fluid lumen has a uniform diameter from the first segment to the third segment.

A method of controlling flow through a flexible tube includes providing a pinch clamp mechanism including a pinching element and a pinching surface configured to apply a force on the flexible tube when the flexible tube is positioned between the pinching element and the pinching surface. The method also includes displacing the pinching element relative to the pinching surface with a mechanical drive unit and biasing the pinching element toward the pinching surface with a spring.

An apparatus is provided for connecting and disconnecting a tubular fitting connector to a fluid conduit. A cradle assembly accommodates the fluid conduit, and includes a body having a first port and a second port. The first and second ports are disposed at opposite ends of the body, and each port is configured for receiving an end cap of the tubular fitting to fasten or unfasten the end cap for replacement. A connector holder is disposed between the first and second ports, and is configured for accommodating insertion of the connector. A holder assembly is provided for accommodating insertion of the tubular fitting. The cradle assembly is reciprocable relative to the holder assembly for transitioning the cradle assembly between a first position, a second position, and a third position.

An extension set may include a clamp, which may include a housing and an actuator. The actuator may be movable between a raised position and a depressed position with respect to the housing. The actuator may include a bump profile. The extension set may include an extension tube, which may be disposed within the housing. The extension tube may include a loop. In response to movement of the actuator between the raised position and the depressed position with respect to the housing, the bump profile may progressively clamp the extension tube along the loop. The loop may facilitate an increased fluid volume flowing distally towards a catheter in response to actuating the clamp.

An extension set may include a clamp, which may include a housing and an actuator. The actuator may be movable between a raised position and a depressed position with respect to the housing. The actuator may include a bump profile. The extension set may include an extension tube, which may be disposed within the housing. The extension tube may include a loop. In response to movement of the actuator between the raised position and the depressed position with respect to the housing, the bump profile may progressively clamp the extension tube along the loop. The loop may facilitate an increased fluid volume flowing distally towards a catheter in response to actuating the clamp.

The disclosed packaging bags may include a flexible front sidewall and a flexible rear sidewall with at least a first closed edge, second closed edge, and third closed edge coupling the front sidewall to the rear sidewall. A perforation may be formed through the flexible front sidewall and the flexible rear sidewall along the first closed edge. The perforation may extend in a first segment from the first closed edge toward a central region of the packaging bag, in a second segment in a direction along the first closed edge, and in a third segment back to the first closed edge. The second segment may include at least one elongated ventilation slit. Various other related packaging bags and methods are also disclosed.

A line mount includes a treatment machine having a housing and one or more magnets or ferromagnetic elements mounted thereon, a line holder having at least one complementary one of magnets and ferromagnetic elements such as to cause the line holder to be attachable magnetically to the housing. The one or more magnets or ferromagnetic elements being numbered and arranged to permit the line holder to be supported thereby in multiple positions and orientations relative to the housing.