Systems and methods for pumping milk from a breast, wherein the milk is expressed from the breast under suction and milk is expulsed from the pumping mechanism to a collection container assembly.

A guiding sheath has a braided layer for improved deflection characteristics and ring electrodes for electrical sensing, mapping and visualization, wherein lead wires for the ring electrodes are passed through lumened tubing position under the braided layer in a proximal portion of the guiding sheath shaft and above the braided layer in a distal portion of the guiding sheath shaft. Moreover, the hemostatic valve includes an improved friction ring with air vents to reduce the risk of air being introduced into the valve.

The invention relates to an extracorporeal blood treatment device comprising a hydraulic system II comprising a plurality of flow paths, the blood treatment device having a control unit 40 which provides an operating mode for disinfecting the hydraulic system with a liquid which can be supplied via one of the flow paths. Moreover, the invention relates to a method for operating an extracorporeal blood treatment device with a hydraulic system comprising a plurality of flow paths. The blood treatment device according to the invention is characterized in that the hydraulic system II has a valve device 23 which provides several switching positions. The valve device 23 has an inlet 25A for the liquid for disinfecting the hydraulic system and a plurality of outlets 26A, 27A, 28A, wherein in a switching position the inlet 25A is connected to one of the outlets 26A, 27A, 28A and in another switching position the inlet is connected to a plurality of outlets 26A, 27A, 28A. The inlet 25A of the valve device 23 is in fluid communication with the flow path via which liquid for disinfecting the hydraulic system II can be supplied, and the outlets 26A, 27A, 28A of the valve device 23 are in fluid communication with another flow path of the hydraulic system, so that liquid can simultaneously be supplied to the individual flow paths.

The invention relates to a sprayable liquid solution for the transdermal delivery of testosterone comprising testosterone, a penetration enhancer, and a film forming excipient, and to methods of treatment using this composition.

The invention relates to a sprayable liquid solution for the transdermal delivery of testosterone comprising testosterone, a penetration enhancer, and a film forming excipient, and to methods of treatment using this composition.

A valve is provided for a sheath, catheter, or other tubular device that includes a first face, a second face opposite the first face and an axis extending between the first and second faces. A first slit extends substantially parallel to the axis from the first face towards the second face to a first intermediate location within the valve body, a second slit extends substantially parallel to the axis from the second face towards the first face to a second intermediate location within the valve body, and a bore extends along the axis between the first intermediate location and the second intermediate location.

A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes in a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

A gas elimination apparatus and a method for use in an intravenous delivery system are provided. The apparatus includes in a fluid inlet coupling a fluid flow into a liquid chamber, a fluid outlet protruding into the liquid chamber, and a flow diversion member proximal to the fluid outlet. The flow diversion member configured to block a direct flow between the fluid inlet and the fluid outlet. The apparatus includes a membrane separating a portion of the liquid chamber from an outer chamber and a gas venting valve fluidically coupling the outer chamber with the atmosphere. The flow diversion member may be mechanically supported by at least one strut or elongate member extending along a flow direction into the liquid chamber.

In general, medical sheath systems that include a curved support sheath are described. In one embodiment, the support sheath includes a curved tube includes a distal portion fixed in an orientation perpendicular to the proximal end during advancement of an interventional tool through the support sheath.

The invention provides a drug mixing and injection system, in particular an adapter for said system enabling the preparation of drug formulations. In a first aspect, the invention relates to an adapter for a drug mixing and injection system comprising a first subunit (110) adapted to hold a vial (113) and a reservoir (115) with injectable liquid, a second subunit (120) comprising a valve (115) and an outlet port (122), at least one internal adapter channel (131), a first cannula (134) between the vial (113) and the internal adapter channel (131), wherein the adapter (100) has a resting position and an activated position. In another aspect, the invention relates to a drug mixing and injection system (200) comprising the adapter of the first aspect of the invention, a vial and a reservoir with injectable liquid. In a further aspect, the invention relates to a method of preparing an injectable drug formulation by use of the drug mixing and injection system (200) of the above mentioned aspect of the invention comprising activation of the system and transferring an injectable liquid from the reservoir to the vial, mixing the drug and transfer the resulting injectable drug formulation back to the reservoir, bringing the valve to a second position and transferring the injectable drug formulation to the outlet port.