Provided is a chamber configuration for a reverse flow centrifuge, and a reverse flow centrifuge system configured for low fluid volume and small radius rotation. The compact reverse flow centrifuge system has a reusable subsystem and a single use replaceable subsystem. The replaceable subsystem comprises a separation chamber, fluid delivery manifold and rotational mounting connecting the separation chamber to the fluid manifold. The single use replaceable subsystem provides a closed environment for execution of reverse flow centrifugation processes. The separation chamber has a substantially conical fluid enclosure portion connected to a neck portion, and a dip tube extends centrally through the conical fluid enclosure to provide a fluid path to the tip of the conical fluid enclosure.

A method and a device for the measurement of one or more fluid-mechanically effective parameters of a fluid, with a fluid pump which comprises a delivery element which is mounted in a magnet bearing, and the delivery element of the fluid pump is excited into an oscillation by way of an excitation device, wherein the oscillation parameters as well as, as the case may be, the oscillation behaviour is measured, and parameters of the fluid are determined from this.

A method and a device for the measurement of fluid-mechanically effective parameters of a fluid, with a fluid pump which comprises a delivery element (2) which is mounted in a magnet bearing (10, 10a, 11, 11a), according to the invention, envisages the delivery element (2) of the fluid pump being excited into an oscillation by way of an excitation device (16, 44), wherein the oscillation parameters as well as, as the case may be, the oscillation behavior is measured, and parameters of the fluid are determined from this.

A pump, such as a blood pump, includes a pump chamber with a wall and a fluid connection between an inlet and an outlet, along with an impeller, a motor stator, and a control coil arranged on the pump chamber for exerting, together with first rotor magnets, a controllable axial force on the rotor. A control unit provides a control current for the control coil, in order to hold the rotor in a position which is spaced apart axially from the wall of the pump chamber. A first chamber magnet is arranged close to the winding of the control coil and opposite the first rotor magnet, in order to provide, together with the first rotor magnet, a force between the first rotor magnet and the first chamber magnet, and in order to orient the rotor relative to the wall of the pump chamber.

A pump, such as a blood pump, includes a pump chamber with a wall and a fluid connection between an inlet and an outlet, along with an impeller, a motor stator, and a control coil arranged on the pump chamber for exerting, together with first rotor magnets, a controllable axial force on the rotor. A control unit provides a control current for the control coil, in order to hold the rotor in a position which is spaced apart axially from the wall of the pump chamber. A first chamber magnet is arranged close to the winding of the control coil and opposite the first rotor magnet, in order to provide, together with the first rotor magnet, a force between the first rotor magnet and the first chamber magnet, and in order to orient the rotor relative to the wall of the pump chamber.

A method for conveying blood or priming liquid as a medium using a blood pump, measures gas in the medium in a feed line to the pump, in or on the pump, and the pump power is increased only for a short time as a function of the measured gas. A blood pump, in particular a centrifugal pump or diagonal pump, includes a rotor, a housing and a drive, the pump including a gas detector which acts upon the drive when gas is detected.

An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.

An apparatus for locating and venting pathogen cells in blood. A cassette has a plurality of thin holding chambers that are filled with blood drawn from a patient. A light source illuminates each of the holding chambers and passes light to an underlying sensor array such that the cells in the blood produce shadow images of the cells in the sensor array. A processor performs pattern recognition to identify and locate the pathogen cells by use of an image library. After the pathogen cells are located, a pump is operated to move the identified cells to a processing zone. When each identified cell reaches the processing zone, a control voltage is generated to open a valve to vent the identified pathogen cells. The pump refills the cassette holding chambers, returns the processed blood to the patient, and the procedure is repeated for a treatment time period.

The present invention provides an intravascular blood pump system with an external motor and comprising an impeller housing and/or impeller blade(s) that may be expandable and collapsible. The blade(s) and/or impeller housing may be biased to expand or may be expanded by centrifugal forces generated during rotation of the impeller and blades an operatively connected rotational external motor.

Various aspects of the present disclosure are directed toward apparatuses, systems, and methods that may include an inflow or outflow cannula apparatus.