This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device system for treating a heart, includes a control system including a processor and a pump, a hub coupled to the control system, a control system including a processor and a pump, a hub coupled to the control system, a first catheter shaft having a first lumen and a first end coupled to the hub, a second catheter shaft extending within the first lumen and having a first end couple to the hub, a first expandable member disposed on the first catheter shaft, wherein the first expandable member is configured to be positioned in the superior vena cava and a second expandable member disposed on the second catheter shaft distal to the first expandable member, wherein the second expandable member is configured to translate relative to the first expandable member.

This disclosure provides design, material, manufacturing method, and use alternatives for medical devices. An example medical device system for treating a heart includes a control system including a display unit. Further, the display unit is configured to display a first visual representation of a first medical device disposed in a first anatomical location, a second visual representation of a second medical device disposed in a second anatomical location, a third visual representation of a first physiological parameter, wherein the first physiological parameter is measured by a first sensor disposed at a first location proximate the first medical device and a fourth visual representation of a second physiological parameter, wherein the second physiological parameter is measured by a second sensor disposed at a second sensor location proximate the second medical device.

Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, an intravascular propeller is installed into the descending aorta and anchored within via an expandable anchoring mechanism. The propeller and anchoring mechanism may be foldable so as to be percutaneously deliverable to the aorta. The propeller may have foldable blades. The blades may be magnetic and may be driven by a concentric electromagnetic stator circumferentially outside the magnetic blades. The stator may be intravascular or may be configured to be installed around the outer circumference of the blood vessel. The support may create a pressure rise between about 20-50 mmHg, and maintain a flow rate of about 5 L/min. The support may have one or more pairs of contra-rotating propellers to modulate the tangential velocity of the blood flow. The support may have static pre-swirlers and or de-swirlers. The support may be optimized to replicate naturally occurring vortex formation within the descending aorta.

A system and method for increasing the speed of blood and the wall shear stress in a peripheral artery or peripheral vein to a sufficient level and for a sufficient period of time to result in a persistent increase in the overall diameter and lumen diameter of the artery or vein is provided. The method includes systems and methods to effect the movement of blood at the desired rate and in the desired direction. The movement of blood is monitored and adjusted, as necessary, to maintain the desired blood speed and wall shear stress in the peripheral artery or vein in order to optimize the rate and extent of persistent diameter increase of the peripheral artery or peripheral vein.

A system is used to access and treat a carotid artery. The system includes an arterial access device that receives blood flow from the common carotid artery via a distal region of the arterial access device. A shunt fluidly connects to the arterial access device and defines a blood flow pathway for blood to flow from the arterial access device to a return site. A flow control assembly assists blood flow through the shunt and includes a pump having at least one roller that interacts with the tubing of the shunt to pump blood through the shunt toward the return site.

A system is used to access and treat a carotid artery. The system includes an arterial access device that receives blood flow from the common carotid artery via a distal region of the arterial access device. A shunt fluidly connects to the arterial access device and defines a blood flow pathway for blood to flow from the arterial access device to a return site. A flow control assembly assists blood flow through the shunt and includes a pump having at least one roller that interacts with the tubing of the shunt to pump blood through the shunt toward the return site.

Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports. The supports may create a pressure rise between about 40-80 mmHg, and maintain a flow rate of about 5 L/min. The support may be configured to be inserted in a collinear manner with the descending aorta. The support may be optimized to replicate naturally occurring vortex formation within the aorta. Diffusers of different dimensions and configurations, such as helical configuration, and/or the orientation of installation may be used to optimize vortex formation. The support may use an impeller which is electromagnetically suspended, stabilized, and rotated to pump blood.

Mechanical circulatory supports configured to operate in series with the native heart are disclosed. In an embodiment, a centrifugal pump is used. In an embodiment, inlet and outlet ports are connected into the aorta and blood flow is diverted through a lumen and a centrifugal pump between the inlet and outlet ports. The supports may create a pressure rise between about 40-80 mmHg, and maintain a flow rate of about 5 L/min. The support may be configured to be inserted in a collinear manner with the descending aorta. The support may be optimized to replicate naturally occurring vortex formation within the aorta. Diffusers of different dimensions and configurations, such as helical configuration, and/or the orientation of installation may be used to optimize vortex formation. The support may use an impeller which is electromagnetically suspended, stabilized, and rotated to pump blood.

A pump blood flow determination method and apparatus for a blood pump, an electronic device, and a storage medium. The method comprises: (S110) obtaining a first correspondence between absolute values of first current differences and first pump blood flow values at different rotational speeds of the blood pump in an in vitro test simulation environment; (S120) obtaining first reference current values of current cycles at different rotational speeds of the blood pump in an actual human body environment of a test object; (S130) for the current cycles at the different rotational speeds, calculating differences between the first reference current values and current values at different moments within the current cycles, so as to obtain an absolute value of at least one second current difference.

Methods are provided for effectively distinguishing the abilities of a human liver and an extracorporeal liver in an extracorporeal liver perfusion system to extract cholate and, thus, measure relative liver function.