Catheter blood pumps that include an expandable conduit coupled to at least one hub shaped to promote smooth blood flow. In some examples, the at least one hub includes non-metallic configuration and the struts comprise a metallic configuration (e.g., nitinol). The hub can include one or more layers, including a combination of Chronoflex and Pebax.

A percutaneously insertable blood pump assembly comprises a pump section, a catheter attached to a proximal end of the pump section, a first apertured section distal to the pump section and in fluid communication therewith, a cannula affixed to and in fluid communication with the first apertured section, and a second apertured section distal to the cannula and in fluid communication therewith. One of the first and second apertured section is a blood outlet from the cannula. The blood outlet has a body portion, an apertured portion, and a ring portion. The plurality of struts in the apertured portion extend from and join the body portion to the ring portion. The struts are asymmetric along at least a portion of their length from the body portion of the outlet to the ring portion of the outlet.

A percutaneously insertable blood pump assembly comprises a pump section, a catheter attached to a proximal end of the pump section, a first apertured section distal to the pump section and in fluid communication therewith, a cannula affixed to and in fluid communication with the first apertured section, and a second apertured section distal to the cannula and in fluid communication therewith. One of the first and second apertured section is a blood outlet from the cannula. The blood outlet has a body portion, an apertured portion, and a ring portion. The plurality of struts in the apertured portion extend from and join the body portion to the ring portion. The struts are asymmetric along at least a portion of their length from the body portion of the outlet to the ring portion of the outlet.

A percutaneous circulatory support device including a percutaneous blood pump coupled to a distal end region of an elongate shaft at a junction. The percutaneous blood pump includes a flexible cannula, an impeller housing, and a motor housing. The percutaneous blood pump is configured to pump blood through a housing of the percutaneous blood pump during use. A drug eluting coating is disposed on at least a portion of a surface of the percutaneous blood pump.

A percutaneous circulatory support device including a percutaneous blood pump coupled to a distal end region of an elongate shaft at a junction. The percutaneous blood pump includes a flexible cannula, an impeller housing, and a motor housing. The percutaneous blood pump is configured to pump blood through a housing of the percutaneous blood pump during use. A drug eluting coating is disposed on at least a portion of a surface of the percutaneous blood pump.

Provided are a driving mechanism and a blood pump. The driving mechanism comprises a housing, a rotating shaft, a rotor, a first shaft sleeve, a second shaft sleeve, and a stopping member. The rotating shaft is rotatably mounted on the housing. The rotating shaft has a connecting end and a ball head end away from the connecting end. The connecting end is configured to be connected to an impeller. The rotor is fixedly connected to the rotating shaft. The first shaft sleeve is provided with a groove. The rotating shaft is rotatably arranged on the second shaft sleeve in a penetrating manner. The ball head end is movably arranged in the groove. The stopping member is fixedly connected to at least one of the rotating shaft and the rotor. The stopping member can abut against the second shaft sleeve.

Provided are a driving mechanism and a blood pump. The driving mechanism comprises a housing, a rotating shaft, a rotor, a first shaft sleeve, a second shaft sleeve, and a stopping member. The rotating shaft is rotatably mounted on the housing. The rotating shaft has a connecting end and a ball head end away from the connecting end. The connecting end is configured to be connected to an impeller. The rotor is fixedly connected to the rotating shaft. The first shaft sleeve is provided with a groove. The rotating shaft is rotatably arranged on the second shaft sleeve in a penetrating manner. The ball head end is movably arranged in the groove. The stopping member is fixedly connected to at least one of the rotating shaft and the rotor. The stopping member can abut against the second shaft sleeve.

A cardiac assist system includes a pneumatic effector and an external drive unit. The pneumatic effector is implanted proximate a patient's heart to enhance left ventricular contraction. The external drive unit includes a gas pump connectable to the pneumatic effector and is configured to actuate the pneumatic effector assembly in response to the patient's sensed heart rhythm. The system may include an isolation valve located between the gas pump assembly and an inlet to the pneumatic effector and a pressure sensor located between the isolation valve and the inlet to the pneumatic effector, where the control circuitry is configured to receive changes in pressure sensed by the pressure sensor the when the isolation valve is closed to isolate the pneumatic effector. The system may also include a liquid accumulator and a liquid sensor adjacent the liquid accumulator sensor to detect liquid in the pneumatic effector.

A cardiac assist system includes a pneumatic effector and an external drive unit. The pneumatic effector is implanted proximate a patient's heart to enhance left ventricular contraction. The external drive unit includes a gas pump connectable to the pneumatic effector and is configured to actuate the pneumatic effector assembly in response to the patient's sensed heart rhythm. The system may include an isolation valve located between the gas pump assembly and an inlet to the pneumatic effector and a pressure sensor located between the isolation valve and the inlet to the pneumatic effector, where the control circuitry is configured to receive changes in pressure sensed by the pressure sensor the when the isolation valve is closed to isolate the pneumatic effector. The system may also include a liquid accumulator and a liquid sensor adjacent the liquid accumulator sensor to detect liquid in the pneumatic effector.

Blood pump systems such as percutaneous ventricular assist devices (pVADs) can be used to provide hemodynamic support to patients. Some embodiments of pVADS include an inlet cannula and a pump housing. The inlet cannulae and pump housings of example pVADs may be reconfigurable between a low-profile delivery configuration and a radially expanded operable configuration. In some embodiments, a pusher rod is used to releasably apply axial tension to the inlet cannulae and pump housings to thereby configure those components in the low-profile delivery configuration.