Blood pump systems such as percutaneous ventricular assist devices (pVADs) can be used to provide hemodynamic support to patients. Some embodiments of pVADS include an inlet cannula and a pump housing. The inlet cannulae and pump housings of example pVADs may be reconfigurable between a low-profile delivery configuration and a radially expanded operable configuration. In some embodiments, a pusher rod is used to releasably apply axial tension to the inlet cannulae and pump housings to thereby configure those components in the low-profile delivery configuration.

A ventricular assist system including a cannula that defines a lumen and includes a first end and a second end. The second end of the cannula includes a tip that defines an opening, and a pump operably is coupled to the first end of the cannula. A pump anchor is operably coupled to the pump. The pump anchor has a retracted position and a deployed position. A tip anchor is operably coupled to the second end of the cannula proximate the tip. A sheath is selectively disposed around the cannula, and a guidewire disposed within the lumen of the cannula.

A ventricular assist system including a cannula that defines a lumen and includes a first end and a second end. The second end of the cannula includes a tip that defines an opening, and a pump operably is coupled to the first end of the cannula. A pump anchor is operably coupled to the pump. The pump anchor has a retracted position and a deployed position. A tip anchor is operably coupled to the second end of the cannula proximate the tip. A sheath is selectively disposed around the cannula, and a guidewire disposed within the lumen of the cannula.

A stabilization device for securing a catheter within cardiovascular system of a patient. The stabilization device includes a base defining a skin contacting surface, and a ladder-lock coupled to the base. The ladder-lock includes a pair of rails and one or more rungs extending between the rails, each of the rails being pivotably attached to the base such that the ladder-lock is pivotable from an unlocked position in which the catheter is slidable within the cardiovascular system of the patient and a locked position in which the catheter is fixed relative to the cardiovascular system.

An access device for a heart chamber, a removable hemostatic valve unit, and a system including a cardiac assist unit are disclosed. In examples, the access device includes an apical base plate and a sealing unit configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.

A ventricular assist system including a cannula that defines a lumen and includes a first end and a second end. The second end of the cannula includes a tip that defines an opening, and a pump operably is coupled to the first end of the cannula. A pump anchor is operably coupled to the pump. The pump anchor has a retracted position and a deployed position. A tip anchor is operably coupled to the second end of the cannula proximate the tip. A sheath is selectively disposed around the cannula, and a guidewire disposed within the lumen of the cannula.

A ventricular assist system including a cannula that defines a lumen and includes a first end and a second end. The second end of the cannula includes a tip that defines an opening, and a pump operably is coupled to the first end of the cannula. A pump anchor is operably coupled to the pump. The pump anchor has a retracted position and a deployed position. A tip anchor is operably coupled to the second end of the cannula proximate the tip. A sheath is selectively disposed around the cannula, and a guidewire disposed within the lumen of the cannula.

A medical system can include: a pump disposed along a longitudinal axis of the blood flow assist system and comprising an impeller disposed in a pump housing; a power lead coupled with a first end portion of the pump; and a tether coupled with a second end portion of the pump opposite to the first end portion. During operation of the blood flow assist system with the pump disposed within a blood vessel, the power lead can be configured to extend from within the blood vessel within which the pump is disposed to outside a first vascular access site to couple to a control system and the tether can be configured to extend from within the blood vessel within which the pump is disposed to an anchoring location disposed away from the second end portion.

A medical system can include: a pump disposed along a longitudinal axis of the blood flow assist system and comprising an impeller disposed in a pump housing; a power lead coupled with a first end portion of the pump; and a tether coupled with a second end portion of the pump opposite to the first end portion. During operation of the blood flow assist system with the pump disposed within a blood vessel, the power lead can be configured to extend from within the blood vessel within which the pump is disposed to outside a first vascular access site to couple to a control system and the tether can be configured to extend from within the blood vessel within which the pump is disposed to an anchoring location disposed away from the second end portion.

An access device for a heart chamber, a removable hemostatic valve unit, and a system and a method of creating a transapical passage on a beating heart are disclosed. In examples, the access device (1) includes an apical base plate (100) and a sealing unit (3) configured to provide a separation of a wet zone from a heart chamber and a dry zone with a gaseous environment outside of said heart chamber inside a patient body at the same time.