A therapy system configured to wash out or flush out the oral and/or nasal cavity to reduce the effective dead space and reduce the work of breathing. The system may displace the expired air in the oral and/or nasal cavity with atmospheric air, or air with altered concentrations, for example, increased humidity, or oxygen levels. A sealed oral interface is provided to the mouth of a patient to supply a volume of pressurized gas. A control system to synchronize the supply of pressurized gas with the patients respiratory cycle. The supply of respiratory gas may be provided during only a portion of the respiratory cycle.

An extension assembly for a catheter having an extension tube, an extension connector and an indicator assembly. The extension tube has a proximal end and a distal end, and, an inner bore. The extension connector has a body with a central bore, with the proximal end of the extension tube coupled to a first end of the body. The extension connector further includes a slot in the body defined by lower end wall and upstanding walls extending therefrom, terminating at an upper opening. A radial passage extends from the central bore to the at least one slot. The indicator assembly has an indicator that is structurally configured to change color in the presence of a chemical indicative of a bladder infection. A wicking member is in fluid communication with the radial passage and the indicator, with the wicking member being positioned between the radial passage and the indicator.

An extension assembly for a catheter comprises an extension tube, an extension connector, and an indicator assembly. The extension tube has a proximal end and a distal end. The extension tube further has an inner bore and an opening placing an interior of the extension tube in fluid communication with an exterior of the extension tube. The extension connector is coupled to the proximal end of the extension tube. The indicator assembly is comprised of a sealing member, a wicking member, and an indicator. The sealing member including a first side and a second side. The wicking member includes a wicking tab to be disposed within the opening of the extension tube. The indicator is in fluid communication with the wicking member. The sealing member is at least partially clear to allow visual inspection of the indicator once the indicator assembly is coupled to the extension tube.

A method for capturing dislodged vegetative growth during a surgical procedure is provided. The method includes maneuvering, into a circulatory system, a first cannula having a distal end and an opposing proximal end, such that the first cannula is positioned to capture the vegetative growth en bloc. A second cannula is positioned in fluid communication with the first cannula, such that a distal end of the second cannula is situated in spaced relation to the distal end of the first cannula. A suction force is provided through the distal end of the first cannula so as to capture the vegetative growth. Fluid removed by the suction force is reinfused through the distal end of the second cannula. Subsequent to becoming dislodged, the vegetative growth is captured by the first cannula. A method for capturing a vegetative growth during removal of a pacemaker lead is also provided.

A system includes a respiratory device, a mask, a microphone, a speaker, and a control system. The respiratory device is configured to supply pressurized air. The mask is coupled to the respiratory device and configured to engage a user during a sleep session to aid in directing the supplied pressurized air to the user. The microphone is configured to generate audio data. The speaker is configured to emit sound. The control system is configured to analyze the audio data to determine if noise associated with air leaking from the mask is occurring. Responsive to (i) the analysis resulting in a determination that noise associated with air leaking from the mask is occurring, (ii) the respiratory device determining that air is leaking from the mask, or (iii) both, the speaker is caused to emit the sound to aid in masking the noise associated with the air leaking from the mask.

A system includes a respiratory device, a mask, a microphone, a speaker, and a control system. The respiratory device is configured to supply pressurized air. The mask is coupled to the respiratory device and configured to engage a user during a sleep session to aid in directing the supplied pressurized air to the user. The microphone is configured to generate audio data. The speaker is configured to emit sound. The control system is configured to analyze the audio data to determine if noise associated with air leaking from the mask is occurring. Responsive to (i) the analysis resulting in a determination that noise associated with air leaking from the mask is occurring, (ii) the respiratory device determining that air is leaking from the mask, or (iii) both, the speaker is caused to emit the sound to aid in masking the noise associated with the air leaking from the mask.

Various implementations include a CPAP alarm system that generates an alarm when the concentration of CO.sub.2 is less than a certain threshold. The threshold may represent a minimum concentration of CO.sub.2 that is expected to be expelled from the patient. Other implementations are directed to a CPAP apparatus that can couple the CPAP alarm system to a CPAP air delivery device. The CPAP apparatus includes a support body that can be coupled to the CPAP air delivery device and that supports the CPAP alarm system outside of the air delivery device. A CO.sub.2 concentration sensor of the CPAP alarm system can be disposed on the apparatus such that the flow of CO.sub.2 from a breathing patient is directed toward the CO.sub.2 concentration sensor when the CPAP air delivery device is in use and is in the proper position for the patient.

Various implementations include a CPAP alarm system that generates an alarm when the concentration of CO.sub.2 is less than a certain threshold. The threshold may represent a minimum concentration of CO.sub.2 that is expected to be expelled from the patient. Other implementations are directed to a CPAP apparatus that can couple the CPAP alarm system to a CPAP air delivery device. The CPAP apparatus includes a support body that can be coupled to the CPAP air delivery device and that supports the CPAP alarm system outside of the air delivery device. A CO.sub.2 concentration sensor of the CPAP alarm system can be disposed on the apparatus such that the flow of CO.sub.2 from a breathing patient is directed toward the CO.sub.2 concentration sensor when the CPAP air delivery device is in use and is in the proper position for the patient.

Systems and methods herein are directed towards the separation of biologic material to obtain a target cell volume and/or cell concentration for harvesting. The target volume and/or concentration of cells may be obtained through a single cycle via three chambers, or by repeated cycles through one or more chambers to dilute the digestive enzymes used in the process and concentrate the harvestable cell volume to a predetermined target.

In accordance with various embodiments of the disclosed subject matter, an anti-choking apparatus is provided comprising a substantially hollow body comprising a first large cross section body region connected to a second large cross section body region via a small cross section body region; a plurality of auxiliary tubes coupled at respective first ends to respective portions of the body between the first large cross section body region and the small cross section body region, each of the auxiliary tubes having second ends with fans mounted thereat and configured to urge air through the auxiliary tubes and substantially hollow body; and a mouth tube couped at a first end to the small cross section body region and having a second end configured for insertion into an airway of a choking victim; wherein an airflow through the small cross section body region induces a pressure gradient within the mouth tube such that a reduced air pressure at the second end of the mouth tube exerts a force upon an obstruction within the airway.