Embodiments of a syringe-based device for delivering fluid include a housing, a port, the port being positioned at about the distal end of the housing, a plunger assembly, the plunger assembly including, a plunger seal, a valve, and a cannula, a first fluid reservoir, where the first fluid reservoir retains a first type of fluid, a syringe including a syringe body, a syringe port, a plunger, and a second fluid reservoir, the second fluid retaining a second type of fluid, and where the syringe transitions from a first configuration in which a first portion of the first fluid type is delivered through the port, to a second configuration in which the second type of fluid in the second fluid reservoir is delivered through the port, to a third configuration in which a second portion of the first fluid type is delivered through the port.

The present invention relates to a device (10) for supplying a mist of liquid (F). The device (10) is used in combination with a container (20) with an opening (200) for containing the liquid (F). The device (10) includes a main body (100) comprising: (i) a center axis (C); (ii) a liquid chamber (110) formed inside the main body (100), into which a predetermined amount of liquid (F) can be taken up; (iii) a first port (112) formed in a base wall (114) of the main body (100) forming a bottom surface (116) of the liquid chamber (110) so as to face the opening (200) when the device (10) and the container (20) are combined with each other, through which the liquid (F) can flow; (iv) a second port (118) formed in the base wall (114) at a position different from the position where the first port (112) is formed so as to face the opening (200) when the device (10) and the container (20) are combined with each other, through which the liquid (F) can flow; and (v) an aperture (120) connected to the liquid chamber (110), through which a mist of liquid (F) can be released to the outside of the main body (100). The device (10) further includes: a connecting section (122) provided on the main body (100) so as to extend from it in a direction away from the base wall (114) and used for connecting the container (20) to the main body (100); an atomizing element (124) interposed between the liquid chamber (110) and the aperture (120) to atomize the liquid (F) taken up in the liquid chamber (110) and release a mist of the liquid (F) to the outside of the main body (100) from the aperture (120); a first valve (126) mounted on the main body (100) corresponding to the first port (112), wherein the first valve (126) permits the liquid (F) in the container (20) flowing into the liquid chamber (110) through the first port (112) under the influence of gravity, and prevents the liquid (F) in the liquid chamber (110) flowing into the container (20) under the influence of gravity; and a second valve (128) mounted on the main body (100) corresponding to the second port (118), wherein the second valve (128) prevents the liquid (F) in the container (20) from flowing into the liquid chamber (110) through the second port (118) under the influence of gravity, and selectively permits or prevents the liquid (F) in the liquid cha

A system for managing administration of insulin to a user includes an infusion pump to effect controlled delivery of insulin A user interface device displays representations of user intake items. A database stores a catalog of intake items. A programmed processing system is programmed with a baseline user insulin delivery program to make a calculation of insulin to be delivered according to the baseline insulin delivery program or according to a modified baseline insulin delivery program based upon user input data. The user provides user input using the user interface application to identify representations of any of the plurality of intake items and the processing system automatically effects delivery of insulin to the user according to the modified baseline insulin delivery program, instead of the baseline insulin delivery program.

An injector may include a container having a wall with an interior surface defining a closed sterile reservoir filled with a medical fluid or drug product. The injector may also include a fluid delivery system comprising a sterile container needle that is in fluid communication with the container in a delivery state, but may or may not be in fluid communication with the container in a storage state. The sterile container needle is attached to a connector, the connector mechanically coupled to the container to secure the sterile container needle to the container with the needle in the storage state. Further, the injector may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

A delivery device for and method of modulating a condition relating to sodal cognition and/or behaviour in a human subject using oxytocin, non-peptide agonists thereof and/or antagonists thereof, comprising: providing a nosepiece to a first nasal cavity of the subject; and providing a supply unit for administering less than 24 IU of oxytocin, non-peptide agonists thereof and/or antagonists thereof through the nosepiece to an upper region posterior of the nasal valve which is innervated by the trigeminal nerve.

A nose-to-brain drug delivery device is provided. The nose-to-brain drug delivery device includes a freeze-dried drug container for storing a freeze-dried drug, a restoring solvent container for storing a solvent for thawing the freeze-dried drug, a membrane for preventing the freeze-dried drug from being mixed with the solvent, and a compressor for providing a driving force. The membrane is opened by the driving force of the compressor to mix the freeze-dried drug with the solvent, thereby thawing the freeze-dried drug, and the thawed drug is sprayed by the driving force of the compressor.

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a liquid emission mechanism for an inhalation device, as well as a method of emitting a liquid from an inhalation device. The inhalation device comprises a housing (1), a reservoir (2) for storing a liquid, a pumping unit, said unit comprising a riser pipe (5), a hollow cylindrical part (3) having an interior space and being linearly moveable on the riser pipe (5), wherein the pumping chamber is fluidically connected with the reservoir (2), and a nozzle (6) which is connected liquid-tight to an downstream end portion (5B) of the riser pipe (5), and wherein said linear relative motion can be effected by a relative rotation around a rotational axis (R) of a rotatable part (1A) with respect to a counterpart (1B), such that said relative rotation is converted into said linear relative motion by means of a gear mechanism comprising at least one cam surface having a first section (9A) and a second section (9B), and wherein a means for the storage of potential energy (7) is provided. The device is characterized in that said cam surface has, between the first section and the second section (9A, 9B), a third section (9C) of constant height, such that, while said counterpart (1B) slides along said third section (9C), no linear relative motion occurs. A method for the generation of an aerosol comprises, upon rotation of the rotatable part (1B), a first, charging phase for filling the pumping chamber with liquid, and a second, discharging phase for emitting the atomized liquid from the nozzle (6), and is characterized in that between said two phases, a third, resting phase exists during which, despite further rotation, the volume of the pumping chamber remains constant.

Disclosed herein is a method for evaluating Brugada syndrome (BrS) in a subject in need thereof. In some embodiments, the method comprises administering an aerosol of a sodium channel blocker to the subject. Also disclosed herein are compositions, unit doses, and kits for evaluating Brugada syndrome in a subject in need thereof.

The present disclosure relates to an inhalant delivery apparatus to a control system and method for controlling delivery of vapor from the apparatus to a user. The apparatus comprises a vaporization device or box which has an inlet with a seat for receiving an end portion of a separate mouthpiece or combined mouthpiece and wick designed for releasable attachment to the box outlet. The control system controls dispensing of a dose via the vaporizer device and mouthpiece by controlling the timing and amount of medication in the delivered dose, and requires specific input from the user before a dose is dispensed.

A therapeutic device that can diffuse essential oils, infuse frequency into liquids, emit frequency-driven lights, and produce solfeggio tones. The therapeutic device includes an enclosure, at least one oil-diffusing device, at least one frequency-infusing device, at least one frequency-tone generator, a first plurality of ambience lights, at least one vent, and a first controller. The enclosure is used to conceal and protect the electronic components. The at least one oil-diffusing device is used to diffuse fluids. The at least one frequency-infusing device is used to infuse frequency by vibration into fluids. The at least one frequency-tone generator is used to generate tones of different frequencies. The first plurality of ambience lights is used for aesthetic and therapeutic aspects. The at least one vent is used as an escape for the mist produced by the diffusion of the fluids. The first controller is used to manage the electronic components.