An inspiratory resistor valve system (IRV) to regulate intrathoracic pressure during positive pressure breathing, spontaneous inspirations, and CPR may include an inspiratory port. The IRV system may include patient port. The IRV system may include a separate expiratory port. The IRV may include a plurality of atmospheric pressure sensitive valves. The plurality of atmospheric pressure sensitive valves may isolate the expiratory port and the inspiratory port from one another.

An inspiratory resistor valve system (IRV) to regulate intrathoracic pressure during positive pressure breathing, spontaneous inspirations, and CPR may include an inspiratory port. The IRV system may include patient port. The IRV system may include a separate expiratory port. The IRV may include a plurality of atmospheric pressure sensitive valves. The plurality of atmospheric pressure sensitive valves may isolate the expiratory port and the inspiratory port from one another.

A delivery device for and method of delivering a dose of substance for systemic uptake to a nasal cavity of a subject, the delivery device comprising: a nosepiece unit for insertion into a nasal cavity of a subject and comprising an outlet unit which includes at least one nozzle for delivering substance for systemic uptake substantially only to surfaces in one or both of the anterior region and an anterior section of the posterior region of the nasal cavity of the subject; and a substance supply unit which is operable to deliver a dose of substance to the at least one nozzle.

A syringe-based device includes a housing, the housing including a port, and an actuator mechanism including a first member and a second member configured to be movably disposed within the housing. The first member includes a syringe body and a plunger movably disposed within the syringe body and including a first plunger seal. The second member includes a second plunger seal defining a channel and a valve fluidically coupled with the channel of the second plunger seal. The device also includes a first fluid reservoir and a second fluid reservoir. The device transitions from a first configuration to a second configuration in which a first type of fluid in the first fluid reservoir is delivered through a port, to a third configuration in which a second type of fluid within the second fluid reservoir is delivered through the port.

There is provided an aerosolizable gel comprising (a) an active agent; (b) one or more gel forming materials, wherein the one or more gel forming material is at least one phyllosilicate; (c) an aerosol forming material selected from glycerol, propylene glycol and mixtures thereof; and (d) water.

The invention relates to an inhaler, particularly an electronic cigarette product, comprising at least one evaporator device having at least one electrical evaporator for evaporating liquid supplied to the evaporator and an electronic control device for controlling and/or regulating the evaporator. A plurality of liquids are associated or can be associated with the evaporator device in such a way that the composition and/or the vapour production rate of the vapour/aerosol produced by the at least one evaporator can be adjusted and/or modified in a targeted manner, as the control device is designed for individual control of the at least one or each individual evaporator and/or for group control of the evaporators.

In some embodiments, an ophthalmic cassette valve may be configured to control flow of an infusion fluid and an ophthalmic substance (e.g., ophthalmic drug, a retina patch material, or an ophthalmic dye) to an infusion cannula. The valve may be configured to provide an alternating or mixed flow of the infusion fluid and the ophthalmic substance to the infusion cannula. In some embodiments, the cassette may include multiple substance chambers with different substances. The cassette may also include a one or more valves to control the flow to the infusion fluid (e.g., on/off for each of the substances and infusion fluid and/or a ratio of the substances and infusion fluid).

An inspiratory resistor valve system (IRV) to regulate intrathoracic pressure during positive pressure breathing, spontaneous inspirations, and CPR may include an inspiratory port. The IRV system may include patient port. The IRV system may include a separate expiratory port. The IRV may include a plurality of atmospheric pressure sensitive valves. The plurality of atmospheric pressure sensitive valves may isolate the expiratory port and the inspiratory port from one another.

An inspiratory resistor valve system (IRV) to regulate intrathoracic pressure during positive pressure breathing, spontaneous inspirations, and CPR may include an inspiratory port. The IRV system may include patient port. The IRV system may include a separate expiratory port. The IRV may include a plurality of atmospheric pressure sensitive valves. The plurality of atmospheric pressure sensitive valves may isolate the expiratory port and the inspiratory port from one another.

An anion fall generating device and method, which comprises a water mist generator, an anion generator and an airflow propulsion unit. The water mist particles generated by the water mist generator and the anions generated by the anion generator are fused with each other under the effect of airflow propulsion unit, forming a water mist anion fall. The water mist particles are used as carriers, the water mist particles and anions are fused with each other, so that the water mist particles enwrap or adhere to the anions, preventing the anions from being neutralized by positive charges, so as to form the anion fall using water mist particles as carriers. Meanwhile the water mist particles can prolong the lifespan of anions in the air, and the anions are propagated farther by airflow propulsion unit, the anion generating efficiency is increased greatly.