A system for delivery of aerosol therapy includes a housing defining a chamber. The housing has a base, a top and a main body extending therebetween. An ambient air inlet is adjacent the base and is normally closed by an inlet valve. The housing has a patient port. Exhaled air is exhausted through valves in a mouthpiece or a face mask to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.

A syringe-based apparatus includes a housing having an open proximal end and a distal end, a needle coupled with the distal end of the housing, an actuator mechanism coupled with the housing, the actuator mechanism including a syringe body and a plunger, the syringe body and the plunger being insertable into the open proximal end of the housing. A medicament reservoir is defined at least partially by the housing and the actuator mechanism, and a reconstitution fluid reservoir is defined at least partially by the syringe body and the plunger of the actuator mechanism. The plunger is operably configured to move relative to the syringe body to expel the amount of the fluid from the reconstitution fluid reservoir into the medicament reservoir. The actuator mechanism is operably configured to move relative to the housing to expel the amount of the fluid from the medicament reservoir through the needle.

A nebuliser device with a vibrating mesh, for administering medicaments is provided. The nebuliser device includes a casing, a nozzle, a nebuliser and a chamber that houses a medicament. The chamber housing a medicament is a disposable capsule forming an independent body that can be extracted from the casing of the device. The disposable capsule attaches to the nebuliser and to the casing. An attachment between the nebuliser and the casing allows the disposable capsule to be coupled to the nebuliser device or to be uncoupled therefrom.

Diffusion and infusion resistant implantable devices and methods for reducing pulsatile pressure are provided. The implantable device includes a balloon implantable within a blood vessel of a patient, e.g., the pulmonary artery. The balloon is injected with a fluid mixture comprising a constituent fluid(s) and a diffusion-resistant gas to provide optimal balloon volume and limit fluid diffusion throughout multiple cardiac cycles. The fluid mixture may be pressurized such that the balloon is transitionable between an expanded state and a collapsed state responsive to pressure fluctuations in the blood vessel.

An injector may include a container having a wall with an interior surface defining a closed sterile reservoir filled with a medical fluid or drug product. The injector may also include a fluid delivery system comprising a sterile container needle that is in fluid communication with the container in a delivery state, but may or may not be in fluid communication with the container in a storage state. The sterile container needle is attached to a connector, the connector mechanically coupled to the container to secure the sterile container needle to the container with the needle in the storage state. Further, the injector may include an actuator that is adapted to move the container needle from the storage state to the delivery state.

The invention relates to a valve, in particular for a device for administering a liquid medicament, with a valve body which has an interior for receiving a liquid, wherein the valve body has a liquid inlet and an opposite liquid outlet which both open into the interior, wherein the interior accommodates a large number of micro channels which extend in a connection direction between the liquid inlet and the liquid outlet. A corresponding device for administering a liquid medicament is also described.

A method for the treatment of paranasal sinus disease, administering a treatment formulation or a drug treatment formulation through the nasal cavity directly into a paranasal sinus.

A modular electronic inhaler having an embedded system and a method for precise and repeatable delivery of multiple types of medications in different forms to the pulmonary system of a human user. The inhaler can include a first MDI housing defining an internal chamber for accommodating a MDI medication cartridge and a second DPI housing defining an internal chamber for accommodating a DPI medication cartridge. Meter reservoir compartments in each housing can automatically provide precise doses of medicine using vacuum pressure sensors. The sensors can be in communication with the internal embedded system/electronics (microcontroller) of the inhaler and the electronics/microcontroller can be in permanent communication with a software application running on the user's smart phone or other electronic device.

A device for delivering a predetermined volume a substance within a body cavity. The device includes: at least one predefined volume sized and shaped to contain a predetermined volume the substance; a delivery end in fluid communication with a container; and at least one valve mechanically connected to the container and configurable between an active configuration in which the valve enables delivery of a volume of the substance and an inactive configuration, in which the valve prevents delivery.

A transfer device for living organisms is used for placing an object in a living organism. The transfer device for living organisms includes a tubular needle extending in one direction, and a pushing member located inside the needle. The needle is configured to capture an object therein from an opening at a tip of the needle. The pushing member is configured to be movable relative to the needle from inside the needle toward the opening.