A cartridge for a dispensing device, such as a nebulizer, for dispensing a medicament composed of or produced from a plurality of components and a system including a dispensing device, such as a nebulizer, and such a cartridge. The cartridge includes at least two fluidically separated chambers which each contain at least one component of the medicament, an actuating mechanism for fluidically connecting the chambers and mixing the components for the dispensing of the medicament A method for preparing a medicament composed of a plurality of components in a cartridge for the dispensing of said medicament by way of a dispensing device, such as a nebulizer, where a plurality of fluidically separated chambers of the cartridge are fluidically connected, and a component of the medicament is at least partially transferred from one of the chambers to another of the chambers with another component of the medicament in order to mix the components. Only once the components have been mixed is the cartridge opened for the extraction of a dose of the medicament.

Embodiments include devices and methods configured to fractionally resect skin and/or fat. Fractional resection is applied as a stand-alone procedure in anatomical areas that are off-limits to conventional plastic surgery due to the poor tradeoff between the visibility of the incisional scar and amount of enhancement obtained. Fractional resection is also applied as an adjunct to established plastic surgery procedures such as liposuction, and is employed to significantly reduce the length of incisions required for a particular application. The shortening of incisions has application in both the aesthetic and reconstructive realms of plastic surgery.

A closed system for harvesting fat through liposuction, concentrating the aspirate so obtained, and then re-injecting the concentrated fat into a patient comprises as its main components a low pressure cannula having between about 7 to 12 side holes of about 1-2 mm by 2.0 to 4.0 mm, a spring loaded syringe holder with a constant force or coiled ribbon spring to apply a substantially constant pressure over the full excursion of the plunger, and a preferably flexible collection bag which is also preferably graduated, cylindrical over most of its body and funnel shaped at its bottom, all of which are connected through flexible tubings to a multi-port valve. The multi-port valve has two flutter/duck bill valves which restrict the fluid flow to a one way direction which effectively allows the syringe to be used to pump fat out of a patient and into a collection bag in a continuous manner. After the bags are centrifuged to concentrate the fat, the excess fluids are separated and the valve is re-connected to permit the syringe pump to reverse fluid flow to graft the concentrated fat back into the patient.

Provided is a device for suctioning bodily fluids and for supplying a fluid substance to a human or animal body, in which the device includes a drive unit (1, 1′, 1″; 2) having a drive (20), a pump head (30, 30′, 30″) which is drivable by the drive (20) and a connecting part (5, 7′, 4″) which is releasably connectable to the drive unit (1, 1′, 1″; 2) and has a tube guide (555, 710′, 43″). The tube guide (555, 710′, 43″) is realized in such a manner for receiving a tube (I) that the tube, in combination with the pump head (30, 30′, 30″), forms a peristaltic pump (3) by way of which the fluid substance is conveyable through the tube (I) to the human or animal body. The pump head (30, 30′, 30″) is incorporated in the connecting part (5, 7′, 4″), and the drive unit (1, 1′, 1″; 2) includes a coupling element (24, 24′) which is connected to the drive (20) in order to couple the pump head (30, 30′. 30″) to the drive (20).

Systems, devices, and methods of the present disclosure assist with management of tubes and hoses during surgical procedures. The systems, devices, and methods provide for the proper opening and closing of tubes to facilitate performance of steps in a surgical procedure. Systems, devices, and methods of the present disclosure control fluid delivery to and from a medical device, including devices for tissue processing and cleaning.

A breast shaping method using a barbed suture and a suture handling device. The breast shaping method includes inserting a tensioning barbed suture in medialmost and lateralmost portion of the inframammary fold from deep soft tissues (muscle/pericondrium-periostium to and along the subdermal layer of the inframammary fold, with an end portion of the barbed suture being left outside of the skin, thereby allowing the barbed suture to be tensioned, tensioning the end portion of the barbed suture arranged by the insertion of the barbed suture, so that the barbed suture pulls tissues of the subdermal layer, thereby lifting the inframammary fold and defining a nice indentation of the inframammary fold, and cutting the end portion of the barbed suture outside of the skin after the tensioning of the barbed suture.

The present invention is related to the field of tissue regeneration. It concerns more particularly new standardizations and medical devices for the preparation of A-PRP, PRP, BMC, fat tissue, alone or in combination with a biomaterial or cell extract.

The present invention features methods of manipulating subdermal fat in a treatment area. Such methods include inserting a needle (e.g., a micro-coring needle) through the dermis to the subdermal fat layer in order to excise a portion of tissue from the treatment area. These insertions result in a portion of the dermis and a portion of subdermal fat to enter into the needle. Removal of the needle results in excision of the portion of dermis and subdermal fat that entered into the needle.

A morselizer comprising (a) a hollow cylindrical structure with an inner wall and an outer wall and comprising a first end section, a second end section, and a center section extending axially between the first end section and the second end section providing a substantially axial liquid pathway therein; (b) wherein each end section comprises a axially and radially hollow luer fitting that is attachable to a structure with a complementarily sized luer fitting; and (c) one or more blades extending transversally across the inner diameter of the center section wherein (i) each blade is comprised of a plurality of ends, including a posterior end secured to at least the center wall section inner wall at a center section inner wall first position and an anterior end proximal a center section inner wall second position opposite the center section inner wall first position, with a gap positioned between the blade anterior end and the center section inner wall second position, and (ii) at least two ends comprise cutting ends.

Methods of treating a medical condition in a patient include performing a lipectomy of visceral fat to remove a quantity of the visceral fat from the subject. The removal of visceral fat treats the medical condition such that the subject experiences at least a reduction of symptoms of the medical condition.