A fat sizing device includes a first filter element and a second filter element. The first filter element has an exterior formed from a ceramic such as titanium nitride. The second filter element is positioned in series with the first filter element and has an exterior formed from an organic polymer such as a parylene. The first filter element has a first mesh size and the second filter element has a second mesh size different than the first mesh size and may be less than the first mesh size.

A problem with injecting cells such as fat cells into organic tissue to act as a filler material is that the cells must be distributed evenly and reasonably thinly to ensure that all of the injected cells are situated near to a blood supply and do not die. Injecting devices have been produced that use electronic controls and electro-mechanical mechanisms to improve distribution. The present approach however solves the problem of even distribution by coupling a skin surface sensing means to a plunger in a reservoir of the filler cells. In this way, the flow of cells out of a cannula relates directly to the rate at which the tip of the cannula penetrates the organic tissue into which the cells are being injected.

A method for autologous soft tissue transfer and a single use surgical kit are provided. The method includes harvesting soft tissue with a tumescent fluid and filtering the harvested soft tissue to obtain a drained aspirate. The single use surgical kit includes at least one syringe, at least one infiltration cannula, at least one aspiration cannula, and at least one tissue filter. The infiltration cannula has a spiral hole array.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, fractional scar revision, and/or fractional tattoo removal. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

Devices and methods for tissue transfer are described where a cannula may be inserted into the breast of a subject at one of several points of entry. Insertion of the cannula into the breast may be accomplished by using a guidance system to distinguish between tissue types. Once desirably positioned, the cannula may be withdrawn from the breast while automatically (or manually) injecting the fat in multiple deposits of adipose tissue or fat such that the deposited fat remains within the tract formed by the withdrawn cannula. Multiple tracts of the deposited fat may be injected within the breast until the breast has been desirably remodeled and/or augmented.

A portable apparatus for collection and processing of human biological material containing adipose, such as extracted during a lipoplasty procedure, is useful for multi-step processing to prepare a concentrated product (e.g., stromal vascular fraction) or a fat graft composition. The apparatus has a container with an internal containment volume including an available processing volume in a range of from 75 cubic centimeters to 1300 cubic centimeters, and with a tissue retention volume and a filtrate volume separated by a filter and with a tapered portion to a collection volume for collecting concentrate product. The apparatus has a mixing device for mixing contents within the tissue retention volume, and including a rotatable shaft extending from outside of the internal containment volume to inside of the internal containment volume and comprises at least one mixing member that is disposed in the tissue retention volume and is connected with the shaft to move through the tissue retention volume relative to the filter when the shaft is rotated. Methods include use of the apparatus to process human biological material containing adipose, such as to prepare a stromal vascular fraction concentrate product or a fat graft composition.

A cannula having a coupling force and fixing force between an expansion part and a needle is provided. The needle is formed in a cylinder shape having a predetermined length, and includes a coupling means, which is formed at the outer surface thereof, and is inserted into the expansion part such that the coupling force can increase by the friction with the expansion part during adhesion, wherein the coupling means includes: a groove part formed, in an insertion region of the needle inserted into the expansion part, by the melting of the outer surface of the needle through laser machining so as to have a predetermined depth; and a protrusion part protruding in the outward direction of the needle so as to be connected to the groove part.

The present invention relates to a fat suction and graft syringe, and more specifically, to a fat suction and graft syringe having a negative pressure adjustment means, wherein a negative pressure state in a barrel can be maintained during a procedure only by pulling and releasing a plunger, and only by slightly rotating the plunger, the plunger can be pushed inside the barrel without being constrained by a multi-level holding plate and a single-surface rotation clip, whereby the syringe has enhanced convenience in the use and production thereof so that many practitioners accustomed to using a normal syringe can easily use the syringe without separately learning how to manipulate the syringe.

A tissue separating device (100) is provided. The tissue separating device (100) includes a canister device (20) including a canister body (21) defining a volume. A tissue retrieval port (36) can be arranged on the canister device (20) and is capable of being arranged in fluid communication with a harvesting device (300) for directing a fatty liposuction aspirate into the volume of the canister device (20). An adjustable height filtration mesh assembly (50) can be arranged within the canister body (21) and can include a filtering mesh (62). A tissue harvesting port (24) can be arranged in the sidewall of the canister body (21) and can be capable of being arranged in communication with a collection device (400) to allow the tissue harvesting port (24) to atraumatically receive a filtered pure fat collected on the filtering mesh (62). The filtration mesh assembly (50) can be movably arranged within the canister body (21) such that the filtering mesh (62) is adjustable with respect to the tissue harvesting port (24).

The dual syringe with percutaneous cannula is a medical device for harvesting and transferring cells for autologous transplantation without the requirement of a surgical setting or ambulatory care. The dual syringe is a closed sterile system that allows for the harvesting syringe to harvest the cells/tissue from a first location of a patient which is then centrifuged to aggregate the cells. The aggregated cell pellet is transferred to a transfer syringe. The cell pellet is then reinjected by the transfer syringe into the patient at a second location for therapeutic purpose. The percutaneous cannula permits insertion of a cannula, with the assistance of a needle, without the need of a surgical incision or trocar.