A skin treatment device used for cellulite treatment, skin tightening or body contouring which combines negative pressure treatment and RF treatment, where the RF treatment uses variable frequencies during a treatment cycle.

An external medical device includes a fluid inlet, an inlet valve in fluid communication with the fluid inlet to control fluid flow through the fluid inlet in response to fluid inlet control signals, a fluid outlet in fluid communication with a fluid reservoir, a fluid pump configured to deliver a therapeutic fluid from the fluid reservoir through the fluid outlet in response to fluid outlet control signals, a fluid sensor configured to monitor the therapeutic fluid between the fluid pump and the fluid outlet and further configured to output sensor data corresponding to a monitored condition of the therapeutic fluid, and a control module configured to receive the sensor data and output, based on the sensor data, the fluid inlet control signals to the inlet valve and the fluid outlet control signals to the fluid pump.

Systems, instruments, and methods for minimally invasive procedures including one or more of fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision are described. Embodiments include instrumentation comprising a scalpet assembly coupled to a carrier, and the scalpet assembly includes a scalpet array. The scalpet array includes one or more scalpets configured for fractional resection, fractional lipectomy, fractional skin grafting, and/or fractional scar revision. The system includes a vacuum component coupled to the scalpet assembly and configured to evacuate tissue from the a site. The carrier is configured to control application of a rotational force and/or a vacuum force to the scalpet assembly.

An injector arrangement which allows the fat tissue to be drawn through a suction tip, stored inside a tube without intervention or exposure to air and centrifuged obtain fat based stem cells. The arrangement includes a modular piston with a movable structure which allows drawing the fat tissue into the tube through the suction tip by a piston tip seal, a piston shaft with modular structure which allows the said modular piston to move inside the tube and which can be separated from the modular piston in order to allow the tube to be placed inside the present centrifuge device after the fat tissue is drawn inside the tube, and an O-ring which engages into the O-ring seat formed on the hollow locking part in order to make the hollow locking part introduced on the modular piston to act as a locking device during the centrifuge.

A fat-harvesting syringe having a multi-functional plunger assembly. The plunger assembly comprises an outer plunger rod body, an inner central plunger rod and a piston seal assembly. The outer plunger rod body having a first and a second end. The first end having a central lumen all at its finger grip handle and at the second end having flanges that are expandable. Once the central plunger inner rod is inserted fully into central lumen of plunger rod body, the expandable flanges expands and engages with the piston seal assembly. Also when the inner plunger rod is retracted, the plunger body flanges retract back and disengages from piston seal assembly.

The present disclosure provides systems and methods for transfer of tissue or other materials such as adipose tissue. The systems and methods can include a vessel and a syringe to facilitate transfer of tissue between one or more vessels and tissue implantation devices.

This disclosure provides a guiding device shaped so as to hold a syringe equipped with a harvesting cannula and to allow to insert the harvesting cannula at the exact depth below the skin of the patient to attain the subcutaneous adipose tissue. The cannula may be moved move back and forth in a driven manner immersed in the subcutaneous adipose tissue without any risk of wounding inner organs of the patient and in the proper layer. This disclosure provides also a syringe holder in the form of a hollow box with circular openings on a top surface. The circular openings are shaped so as to let a barrel of a syringe enter therein and a barrel flange not pass therethrough, in order to keep harvesting syringes hung with their barrel flanges abutted against the top surface of the syringe holder and their barrels protected into the hollow box.

A vibrating hand held surgical instrument for loosening tissue of a patient for liposuction or body contouring procedures. The instrument includes a motor connected to a vibration actuator having an eccentric rotating mass and an end effector for engaging tissue operatively connected to the vibration actuator, wherein the motor rotates the eccentric mass to cause the end effector to vibrate to loosen tissue. A flexible shaft having first end and second ends dampen the vibration to the motor and to the operator handle.

The invention relates to a device for separation of fluidal biological material components, particularly separation of components of the material collected by liposuction for subsequent transfer of the adipose tissue in an injection form. The device comprises a container with an outlet duct arranged in it, the outlet duct having its upper end adapted for collecting the material, and its lower end that is in fluid communication with the inner space of the container at its bottom. Further, the invention relates to a separating float for separation of the fluidal biological material components, the float being intended to be used in the device, wherein the float comprises at least one by-pass opening for passage of the fluidal biological material contained in the container from the area below the separating float into the area above it. The invention also relates to a kit including the device and the float.

Provided are a treatment method, a separation method, and a filter assembly capable of preventing so-called Blue Toe syndrome which is so-called cholesterol crystal embolism of which a fat-soluble compound such as cholesterol crystals generated during dilation of a stenosed site causes clogging in glomeruli of peripheral capillaries or kidney, acute renal failure, and the like. Cholesterol crystals generated from plaque during use of a balloon catheter are taken out of the body and removed using a centrifugal separation device or a filter, and usable living cells are returned to the body to reduce blood transfusion and reduce cholesterol crystal embolism.