Systems, devices and methods for use in liposuction and infusion medical procedures including handheld devices, micro-cannulas, curved cannulas vacuum pressure changing features.

The present disclosure is directed to devices, systems, and methods for sensing and discerning whether a distal portion of a fat grafting cannula or probe is disposed in fat tissue or muscle tissue during fat grafting procedures. In one aspect of the present disclosure, a fat grafting cannula or probe is provided including first and second electrodes. Each electrode is coupled to a circuit, e.g., disposed in an electrosurgical generator. During a fat grafting procedure, the electrodes contact patient tissue. Based on signals received from each electrode, the circuit is configured to determine whether a distal portion of the fat grafting cannula is disposed in a fat tissue or muscle tissue. If the circuit determines that the fat grafting cannula is disposed in muscle tissue, the surgeon operating the fat grafting cannula is alerted to ensure that processed fat is not injected into the muscle tissue of the patient.

The present invention relates to a device and a method for FIG. 2 treating fat cells taken from a patient and intended for a transplant. More specifically, it relates to a device and a method by suctioning which makes it possible to separate the viable fat cells from the residues and elements which are not transplantable. The device is a device for treating adipose tissues (G) connected to a suctioning means (M), consisting of a sealed treatment chamber (A) comprising a means for connection (17) to said suctioning means (M), a means for inlet (13) of said adipose tissues before treatment, a filtration means (3) and at least one means for outlet (20) of said adipose tissues (G) after treatment, said filtration means (3) comprising a conically shaped external wall (3 1, 3) comprising a narrow base (55) attached to an impeller (25) and an internal sieving means (30) connected to the output means (20), said impeller (25) being subjected to the air pressure reduction created by the suctioning means (M) and constituting a rotary mechanical actuating means for actuating said filtration means (3).

Systems and methods for cleansing blood are disclosed herein. The methods include acoustically separating target particles from elements of whole blood. The whole blood and capture particles are flowed through a microfluidic separation channel formed in a thermoplastic. At least one bulk acoustic transducer is attached to the microfluidic separation channel. A standing acoustic wave, imparted on the channel and its contents by the bulk acoustic transducer, drives the formed elements of the blood and target particles to specific aggregation axes.

A minimally invasive cosmetic procedure for de-bulking fat includes steps of: (a) injecting platelet rich plasma (PRP) into a subject area; followed by (b) heating fat cells in the subject area using radiofrequency; followed by (c) aspirating fat cells in the subject area using liposuction; followed by (d) injecting platelet rich plasma (PRP) into the subject area again. The PRP injecting step (a) may be performed two to seven weeks prior to the heating and liposuction steps (b) and (c); and the PRP injecting step (d) may be performed several days to four weeks after the heating and liposuction steps (b) and (c).

Non-enzymatic method and milling device for preparing therapeutic cells from adipose tissue comprising: continuously feeding the adipose tissue to the milling device (2); mechanically separating the cells or cell aggregates from adipose tissue moving through the milling device (2) by means of a multiplicity of blades (19) of a rotor (10), wherein the blades (19) are arranged in a spaced arrangement with respect to the overall direction of flow and the blades (19) are moving about an axis of rotation (18), wherein the axis of rotation (18) is provided essentially parallel to said overall direction of flow; continuously withdrawing the processed tissue comprising the separated cells from the milling device (2).

Exemplary embodiments of method and apparatus are provided for damaging and/or removing portions of subcutaneous fatty tissue while leaving the overlying dermal layer of the skin substantially undamaged. One or more hollow needles can be provided that include an arrangement within the lumen configured to retain or damage portions of fatty tissue that enter the lumen. Properties of the needle can be selected such that the needle can be inserted into skin and pass through the dermal layer, allowing fatty tissue to enter the distal portion of the lumen as it is advanced further, and then leaving the dermis undamaged when withdrawn. Such exemplary apparatus can include a plurality of such needles, a reciprocating arrangement to mechanically advance and withdraw the one or more needles, and/or a vibrating arrangement.

A system and method are provided for minimally-invasive selective fat removal from a target area by injecting the area with a solution of photo-absorbing nanoparticles and irradiating the injected area with a beam of near infrared (NIR) light. The NIR emission wavelength excites the nanoparticles to melt fat within the target area so that the liquefied fat can be aspirated from the target area. The nanoparticles may be gold nanorods having aspect ratios selected to produce surface plasmon resonance when irradiated with NIR light around 800 nm.

Harvested adipose tissue is processed in a single-use portable processing container to prepare a centrifuges pellet phase of stromal vascular fraction concentrate, which is selectively removed and disposed in a syringe dispersed in a dispersion medium to prepare an osteoarthritis treatment product.

Disclosed are methods and devices for processing lipoaspirate that include mechanically-processing harvested lipoaspirate in a liposuction filter canister. In some embodiments, the devices are liposuction devices that include a lipoaspirate processing unit for mechanically-processing lipoaspirate. The mechanical processing reduces the average size of adipose tissue pieces in the lipoaspirate without substantially rupturing lipocytes therein.