Simulated anatomical components, such as simulated vascular vessels, produced by a method that includes forming an anatomical component mold from a soluble polymer such that the mold defines an interior void of the simulated anatomical component. One or more layers of an elastomeric material is applied around the anatomical component mold and the material is allowed to cure to form a wall of the simulated anatomical component. At least a portion of the mold is dissolved to form a passage for liquid within the simulated anatomical component. Simulated anatomical components are connectable to other components of a surgical simulation system and can be modularized.

Disclosed herein are kits for use in adding degradable foam to a tire, methods for preparing a degradable foam-containing tire, tires containing degradable foam, and methods for degrading the degradable foam in tires containing degradable foam. The degradable foam comprises a combination of (i) at least one di- or polyisocyanate, (ii) at least one polysiloxane diol, at least one polysiloxane diamine, or a combination thereof, and (iii) optionally at least one polyol.

Tools for sealing a tubing in a downhole environment. The tools feature top and bottom slip assemblies and a monolithic sealing element. The monolithic sealing element includes a portion that is disposed between the top and bottom slip assemblies as well as portions that encapsulate the slip assemblies. When the tool is actuated from a run-in configuration to a set configuration, the slips move toward each other squeezing the sealing element so that it forms a fluid-tight seal with the tubing. Teeth of the slip assemblies penetrate the portions of the sealing element disposed thereon and bite into the tubing.

Disclosed herein are methods of making and using compositions comprising medical devices, particularly medical devices made from resorbable polymers.

A fiber-reinforced plastic substrate is described in which a plurality of resins having different properties are firmly compounded and that includes components [A], [B], and [C]: [A] reinforcing fibers; [B] thermoplastic resin (b); and [C] thermoplastic resin (c),
wherein the component [A] is arranged in one direction, in the fiber-reinforced plastic substrate, a resin area including the component [B] and a resin area including the component [C] are present, the resin area including the component [B] is present on a surface of one side of the fiber-reinforced plastic substrate, and a distance Ra.sub.(bc) between Hansen solubility parameters of the component [B] and the component [C] satisfies formula (1):

Ra.sub.(bc)={4(δDB−δDC).sup.2+(δPB−δPC).sup.2+(δHB−δHC).sup.2}.sup.1/2≥8

wherein Ra.sub.(bc), δDB, δDC, δPB, δPC, δHB and δHC are as defined.

A coated tubular construct for biological and industrial applications includes a plurality of channels, where each channel is radially surrounded by a wall comprising a first polymer, and a conformal coating comprising a second polymer is disposed on an outer and/or an inner surface of each wall. A method of producing a tubular construct includes 3D printing a template structure comprising a sacrificial material and a photoinitiator, and immersing the template structure in a first prepolymer solution comprising a first prepolymer and a co-initiator. During the immersion, the template structure is exposed to light, and the first prepolymer undergoes radical polymerization to conformally coat the template structure with the first polymer, forming a coated template. The sacrificial material is removed from the coated template, and a tubular construct comprising the first polymer is formed.

Compositions and methods for making biodegradable plastic products are provided. The compositions include a destabilizing agent that makes the finished plastic biodegradable. The compositions also can include an oil-based carrier, such as cottonseed oil, that allows the biodegrading agent to be metered into a continuous plastic manufacturing process. The compositions further can include an additive that allows the biodegrading additive to combine with the carrier; an optical brightener to improve the appearance of the finished plastic product, and to indicate the presence of the composition in the finished product; and a pigment, so that the composition can act as a liquid coloring agent.

A method of manufacturing a fluid control device includes extruding a polymer melt into a chamber defined by an outer surface of a support structure and a disintegrable metallic tubular member disposed at the support structure, the polymer melt comprising a high heat polymer and a foaming agent, the high heat polymer having a heat deflection temperature of about 100° C. to about 300° C. measured at 1.82 MPa in accordance with ASTM D648-18; sealing the chamber; and foaming the high heat polymer to produce a porous filtration medium in a compacted shape.

Compositions and methods of preparing amorphous drug formulations through hot melt extrusion which result in decreased decomposition of the desired drug are provided herein. Also provided are methods and compositions which further comprise a pharmaceutically acceptable thermoplastic polymer. In some embodiments, these compositions comprise a therapeutically active agent which is only sparingly soluble in water.

Simulated anatomical components, such as simulated vascular vessels, produced by a method that includes forming an anatomical component mold from a soluble polymer such that the mold defines an interior void of the simulated anatomical component. One or more layers of an elastomeric material is applied around the anatomical component mold and the material is allowed to cure to form a wall of the simulated anatomical component. At least a portion of the mold is dissolved to form a passage for liquid within the simulated anatomical component. Simulated anatomical components are connectable to other components of a surgical simulation system and can be modularized.