A CPR training device is disclosed comprising a first member including a mouthpiece portion and a first engaging portion, a second member including an output portion and a second engaging portion, and an air passageway. The first engaging portion and the second engaging portion cooperates to form a filter seating arrangement at a filter seat position when assembled together to secure a filter within the CPR training device. The air passageway is open to air outside of the CPR training device only through the mouthpiece portion and the output portion. The filter is disposed in the air passageway at the filter seat position.

Embodiments of the present disclosure provide systems and devices for delivering gaseous Nitric Oxide (gNO) under therapeutic parameters to reduce infection in a subject. Certain embodiments include devices and systems for delivering pressurized gNO to reduce bioburden and promote healing in the wounds of subjects having various disease conditions, including skin and soft tissue infections (SSTIs) and osteomyelitis. In some embodiments, the present disclosure provides portable wound healing devices for delivering pressurized gNO to the site of a wound to treat various disease conditions in a subject. Other embodiments relate to systems and devices for delivering and for monitoring gaseous Nitric Oxide (gNO) under therapeutic parameters of use to treat a subject. In certain embodiment, the devices include a subject interface unit comprising sensors for detecting gNO pressure and/or gNO flow.

A nebuliser cup for maintaining a safe level of liquid during nebulization, the cup comprising a liquid level sensor comprising: a first element sensing liquid at or below a position corresponding to a filled liquid level in the nebuliser cup; a second element electrically isolated from the first element and located at a position corresponding to a filled liquid level in the nebuliser cup; and wherein when the cup is not filled with a liquid to the filled liquid level, the first element, the liquid and the second element do not form an electrically coupled circuit; and when the cup is filled with a liquid to the filled to liquid level, the first element, the liquid and the second element together form an electrically coupled circuit.

The disclosure provides methods of making a cell-containing product having a uniform amount of cells therein. The method comprises pooling red blood cells from a plurality of blood units, and inactivating any pathogen contained therein. A storage solution added to the cellular component results in a cell-containing product that is essentially pathogen and white blood cell free and has an extended shelf life of about 42 to about 100 days. The cell-containing product is further divided into units which comprise a uniform dose of RBCs per unit.

Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

A device for killing blood-borne pathogens, and a method of using this device to effectively remove blood-borne pathogens from the body of a human or animal is claimed. The device comprises a wire that is inserted into the blood stream of a patient, which releases metallic ions which effectively kill the pathogens. There are several embodiments, each of which has a combination of covered and uncovered portions of the wire. The wire is electrically connected to both a source of power and a Power Supply with PCB or controller/software, which controls the intensity and during of the treatment.

Embodiments are described for treating a fluid, e.g., a biological fluid. The embodiments may include systems, apparatuses, and methods. Embodiments may provide for a flow cell, with a plurality of manipulation elements, through which a fluid is flowed. The fluid may be treated (e.g., exposed to energy) as it moves through the flow cell. In embodiments, the flow cell may be used to inactivate pathogens in the fluid.

The disclosure provides methods of making a red blood cell, plasma, and platelet products having a uniform dose and volume. The method comprises pooling a plurality of blood units, leukoreducing the blood and inactivating any pathogen contained therein. Plasma, RBCs, and platelets are then divided into uniform dose and volume units which have an extended shelf life.

An intubation assembly and shield configured to at least partially reduce the risk of contagion of airborne illnesses. The intubation assembly comprises an intubation apparatus assembly, which may comprise an intubation apparatus such as a laryngoscope, endoscope, bronchoscope, or other fiberoptic device. The intubation apparatus assembly may be operatively disposed on the shield assembly. The intubation apparatus may be placed on a correspondingly dimensioned sleeve. The shield assembly comprises a body with a plurality of side segments and a first transparent component with a shield opening disposed thereon. The shield opening may be used for insertion of the intubation apparatus assembly. The shield assembly may also comprise a second transparent component with at least one longitudinally disposed slot for insertion of an endotracheal tube or other intubation apparatus(es). The shield assembly may be provided with ports to attach a vacuum device to provide negative pressure.