A wearable drug delivery device has a needle assembly and a drug vial arranged side-by-side. This arrangement makes the device compact so that it can be easily worn around a user's wrist, for example. When the user triggers the device to inject a dose of medication like epinephrine, in an orchestrated sequence, a first spring drives the needle assembly downward and inserts a needle into the user while connecting the needle assembly to the drug vial. A second spring then delivers the dose from the drug vial through the needle and into the user. Advantageously, the small form factor encourages the user to wear the device and have lifesaving medication at the ready.

A first member (10) and a second member (20) are coupled to each other in a coupling portion (100). The first member includes, on the opposite side to the coupling portion, a main portion (51) that is connectable to a counterpart connector. The main portion and the second member are in communication with each other via a flow channel (102). One of the first member and the second member includes an outer cylindrical portion (30), and the other of the first member and the second member includes an inner cylindrical portion (40). In the coupling portion, the inner cylindrical portion is fitted in the outer cylindrical portion. The outer cylindrical portion includes a first engagement portion (31) and an abutment portion (35). The inner cylindrical portion includes a second engagement portion (41) that engages the first engagement portion, and a leading end (45) that is a front end of the inner cylindrical portion in a direction in which the inner cylindrical portion is fitted into the outer cylindrical portion. As a result of the first engagement portion and the second engagement portion engaging each other, the leading end of the inner cylindrical portion abuts against the abutment portion of the outer cylindrical portion along a central axis (101).

A chest valve including: a housing including an inlet configured to connect to a chest tube, an outlet and a fluid passage from the inlet to the outlet; and a one-way valve within the housing and included in the flow passage, wherein the one-way valve includes: (i) a first tubular strip wherein having an internal air passage and a first layer defining the air passage, wherein the first layer has a first thickness and the internal air passage of the first tubular strip is included in fluid passage of the housing; and (ii) a second tubular strip wherein having a second layer with a second thickness with a second thickness greater than the first thickness, wherein an outer surface of the second tubular strip is adjacent and overlaps an outer surface of the first tubular strip.

In some examples, a catheter includes an elongated body that includes an inner liner, and outer jacket, and a structural support member positioned between at least a portion of the inner liner and the outer jacket. The outer jacket includes a plurality of outer jacket segments in which each outer jacket segment of the plurality is longitudinally adjacent to another outer jacket segment of the plurality. The structural support member includes a first section having a first density, a second section distal to the first section and having a second density, and a third section distal to the second section and having a third density, such that the second density being higher than the first and third densities. The second section of the structural support member is longitudinally aligned with a junction between two outer jacket segments of the plurality of outer jacket segments.

An endotracheal tube apparatus to treat a patient comprising an endotracheal tube and a hub connection fitting; the endotracheal tube insertable into a trachea of the patient; the hub connection fitting connectable to the endotracheal tube; a ventilation passageway extending through the hub connection fitting and a ventilation lumen of the endotracheal tube; a plurality of ports joined with the hub connection fitting, the plurality of ports comprising at least a first port and a second port; a first passageway extending within the hub connection fitting, the first passageway in fluid communication with the first port; a second passageway extending within the hub connection fitting, the second passageway in fluid communication with the second port; a third passageway extending within the hub connection fitting and a secondary lumen of the endotracheal tube.

An approach for assembling a platform drug delivery device includes providing a set of base components and identifying, based on at least one desired characteristic of the platform drug delivery device, a rear sub-assembly for the drug delivery device from a group of rear sub-assemblies. The identified rear sub-assembly is selected, and a front sub-assembly is identified based on the at least one desired characteristic from a group of front sub-assemblies. The identified front-assembly is selected, and the drug delivery device is assembled using the set of base components, the rear sub-assembly, and the front sub-assembly.

A reservoir device comprising an active agent formulation contained within a reservoir is described. The reservoir is defined by a biodegradable, permeable polymer membrane having a thickness of at least 45 μm. The membrane allows for diffusion of an active agent of the formulation there through when positioned subcutaneously in a body of a subject.

A device is provided for delivering one or more substances within at least one body cavity. The device includes at least one pierceable vial comprising V.sub.sub [ml or mg] of the substances; the vial having at least one fluid discharging outlet port, configured for placement in proximity to the body cavity. The pierceable vial is configured to interface in a sealable manner with at least one pressurized fluid at volume V.sub.PF [ml] and pressure P.sub.PF [barg]. The device, upon actuation, permits the pressurized fluid to enter into the pierceable vial via the at least one fluid inlet port, entrains the substances, and delivers the substances through the fluid discharging outlet port to within the body cavity in the form of at least one selected from a group consisting of drops, droplets, stream, aerosol and any combination thereof.

A patient interface is disclosed which is comfortable for the user to wear and includes at least in part a moisture permeable or breathable area in the body of the patient interface. In another embodiment the patient interface is a strapless mask that is moulded to fit the contours of a user's face and maximise the mask-to-skin seal. An adhesive material is bonded to the mask cushion and is stamped in place to form substantially the same shape as the cushion such that it fits the facial contours of the user.

Provided are a feeding accessory and a feeding accessory. The feeding accessory includes a nipple cap, a nipple head, a delivery tube, and a blocking member. The nipple cap has a bowl-inverted shape. The nipple head is provided in a center of an outer arc surface of the nipple cap. One end of the delivery tube is provided in a center of an inner arc surface of the nipple cap and is in communication with the cavity of the nipple head. The blocking member is provided with a liquid conducting through hole along a thickness direction of the blocking member, The blocking member is configured to be plugged into an opening of a bottle. At least the nipple cap, the nipple head, and the blocking member are made of silicone.