A sensor insertion assembly includes: a sensor insertion device comprising a needle member configured to be inserted in a living body together with a biological information sensor and to be pulled out of the living body after leaving a distal end side of the sensor in the living body; and a base plate detachably attached to a first end side of the sensor insertion device, the base plate comprising a clamp portion configured to move so as to clamp a proximal end side of the sensor extending to an outside of the living body after pulling out the needle member and along with an operation of detaching the sensor insertion device from the base plate.

Provided are systems, methods, and devices for biomarker shaping and sleep profile enhancement. Systems include a plurality of electrodes configured to be coupled to a brain of a user and configured to obtain a plurality of measurements from the brain of the user, and an interface configured to obtain the plurality of measurements from at least the plurality of electrodes. Systems also include a processing device comprising one or more processors configured to generate a first target sleep profile for the user based, at least in part, on the plurality of measurements and a plurality of biomarkers, the processing device being further configured to generate a plurality of stimulus parameters based, at least in part, on the target profile.

The present invention relates to devices, systems, and methods for controlling the concentration of potassium in dialysate in a closed loop potassium control system. The devices, systems, and methods can be compatible with any dialysis system including sorbent-based dialysis systems, single pass dialysis systems, or other multi-pass dialysis systems. The systems can use closed loop potassium control over potassium concentration in the dialysate to reduce the probability of patient arrhythmias. The potassium concentration can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated for optimizing the potassium concentration in the dialysate.

The invention relates to a motor with a stator (2, 2′) and a rotor (1, 1′), which can be driven about an axial direction (4). The invention is characterized in that at least one of the stator and the rotor, in particular the stator, which has a winding arrangement that can be supplied with a current, can be radially compressed and expanded.

An antibiotic-eluting article for implantation into a mammalian subject, produced by an additive manufacturing process wherein a polymeric material is concurrently deposited with a selected antibiotic. The additive manufacturing process is a fused deposition modeling process. The antibiotic-eluting article may be temporary or permanent orthopaedic skeletal component, an orthopaedic articulating joint replacement component, and/or an external hard-shell casing for an implantable device. One or more bone-growth-promoting compositions may be concurrently deposited with the polymeric material. The implantable device may be a cardiac pacemaker, a spinal cord stimulator, a neurostimulation system, an intrathecal drug pump for delivery of medicants into the spinal fluid, and infusion pump for delivery of chemotherapeutics and or anti-spasmodics, an insulin pump, an osmotic pump, and a heparin pump.

The present invention relates to an implantable apparatus for obtaining urinary control and emptying of the urinary bladder, thereby preventing from or treating involuntary urinary retention. In general terms, the apparatus comprises an expandable member adapted to be implanted inside the urinary bladder of the patient for discharging urine, and a control device for controlling the volume of the expandable member. The control device is adapted to be connected to the expandable member through the wall of the urinary bladder.

An arteriovenous graft system is described. The arteriovenous graft system includes an arteriovenous graft that is well suited for use during hemodialysis. In order to minimize or prevent arterial steal, at least one valve device is positioned at the arterial end of the arteriovenous graft. In one embodiment, for instance, the arteriovenous graft system includes a first valve device positioned at the arterial end and a second valve device positioned at the venous end. In one embodiment, the valve devices may include an inflatable balloon that, when inflated, constricts and closes off the arteriovenous graft. If desired, a single actuator can be used to open and close both valve devices.

A system for coupling a first space within a body of a patient with a second space within the body of the patient including a flow connector insertable into the first and second spaces within the body and having a conduit having a wall forming a lumen therein and first and second orifices. A first retention member is engageable with a first portion of the first space within the body and has a first opening, and the flow connector is positioned within the first opening. A second retention member is engageable with the second space within the body, the second retention member has a second opening and the flow connector is positioned within the second opening. The second retention member interlocks with the first retention member.

The Peritoneal Conduit is a medical device composed of tubing with an integrated collar made of a flexible and non-absorbable material for surgical implantation to create a conduit for passage of a catheter between two body cavities. The Peritoneal Conduit has a hollow center that spans from one end (shorter proximal portion) to the other end (longer distal portion). The catheter that will be being placed through the Peritoneal Conduit will enter into the proximal portion and will pass through the hollow center of the Peritoneal Conduit to emerge from the distal portion. The catheter is then secured to the Peritoneal Conduit using one suture that is tied around the groove in the proximal portion of the Peritoneal Conduit. The Peritoneal Conduit itself is secured in placed using two sutures that are placed through the integrated collar at the junction of the proximal and distal portions of the Peritoneal Conduit.

A pass-through assembly including a first wall 110d having oppositely-directed inner and outer sides, 112, 114, the first wall 110d defining a first opening 116 extending from the inner side 112 to the outer side 114; an elongated structure 118 extending into the opening 116 from the outer side 114 of the first wall 110d; a first material 130 contacting the first wall 110d and the elongated structure 118 so as to at least partially seal the opening 116, and a second material 140 different from the first material 130, the second material 140 overlying the first material 130 on the outer side 114 of the wall 110d, the second material 140 adhering to the elongated structure 118 and the first wall 110d, the second material 140 having at least one physical property different than a corresponding physical property of the first material 130.