A droplet delivery device with a small volume drug ampoule and related methods for delivering precise and repeatable dosages to a subject for pulmonary use is disclosed. The droplet delivery device is configured to facilitate the ejection of small, e.g., single use, volumes of a therapeutic agent. The droplet delivery device includes a housing, a mouthpiece, a small volume drug ampoule, an ejector mechanism, and at least one differential pressure sensor. The delivery device is automatically breath actuated by the user when the differential pressure sensor senses a predetermined pressure change within housing. The droplet delivery device is then actuated to generate a plume of droplets having an average ejected particle diameter within the respirable size range, e.g, less than about 5-6 μm, so as to target the pulmonary system of the user. The small volume drug ampoule may include a reservoir which comprises an internal flexible membrane separating two internal volumes, a first background pressure fluid volume and a second drug volume.

A peritoneal dialysis system comprises a cycler including an air pump; a heater housing including a heater and an expandable bladder in fluid communication with the air pump, wherein the heater housing is sized to receive a heater bag between a wall of the housing and the expandable bladder; a plurality of nesting containers configured for fluid communication with the air pump a disposable set operable with the cycler and including the heater bag and a plurality of fluid supply bags for placement within the plurality of nesting containers; and a control unit programmed to control the air pump and the heater.

The present disclosure provides aerosol delivery devices having a variety of configurations and arrangements. Some aspects of the disclosure provide aerosol delivery devices having a first pump configured to deliver a flow of air; a second pump configured to deliver a flow of liquid; and a nozzle configured to receive the flow of air and the flow of liquid and output the liquid in an atomized form.

A therapeutic vaporizer inhalation bag attachment system with an integrated valve is disclosed. The attachment system includes a body having a lumen extending between the two openings of the body, a bag coupling, and a valve positioned within the lumen. A method of using the inhalation bag attachment system is also disclosed.

An anal irrigation system with a box for a reservoir is provided. The reservoir may be for one-time use and disposed of after use. The box is provided with means for pressing so that the box can be used to displace liquid from a reservoir in an easy and convenient way. Also provided is a box with means for pressing so as to displace liquid from a reservoir. Also provided is an anal irrigation system without reservoir and where the box is provided with an inflatable lung, which is inflated for displacing the liquid from the box.

A cuff assembly for a tracheostomy tube includes an outer bladder and an inner cuff. The inner cuff is positioned adjacent to the tracheostomy tube, and the outer bladder is positioned adjacent to the inner cuff. The outer bladder is made with a less elastic material and operates at a higher relative pressure. The inner cuff is made with a more elastic or hyper-elastic material and operates at a lower relative pressure. A secondary airflow opening is formed on a lateral wall of the tracheostomy tube between the cuff assembly and a main distal opening of the tracheostomy tube.

A wearable breast pump system is provided. The wearable breast pump system can include a housing having a pump, a breast flange, and a milk container. The pump can form part of a closed loop system that drives a separate, deformable diaphragm to generate negative air pressure. The diaphragm can be removably mounted on a breast shield.

A chilled-air inhaler device for the alleviation of respiratory symptoms includes a body containing a hollow chamber through which air is forced or drawn past at least an air-chilling surface. In an embodiment the air-chilling surface may include water ice. Connected to the body and hollow chamber at one end is a mouthpiece including an opening that connects from environmental air outside of the hollow chamber to the hollow chamber. Connected to the hollow chamber at a second end is an inlet which connects to a source of air. In an embodiment, the inlet may connect to an external device such blower or nebulizer.

A nasal respiratory mask for a high flow oxygen therapy apparatus, comprising: a mask frame; and a mask cushion on the mask frame for contacting and substantially sealing against a face of a patient, the mask frame and mask cushion defining a nasal breathing cavity, wherein the mask frame comprises: a hose attachment portion for attaching a hose for delivering a supply of oxygen enriched air to the patient; and a mask aperture for restricting the flow of gas from the nasal breathing cavity directly to ambient, wherein the mask aperture maintains a positive end-expiratory pressure (PEEP) in the nasal breathing cavity of between 0.2 kPa and 1 kPa during the administering of high flow oxygen therapy to the patient.

Methods, systems, and devices are provided for generating a mist. In one embodiment, a fluid delivery device is provided that includes a housing, a fluid vaporizer disposed within the housing and configured to receive fluid and to produce an aerosol mist of liquid particles from the fluid, and a pump configured to accelerate the aerosol mist produced by the fluid vaporizer. Methods are provided for producing a mist, and the methods can include delivering a fluid to a fluid vaporizer that generates a first mist. The fluid vaporizer delivers the mist to a pump that generates a second mist from the first mist.