Disclosed are methods, apparatus and systems for treating a respiratory disorder in a patient. The apparatus comprises a pressure generator configured to generate a flow of air so as to provide ventilatory support to the patient; a transducer configured to generate a flow signal representing a property of the flow of air; and a controller configured to analyse the flow signal to estimate the inspiratory volume and the expiratory volume of a breath of the patient and servo-control the degree of ventilatory support to adjust an estimated tidal volume toward a target tidal volume. A gain of the servo-control is dependent on a difference between the estimated inspiratory volume and the estimated expiratory volume. The method comprises operating an apparatus or system in a similar manner.

One implementation of the present disclosure is a method for dynamically controlling an alarm of a negative pressure wound therapy (NPWT) device, according to some embodiments. In some embodiments, the method includes initiating NPWT, comparing an initial pump duty to a threshold value to determine a dressing application quality, monitoring a leakage rate of the NPWT, setting a leak threshold value based on the dressing application quality, determining leakage event occurrences in response to the leakage rate exceeding the leak threshold value at multiple times, adjusting the leak threshold value based on at least one of a number of the leakage events over the time period, a time duration between sequentially occurring leakage events of the leakage events, and the dressing application quality, and causing a user interface device to display a leak alert in response to the leakage rate exceeding the adjusted leak threshold value.

A plurality of flow rate values associated with pressurized air directed to an airway of a user of a respiratory therapy system is received. A plurality of pressure values associated with the pressurized air directed to the airway of the user is received. A first time associated with a first breath of the user and a second time associated with a second breath of the user are identified. The plurality of flow rate values is filtered based at least in part on the identified first time and the identified second time. The filtering produces a subset of the plurality of flow rate values. An intentional leak characteristic curve for the respiratory therapy system is determined using at least two of the subset of the plurality of flow rate values and the corresponding pressure values for said at least two of the subset of the plurality of flow rate values.

A closed circulation system test apparatus independently sets the amount of a liquid such as a dialysate for a blood purification device, facilitates management of operations of multiple pumps, and is capable of evaluating performance for removing wastes in blood and lifespan performance of membranes. The closed circulation system test apparatus includes: a blood sending line for sending blood from the blood bag to the blood purification device via a blood pump; a blood returning line for sending blood exiting from the blood purification device to the blood bag via a resistance imparting means; a filtrate line for sending the filtrate exiting from a dialysate outlet of the blood purification device to the replacement fluid container via a filtrate pump; and a dialysate line for sending, via a dialysate pump, dialysate or replacement fluid from the replacement fluid container to a dialysate inlet of the blood purification device.

Embodiments of a reduced pressure system and methods for operating the system are disclosed. In some embodiments, the system can include one or more processors responsible for various functions associated with various levels of responsiveness, such as interfacing with a user, controlling a vacuum pump, providing network connectivity, etc. The system can present GUI screens for controlling and monitoring its operation. The system can determine and monitor flow of fluid in the system by utilizing one or more of the following: monitoring the speed of a pump motor, monitoring flow of fluid in a portion of a fluid flow path by using a calibrated fluid flow restrictor, and monitoring one or more characteristics of the pressure pulses. The system can provide external connectivity for accomplishing various activities, such as location tracking of the system, compliance monitoring, tracking of operational data, remote selection and adjustment of therapy settings, etc.

A computer-implemented method comprises providing a fluid circuit comprising fluid pathways configured to mount and associate with a durable processing device comprising a pressure sensor in communication with a controller and a fluid pathway. A container is connected to the pressure sensor and may receive a volume of fluid. A change in pressure values between a first and second time is measured from when the volume of fluid is not in communication with the pressure sensor to when the volume of fluid is in communication with the pressure sensor, the volume of fluid within the container or a presence or absence of a fluid connection to the fluid pathway based on the change in pressure values is determined, and a response action is executed if the volume of fluid within the container is not within an authorized volume range for the time period, or if a fluid connection is unauthorized.

Provided is a mask fitting level determination device that has a significantly simple component configuration, that can be driven by a battery, that can be reduced in size to a palm size, that is inexpensive, that is operated by a simple operation method, and that does not require proficiency for accurate measurement. The mask fitting level determination device includes: a mask inner pressure detection unit 2 that is inserted between a face surface F of a mask wearing person and a worn mask 1; and a circuit control unit that sets a predefined threshold value in accordance with strength of breathing of the mask wearing person and determines a fitting level on the basis of a reference pressure value and a mask inner pressure value measure by the mask inner pressure detection unit 2; and a display unit 3 that displays the fitting level determined by the circuit control unit to the mask wearing person.

A respiratory therapy apparatus is operable to deliver multiple types of therapy to a patient. The apparatus includes a main housing and a nebulizer tray that selectively attaches to a bottom of the main housing. The apparatus also includes a filter housing unit having an antenna surrounding a pneumatic passage and a transponder chip coupled to the antenna. The main housing has also has an antenna that surrounds a respective pneumatic passage of a main outlet port of the apparatus. The main housing includes a reader that controls communication between the antennae. The main housing of the apparatus also has a pivotable hose support plate, a firmware upgrade port underneath part of the top wall of the housing, and a graphical user interface (GUI) that displays various user inputs for control of the apparatus and that displays various alert conditions that are detected.

A volume of a wound is estimated using a dynamic pressure response measured during instillation of fluid to the wound using a negative pressure wound therapy system. A previously estimated wound volume may be used to detect and prevent overfill of fluid to the wound during future instillation events. For example, real-time pressure measurements may be compared to model data representative of expected pressure at a wound having a volume equal to the previously estimated wound volume, with instillation being stopped if the observed pressure varies from the expected pressure. A comparison of a total volume of fluid instilled to the wound may also be compared to the previously estimated wound volume to prevent overfill. The comparison of wound volume estimated based on an instillation event may also be compared to a wound volume estimated using other methods to provide a higher confidence wound volume estimate.

Dialysis systems comprising actuators that cooperate to perform dialysis functions and sensors that cooperate to monitor dialysis functions are disclosed. According to one aspect, such a hemodialysis system comprises a user interface model layer, a therapy layer, below the user interface model layer, and a machine layer below the therapy layer. The user interface model layer is configured to manage the state of a graphical user interface and receive inputs from a graphical user interface. The therapy layer is configured to run state machines that generate therapy commands based at least in part on the inputs from the graphical user interface. The machine layer is configured to provide commands for the actuators based on the therapy commands.