Monitors for evaluating airway procedures, particularly in a pre-hospital environment, are described herein. In an example method, an airway parameter of an individual receiving assisted ventilation is detected by an airway sensor. A monitor determines a metric based on the airway sensor. Further, the monitor performs an action based on the metric.

Adaptive modification and presentment of user interface elements in a computerized therapeutic treatment regimen. Embodiments of the present disclosure provide for non-linear computational analysis of cData and nData derived from user interactions with a mobile electronic device executing an instance of a computerized therapeutic treatment regimen. The cData and nData may be computed according to one or more artificial neural network or deep learning technique to derive patterns between computerized stimuli or interactions and sensor data. Patterns derived from analysis of the cData and nData may be used to define an effort metric associated with user input patterns in response to the computerized stimuli or interactions being indicative of a measure of user engagement or effort. A computational model or rules engine may be applied to adapt, modify, configure or present one or more graphical user interface elements in a subsequent instance of the computerized therapeutic treatment regimen.

Provided herein are dry powder formulations comprising epinephrine alone or in combination with at least one enabling agent suitable for nasal application. Also provided are unit dose forms and devices comprising such formulations and methods of using such formulations for the treatment of various conditions including anaphylaxis, anaphylactoid reaction, respiratory conditions, hemodynamic collapse, and for administration during cardiopulmonary arrest and other life-threatening conditions.

A system for creating separation between biological surfaces may comprise a hollow body configured for delivery of a fluid to a target location, a fluid supply in fluid-communication with the hollow body, a control element configured to control the delivery of a fluid through the hollow body, at least one first sensor configured to measure at least one parameter of the fluid flowing through the hollow body, at least one second sensor configured to measure at least one parameter of an environment of the hollow body, a feedback control module configured to receive information from one or more of the at least one first sensor or the at least one of the second sensor to control at least one operational function of the system.

Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a pump assembly and a wound dressing configured to be positioned over a wound. The pump assembly and the wound dressing can be fluidically connected to facilitate delivery of negative pressure to a wound via a fluid flow path. The system can be configured to efficiently deliver negative pressure and to detect and indicate presence of conditions, such as a blockage in a fluid flow path. Monitoring of the conditions can be performed by detecting a level of activity of a pump of the pump assembly.

A method and apparatus for determining gastric content volume. The internal temperature of the contents of the stomach is measured at least one predetermined time t after the patient is fed, and the gastric volume determined from the temperature. In preferred embodiments, a known volume of water at a known temperature is injected into the stomach, and the temperature of the stomach contents is measured after the stomach temperature has stabilized. An apparatus for performing the method, in which continuous measurement is possible without disturbing the patient's feeding schedule, and a method for using the inventive method in the control of an automatic feeding apparatus, are also disclosed.

A blood treatment device includes an extracorporeal blood circuit, dialyzer and dialysis fluid circuit. The blood circuit and dialysis fluid circuit are separated from each other by a membrane in the dialyzer. A weighing device measures and monitors the weight of a bag containing a fluid. A fluid pump pumps fluid out of and into the bag. A control unit interrupts fluid supply by stopping the pump when a weight variation of the bag occurs and temporarily maintains the interruption at least until the malfunction disappears, and automatically restarts the fluid supply if the bag or the weight of the bag stabilizes within a predetermined time and the weight variation does not exceed a predetermined value. The control unit generates an alarm if the bag or weight of the bag does not stabilize within a predetermined time and/or if the weight variation exceeds a predetermined value.

Some aspects of the present disclosure relate to a drive mechanism for a drug delivery device. The drive mechanism includes: a piston rod to operably engage with a piston of a cartridge to displace the piston in a distal direction during a dose dispensing action, at least one actuation member mechanically coupled with the piston rod to induce a distally directed displacement of the piston rod when actuated by a user, a control to ascertain at least one predefined condition of use, and at least one interlock member coupled with the control to mechanically obstruct displacement of the piston rod if the condition of use is not fulfilled.

The present disclosure relates to integrated systems, methods and apparatuses for assisting individuals in managing acute life-threatening conditions. A system in accordance with the current disclosure may comprise an electronic circuit configured to be attached to a container of a medication and one or more devices in communication with the electronic circuit in a private network. In an aspect, the one or more devices may work in concert to determine the safety level of an individual based on predetermined usage settings. In some aspects, the system may be configured to determine whether a medication would expire before its manufactured expiry date. In another aspect, the system may assist an individual in locating a medication. In a further aspect, the system may determine whether an individual is having an anaphylactic reaction. In some aspects, the system may detect a known allergen and alert the individual.

A heart support system is provided includes a control unit and sound-generating devices, said control unit configured to detect and process alarm events and to carry out control tasks in the heart support system. The heart support system further includes a storage device configured to store one or more defined alarm signal time curves and one or more alarm priorities. Each alarm signal time curve and each alarm priority is assigned to an alarm event. A sound-generation controller is configured such that when an alarm event is detected, the controller overlays a volume time curve onto the alarm signal time curve assigned to the alarm event in the storage device, said volume time curve based on the alarm priority assigned to the respective alarm event in the storage device and the length of time since the detection of the alarm event.