An injection device suitable for use with infants is disclosed. The injection device is formed from a body shield member and a cylindrical handle. The body shield member includes a concave flange at the base, which is pressed against the patient's limb and reduces local compression at the needle insertion site. The injection device also has a softer form and operates through a pressing motion. A catch member is located in the cylindrical handle, and is deployed upon fully depressing the handle. Once the handle returns to its starting position, the catch member prevents the handle from being depressed a second time and permitting the used needle to be exposed.

The invention relates to the field of inhalation devices for liquids. In particular, the invention relates to a fixture for a nebulizing nozzle to be used in such an inhalation device. A nozzle fixing assembly (1) for an inhalation device, comprising an elastically deformable seal element (2), having a continuous opening (3) capable of receiving a nozzle body (4), said seal element (2) and said nozzle body (4) each having a high pressure side (2A, 4A) and an outlet side (2B, 4B); and a pressure element (5) with a high pressure side (5A), said side being arranged to face the high pressure side (2A) of the seal element (2); wherein (i) the high pressure side (2A) of the seal element (2) is substantially flat, and (ii) the high pressure side (5A) of the pressure element (5) is chamfered in a way that, in the assembled state, the distance between these high pressure sides (2A, 5A) is higher in a central region (C) than in a peripheral region (P).

Systems, devices, and methods described herein relate to delivery of therapeutic agents. Such systems and devices can include needle-based delivery systems, in which a throttling assembly is configured to control a rate or needle insertion and/or a rate of drug extrusion.

Disclosed herein is a valve assembly comprising a male luer end portion and a female luer end portion and a passage for the transfer of fluids extending between the male and female luer end portions, valve means movable between a first position, in which the passage is closed, and a second position, in which the passage is open, biasing means for biasing the valve means toward the first position, and actuating means extending into the male luer end portion and coupled to the valve means to actuate the valve means when a female luer end portion of a medical accessory is engaged with the male luer end portion.

The present invention relates to an inhaler which is appropriate for delivery of medicament in dry powder form used in respiratory diseases, particularly in asthma and chronic obstructive pulmonary disease (COPD). In addition, the present invention relates to an inhaler which includes a blister package appropriate for carrying the medicament in dry powder form and used to realize an effective inhalation.

Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.

Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.

A needle guard device mountable to a pre-filled syringe in its ready-to-fill state. The device includes a device shield interconnected to a lock collar with flexible member and biased to move relative to the lock collar. The lock collar interfaces with the syringe neck to attach the device to the syringe. As the device shield moves proximally, rotation arms of the lock collar interact with angled cutouts in the device shield, causing the device shield to rotate relative to the lock collar and disengaging one or more keys on the device shield from one or more keyways in the lock collar triggering the device shield to move from a first configuration in which the device shield is retractable to expose a syringe sharp to a second configuration in which the device shield is fixedly positioned to cover the syringe sharp.

Disclosed herein is a valve assembly comprising a male luer end portion and a female luer end portion and a passage for the transfer of fluids extending between the male and female luer end portions, valve means movable between a first position, in which the passage is closed, and a second position, in which the passage is open, biasing means for biasing the valve means toward the first position, and actuating means extending into the male luer end portion and coupled to the valve means to actuate the valve means when a female luer end portion of a medical accessory is engaged with the male luer end portion.

Drug products adapted for nasal delivery, comprising a pre-primed device filled with a pharmaceutical composition comprising an opioid receptor antagonist, are provided. Methods of treating opioid overdose or its symptoms with the inventive drug products are also provided.