An apparatus is provided to change the absolute humidity of a flow of air for delivery to an entrance of the airways of a patient, the change being compared to the absolute humidity of ambient air. The apparatus has a reservoir configured to hold a volume of liquid. A heating element creates vapour from the liquid. A chamber is provided to mix the flow of air with the vapour. The apparatus has a body having a first wall structure with a chamber inlet port. A closure element having an air inlet port for pneumatically connecting to a source of the flow of air is secured to the body to provide a sealed gas flow path between the air inlet port and the chamber inlet port, and a liquid trap in the gas flow path.

A self-righting device is disclosed having a support body for supporting a medicament delivery device, where the support body has a mass, a center of gravity (G) and a shape such that the self-righting device, when positioned on a substantially horizontal surface, moves from an unbalanced position to an upright position. The self-righting device can also have a mechanical adaptor configured for attachment to the support body and for holding an elongated medicament delivery device at an angle less than 30 degrees from a vertical axis when the self-righting device is in the upright position. An assembly of a self-righting device and an elongated medicament delivery device is also provided.

An apparatus includes a housing having a gas flow generator for generating a flow of breathing gas and a humidifier disposed therein having a chamber for housing a volume of water. The chamber has a top opening for providing the volume of water therein. The apparatus further includes a lid coupled to the housing that is movable between a first position wherein the lid covers the top opening and a second position wherein the lid does not cover the top opening. The apparatus also includes a passage which extends from a first end positioned and structured to receive the flow of breathing gas from the gas flow generator to an opposite second end positioned on the lid and structured to expel the flow of breathing gas into the chamber. An outlet for conveying the flow of breathing gas from the chamber out of the housing is positioned on the housing.

An apparatus for humidifying a flow of breathable gas includes a water reservoir and a water reservoir dock forming a cavity structured and arranged to receive the water reservoir in an operative position. The water reservoir comprises a reservoir base including a cavity structured to hold a volume of water, the reservoir base including a main body and a thermally conductive portion provided to the main body. The thermally conductive portion comprises a combined layered arrangement including a metal plate and a thin film, the thin film comprising a non-metallic material and including a wall thickness of less than about 1 mm. The thin film is adapted to form at least a bottom interior surface of the water reservoir exposed to the volume of water, and the metal plate is adapted to form a bottom exterior surface of the water reservoir.

A patient interface comprising a cushion having a nasal plenum chamber, an oral plenum chamber, and a passage formed between the nasal and oral plenum chambers. The passage is configured to allow airflow to pass between the nasal and oral plenum chambers. The cushion also includes a valve including valve body and an adjustment structure that is positioned between the nasal chamber and the oral chamber and is movable relative to the valve body. The adjustment structure is movable between an open position that is configured to allow airflow between the nasal plenum chamber and the oral plenum chamber, and a closed position configured to limit airflow between the nasal plenum chamber and the oral plenum chamber. The adjustment structure is configured to allow airflow through a nasal vent in the closed position and is configured to limit airflow through the nasal vent in the open position.

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface. The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage with a surface. In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components.

Disclosed are methods, apparatus and systems for treating a respiratory disorder in a patient. The apparatus comprises a pressure generator configured to generate a flow of air so as to provide ventilatory support to the patient; a transducer configured to generate a flow signal representing a property of the flow of air; and a controller configured to analyse the flow signal to estimate the inspiratory volume and the expiratory volume of a breath of the patient and servo-control the degree of ventilatory support to adjust an estimated tidal volume toward a target tidal volume. A gain of the servo-control is dependent on a difference between the estimated inspiratory volume and the estimated expiratory volume. The method comprises operating an apparatus or system in a similar manner.

Modular ventilatory support systems and methods are disclosed in which a user may transition the system between a stationary configuration, an extended range configuration, and a stand-alone configuration. The modular components of the system include a compressor unit, a ventilator which may dock with the compressor unit, and a patient interface which may be connected to either the compressor unit or the ventilator unit. By rearranging these modular components into different configurations, mobility and duration of use may be optimized to fit the present needs. In the stationary configuration, mobility is most restricted, but duration of use is maximized. In the extended range configuration, mobility is enhanced, with duration of use limited by the battery power of the ventilator. In the stand-alone configuration, mobility is maximized, with duration of use limited by battery power of the ventilator and the quantity of an external gas supply.

A patient interface for supplying a flow of breathable gas to the airways of a patient may comprise a heat and moisture exchanger (HME). The HME may be positioned in a flow path of the flow of breathable gas. The HME may absorb heat and moisture from gas exhaled by the patient and the incoming flow of breathable gas to be supplied to the patient's airways may be heated and moisturized by the heat and moisture held in the HME.

Systems and methods producing a customised patient respiratory interface are disclosed. Data representative of one or more landmark features of a head of a human is obtained. One or more landmark feature locations of the landmark features are identified based on the data. A set of manufacturing specifications for production of the patient respiratory interface component is determined based on the one or more landmark feature locations. The patient respiratory interface component is produced based on the set of manufacturing specifications.