A reservoir configured to retain a volume of liquid for use in an apparatus for humidifying a flow of pressurised air comprises a base portion and a lid portion. The reservoir may be configured to improve its level of thermal contact to the heater plate using the flow of pressurised air. The reservoir may be configured to improve thermal contact between the reservoir and the heater plate by pre-compression upon engagement of the reservoir with the humidifier. The reservoir may comprise a removable intermediate portion, which may include the inlet tube and/or the outlet tube, for improved access for cleaning. The reservoir may also be configured to prevent overfilling. Overfill prevention features in the reservoir may include defined flow egress paths and/or formation of air locks.

A patient interface includes: a plenum chamber; a seal-forming structure; a positioning and stabilising structure; a plenum chamber insert configured to be positioned and retained within the plenum chamber; and a vent structure; wherein the plenum chamber insert has a plenum chamber insert port; wherein the plenum chamber insert has an exterior surface configured to be positioned adjacent to an interior surface of the plenum chamber; wherein when the plenum chamber insert is positioned and retained within the plenum chamber, a radial channel is formed by the interior surface of the plenum chamber and the exterior surface of the plenum chamber insert such that gas is able to pass between a patient-proximal side plenum chamber insert and a patient-distal side of the plenum chamber insert via the radial channel during use.

A respiratory device, such as a ventilator, for use in treating respiratory disorders and for preventing respiratory disorders. The respiratory device is configured to be powered from a range of different power sources including an internal battery, an external battery, AC power source or a DC power source. The device may be electrically connectable to a plurality of external batteries in a series and the power from each external battery is used sequentially along the series. A controller of the respiratory device is configured to detect the connection of the different power sources and control use of the different power sources using a power priority scheme. The controller may determine an estimate of the total available battery capacity from all the electrically connected batteries and display the total battery capacity on a user interface display of the device.

A humidifier includes a base configured to retain a body of liquid therein, a top cover, and a seal disposed between the top cover and the base. At least a portion of the base is constructed of a heat conducting material. The top cover defines both an inlet and an outlet communicated with an interior of the base. The inlet is configured to receive pressurized breathable gas and the outlet is configured to deliver the pressurized breathable gas with added humidity.

A water reservoir includes a water reservoir base configured to hold a volume of water to be used for humidification of pressurized breathable air, a water reservoir lid connected to the water reservoir base, and a compressible resilient portion configured to seal between the water reservoir base and the water reservoir lid. The base and the lid are movable relative to one another when connected whilst maintaining sealing therebetween due to the compressible resilient portion. A retainer is configured to secure the water reservoir to a water reservoir dock, and has a protrusion or recess to releasably engage one another when the water reservoir is received in the dock, with a reaction force to compression of the compressible resilient portion urging the protrusion and the recess into engagement with one another.

A chamber (1) and an air conduit (7) connecting a liquid surface retaining hole (5) with an air hole (6) for supplying air from the outside of an electrostatic atomizer (50) to the chamber (1) are provided. When the liquid surface retaining hole (5) is blocked, the liquid supply from a liquid supplying section (3) to the chamber (1) will be stopped. The air conduit (7) has bent sections (8), and a space (10) for holding the liquid is formed in the air conduit (7).

A blower unit for use as part of an integrated blower/humidification system is described. The blower unit has an outer casing, which encloses and forms part of the blower unit, the casing including an air inlet vent. The blower unit further includes a humidifier compartment for receiving a humidifier unit with a separate gases inlet and outlet, the compartment having a heater base for heating the contents of the humidifier unit. The compartment also has a blower inlet port which aligns with the humidifier unit inlet in use, the blower providing a gases path through the casing between the inlet vent and the inlet port. The blower unit also includes a fan for providing a pressurised gases stream along the gases path, and a power supply unit for powering the fan. The gases path is routed over the power supply unit in order to provide a cooling air flow.

Provided are methods for improving resuspendability of a paliperidone palmitate extended-release injectable suspension within a syringe, for reducing a force required for injection of a paliperidone palmitate extended-release injectable suspension, or for reducing the likelihood of incomplete injection of a paliperidone palmitate extended-release injectable suspension comprising maintaining the syringe in a desired orientation during shipping of the syringe that varies from the orientation of the syringe during pre-shipping storage. Also provided are populations of syringes that respectively contain paliperidone palmitate extended release injectable suspension, wherein each of the syringes have been shipped to a destination, and the syringes were each maintained in a desired orientation during shipping of the syringe that varies from the orientation of the syringe during pre-shipping storage. The present disclosure also provides pharmaceutical products comprising a paliperidone palmitate extended-release injectable suspension within a syringe for administration to a patient suffering from schizophrenia, wherein the syringe has undergone pre-shipping storage and has been shipped, and wherein the syringe has been maintained in an orientation during the shipping that varies from the orientation of the syringe during pre-shipping storage.

A patient interface includes: a plenum chamber; a seal-forming structure; a positioning and stabilising structure; a plenum chamber insert configured to be positioned and retained within the plenum chamber; and a vent structure; wherein the plenum chamber insert has a plenum chamber insert port; wherein the plenum chamber insert has an exterior surface configured to be positioned adjacent to an interior surface of the plenum chamber; wherein when the plenum chamber insert is positioned and retained within the plenum chamber, a radial channel is formed by the interior surface of the plenum chamber and the exterior surface of the plenum chamber insert such that gas is able to pass between a patient-proximal side plenum chamber insert and a patient-distal side of the plenum chamber insert via the radial channel during use.

A blower unit for use as part of an integrated blower/humidification system is described. The blower unit has an outer casing, which encloses and forms part of the blower unit, the casing including an air inlet vent. The blower unit further includes a humidifier compartment for receiving a humidifier unit with a separate gases inlet and outlet, the compartment having a heater base for heating the contents of the humidifier unit. The compartment also has a blower inlet port which aligns with the humidifier unit inlet in use, the blower providing a gases path through the casing between the inlet vent and the inlet port. The blower unit also includes a fan for providing a pressurised gases stream along the gases path, and a power supply unit for powering the fan. The gases path is routed over the power supply unit in order to provide a cooling air flow.