A respiratory pressure therapy (RPT) device is disclosed for treatment of respiratory-related disorders. The RPT device includes a pressure generator, a pneumatic block, a chassis and a device outlet for delivering a supply of flow of gas to a patient interface. The RPT device also comprises an integrated humidifier including a water reservoir. An RPT device is also disclosed that includes a wireless data communication interface integrated with the housing and configured to connect to another device or a network.

A patient interface may include: a plenum chamber at least partly defining a patient interface chamber, a seal-forming structure constructed and arranged to form a seal with a region of the patient's face, at least one conduit, at least one conduit connector configured to pneumatically connect the at least one conduit to the plenum chamber to provide a flow of air at a therapeutic pressure to the patient interface chamber for breathing by the patient, and a positioning and stabilising structure to provide a force to hold the seal-forming structure on the patient's head, the positioning and stabilising structure comprising at least one tie, wherein the at least one conduit connector includes an anti-asphyxia valve configured to allow the patient to breath from ambient through their mouth in the absence of a flow of pressurised air.

This aerosol supply device is provided with: an accommodating section (cartridge) that accommodates a liquid; an atomizing unit that atomizes the liquid to generate an aerosol; and an atomizing amount adjusting unit (gyro sensor and control unit) that adjusts the atomizing amount of the atomizing unit. The aerosol supply device is characterized in that the atomizing amount adjusting unit (gyro sensor and control unit) stabilizes the atomizing amount regardless of the inclination of the aerosol supply device within at least a certain range.

A patient interface system to treat sleep disordered breathing of a patient with pressurized gas, comprising: a patient interface; at least one strap; at least one retractor fixedly attached to the patient interface, said at least one retractor connected to the at least one strap and configured to retract the at least one strap without patient actuation; and at least one pad to cushion a rearward portion of the patient's head, said at least one pad having an opening, wherein said at least one strap passes through said opening to allow the at least one pad to move freely relative to said at least one strap.

The present invention relates to a novel nasal spray containing an aqueous solution or a fluid with an anxiolytic or anticonvulsant substance, wherein the nasal spray is characterized in that with the nasal spray, two sprays with each an equivalent, defined volume of the aqueous solution or liquid of the active agent, can be intranasally administered to a patient and wherein the nasal spray allows for an administration, independent of the spatial orientation of the nasal spray in any position of the patient (standing upright, sitting, lying or in any intermediate position). The nasal spray can be used directly without prior activation. Preferably it is apparent from the nasal spray whether a spray or even a second spray has been made with the nasal spray. Preferably, a spray of the nasal spray can be administered one-handed by the patient or a third person. The active agent in the inventive nasal spray is a benzodiazepine or a GABA-receptor agonist, preferably midazolam or a derivative thereof or a salt of these active agents. The nasal spray according to the present invention may be used for sedation, premedication or treatment of patients with claustrophobia, anxiety disorders or panic attacks or for the treatment of convulsions in CNS diseases, particularly in epileptic seizures or other manifestations of seizures (e.g. febrile convulsions). The invention also relates to a method for hermetically sealing an active agent container for use in supplying an nasal spray in accordance with the invention. The invention also relates to a method of detection by localizing the locally precise administration of an active agent in nasal application, as well as a nasal spray, preferably a bi-dose nasal spray, for which, using the cited method of detection, it has been shown both visually (qualitatively) and quantitatively that an orientation-independent, uniform and locally precise administration of the dose of the active agent onto the nasal mucosa of a patient can be achieved. Also provided is a method for airless and air-tight sealing of an active agent container in accordance with the invention.

A CPAP device is configured to deliver a pressurized flow of respiratory gas to a patient's airways and includes a flow generator with a blower configured to pressurize the flow of respiratory gas. A flexible face seal is positioned at an outlet end of a blower discharge path. The flexible face seal includes an aperture and a lip curling inwardly from a perimeter of the flexible face seal. A tub configured to hold a body of water and humidify the pressurized flow of respiratory gas includes a heat conducting base plate and a side wall. The side wall has a substantially flat portion that surrounds an air inlet opening. A base supports both the flow generator and the tub and includes a floor with a heater plate. A laterally positioned guide prevents the tub from being removed from the base in a vertical direction and includes a pair of C-shaped channel portions with open sides that face each other.

A neck strap, a crown strap assembly and a headgear for a breathing mask. The neck strap for a headgear includes a one-piece main body adapted to engage a patient's neck, first and second lower connection portions adapted to connect to first and second lower mask connection straps, and first and second upper connection portions adapted to connect to respective first and second lateral crown straps.

An apparatus for humidifying a flow of breathable gas includes a water reservoir and a water reservoir dock forming a cavity structured and arranged to receive the water reservoir in an operative position. The water reservoir comprises a reservoir base including a cavity structured to hold a volume of water, the reservoir base including a main body and a thermally conductive portion provided to the main body. The thermally conductive portion comprises a combined layered arrangement including a metal plate and a thin film, the thin film comprising a non-metallic material and including a wall thickness of less than about 1 mm. The thin film is adapted to form at least a bottom interior surface of the water reservoir exposed to the volume of water, and the metal plate is adapted to form a bottom exterior surface of the water reservoir.

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self-righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject).

A water reservoir for an apparatus for humidifying a flow of air for delivery to an entrance of the airways of a patient for respiratory therapy includes a reservoir base configured to hold a volume of water, a reservoir lid comprising an inlet and an outlet, a hinge joint to pivotally couple the reservoir lid to the reservoir base for pivotal movement between an open position and a closed position, wherein the reservoir lid and the reservoir base cooperate to form a sealed internal volume at the closed position, and a rotation stop, wherein the rotation stop is arranged between the reservoir lid and the reservoir base at the open position, and wherein the rotation stop is configured and arranged to disconnect the reservoir lid from the reservoir base at the hinge joint when the reservoir lid is over-pivoted beyond the open position.