A manifold assembly for a surgical gas delivery system is disclosed, which includes a manifold body having an inlet port for receiving insufflation gas from a gas source by way of a high pressure regulator, a first outlet port for delivering insufflation gas to a first access port and a second outlet port for delivering insufflation gas to a second access port, a first outlet line valve operatively associated with the first outlet port, wherein the first outlet line valve includes a first electro-mechanical valve actuator for dynamically controlling the flow of insufflation gas to the first access port, and a second outlet line valve operatively associated with the second outlet port, wherein the second outlet line valve includes a second electro-mechanical valve actuator for dynamically controlling the flow of insufflation gas to the second access port.

Disclosed herein is a wearable drug delivery device including a container filled at least partially with a drug including at least one of a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) specific antibody, a granulocyte colony-stimulating factor (G-CSF), a sclerostin antibody, or a calcitonin gene-related peptide (CGRP) antibody. The wearable drug delivery device may include a needle and an insertion mechanism configured to insert the needle into a patient. A fluid pathway connector may define a sterile fluid flowpath between the container and the insertion mechanism. Optionally, a cannula initially disposed about the needle may be included. The cannula may be retained in the patient at an injection site created by the needle after the needle is withdrawn from the patient. Methods of assembly and operation are also provided.

The present invention includes and provides a method of delivering a medicament to an eye of a subject in need thereof a solution, the method comprising: (a) providing droplets containing the medicament with a specified average size and average initial ejecting velocity; and (b) delivering the medicament to the eye, where the droplets deliver a percentage of the ejected mass of the droplets to the eye.

Insufflation systems may provide a continuous flow of insufflation gas to a body cavity. The continuous flow may be directed over the lens of an endoscope received within a cannula to form a protective envelope around the lens and improve visibility. The continuous flow may be supplied by a pressurized gas source. The continuous flow line may be assembled in parallel to an insufflation line running through a standard insufflator configured to provide non-continuous gas flow to the body cavity. The lines may converge upstream of or at the cannula or the insufflation flow may be provided to a separate cannula. Continuous gas flow may be provided by recirculating gas from the body cavity through the cannula Continuous gas flow may be provided by storing gas from the non-continuous insufflation flow in an accumulator and releasing the gas during off phases of the insufflation flow.

A capsule for an aerosol-generating device may include a housing, a filter, and an aerosol-forming substrate. The housing may have a gas-permeable end and an impermeable end. The filter may be disposed within the housing so as to be adjacent to the impermeable end. The aerosol-forming substrate may be disposed within the housing so as to be between the filter and the gas-permeable end. The housing may be configured to facilitate a heating of the aerosol-forming substrate via one of conduction, convection, or both conduction and convection so as to generate an aerosol.

A blood loop system for controlling blood oxygen saturation includes a conduit loop, a pump, a flow cell, a matter source, an aeration chamber, a collection chamber and an oxygen probe. The pump is coupled to the conduit loop and positioned to circulate blood through the conduit loop. The flow cell is positioned to measure a characteristic of the blood circulated through the conduit loop. The matter source includes a gas. The aeration chamber is coupled to the conduit loop and is in fluid communication with the matter source to enable the gas to combine with the blood. The collection chamber is in fluid communication with the aeration chamber and is positioned to receive the blood. The oxygen probe is positioned to measure an amount of oxygen in the blood.

The disclosure relates to medical databases, remote monitoring, diagnosis and treatment systems and methods. In one particular embodiment, a system for remote monitoring, diagnosis, or treatment of eye conditions, disorders and diseases is provided. This method generally includes administering a stream of droplets to the eye of a subject from an ejector device, and storing data related to the administration in a memory of the ejector device. The data may then be monitored and analyzed.

A dialysate mixing machine may be configured to make dialysate on demand using, among other things, a plurality of concentrates in solid tablet form. For example, a prescription may be received by the dialysate mixing machine indicating the particular chemical constituents and amounts of each chemical constituent to be included in the dialysate. Based on the prescription, the dialysate mixing machine can determine the number of tablets required for each chemical constituent (and, e.g., the required amounts of other chemical constituents that are not in tablet form). The tablets are automatically dispensed and mixed with purified water, bicarbonate, and sodium chloride in a mixing chamber to produce the dialysate according to the prescription. The dialysate mixing machine may be used with and/or coupled to a dialysis machine (e.g., a hemodialysis (HD) machine designed for home use) to provide the dialysate on demand for a dialysis treatment.

A capsule for an aerosol-generating device may include a housing defining inlet openings, outlet openings, and internal channels between the inlet openings and the outlet openings. The internal channels are configured to hold an aerosol-forming substrate. The housing is configured to facilitate a heating of the aerosol-forming substrate via conduction and/or convection so as to generate an aerosol.

The electronic system for vaporizing smokable materials for personal inhalation includes two or more heating elements for vaporizing cannabis, tobacco, e-cigarette fluid and other inhalable materials. Includes a power source and two or more heating elements, each connected to a multi-heating-element circuit-switching-element that allows individual control of the duration and amount of heat applied to each heating element. Each heating element applies heat to one smokable material, which can be contained in a cartridge. The multi-heating-element circuit-switching-element can be a slide switch, push button, rotary encoder, pressure switch, infrared switch, a voice activated switch or a graphical user interface attached to a integrated circuit. The power source can be a battery.