In one representative embodiment, a method of perfusing organs in a patient's body is provided. The method comprises isolating the visceral arteries and the visceral veins from blood circulating through the patient's heart and perfusing the visceral arteries, the visceral veins, and the abdominal organs with a perfusion fluid that is fluidly separated from the blood circulating through the patient's heart. While the visceral arteries and the visceral veins are isolated, and the visceral arteries, the visceral veins, and the abdominal organs are being perfused, the patient's blood is allowed to continue to circulate through the heart.

The present disclosure describes a novel therapeutic apheresis system and, more specifically, methods and an apparatus for performing therapeutic apheresis. The present disclosure provides highly efficient methods for therapeutic apheresis that modulate the immune system, thereby resulting in treatment of one or more underlying immunological disease processes. In some embodiments, the disclosed methods return at least a portion of blood from an extracorporeal circuit to a patient in pulsatile flow, where the portion of blood that is returned is augmented. In other embodiments, the disclosed methods and apparatus use the central arterial system to exchange volumes of plasma to immunomodulate disease processes. The disclosed methods combine concepts of intermittent flow and continuous flow therapeutic apheresis with established cardiovascular concepts. In addition, the disclosed methods reduce the amount of time spent by patients in therapeutic apheresis sessions and decrease patients' dependence on immunological drugs that may have detrimental adverse effects.

An intravenous fluid conditioning system includes a housing having a first chamber and a second chamber. A volume of heat transfer medium is located in the first chamber and the second chamber. A first intravenous fluid line extends through the first chamber and a second intravenous fluid line extends through the second chamber. One or more thermoelectric devices are located in the housing, such that a first side of each of the one or more thermoelectric devices is in thermal communication with the first chamber and a second side of each of the one or more thermoelectric devices opposite the first side is in thermal communication with the second chamber. The one or more thermoelectric devices exchange thermal energy with a volume of intravenous fluid selectably flowed through the first intravenous fluid line or the second intravenous fluid line to condition the intravenous fluid.

A sensor including electrodes, a control module and a physical layer module. The electrodes are configured to (i) attach to a patient, and (ii) receive a first electromyographic signal from the patient. The control module is connected to the electrodes. The control module is configured to (i) detect the first electromyographic signal, and (ii) generate a first voltage signal. The physical layer module is configured to: receive a payload request from a console interface module or a nerve integrity monitoring device; and based on the payload request, (i) upconvert the first voltage signal to a first radio frequency signal, and (ii) wirelessly transmit the first radio frequency signal from the sensor to the console interface module or the nerve integrity monitoring device.

A medical treatment system, such as a peritoneal dialysis system, may include a control system and other features to enhance patient comfort and ease of use. For example, the peritoneal dialysis system may include the control system that can adjust a volume of fluid infused into a peritoneal cavity to prevent an intraperitoneal fluid volume from exceeding a pre-determined amount. The control system can adjust by adding one or more therapy cycles, allowing for fill volumes during each cycle of the one or more therapy cycles to be reduced. The control system may continue to allow the fluid to drain from the peritoneal cavity as completely as possible before starting the next therapy cycle of the one or more therapy cycles. The control system may also adjust a dwell time of the fluid within the peritoneal cavity during the one or more therapy cycles in order to complete a therapy within a scheduled time period. A cycler may also be configured to have a heater control system that monitors both a temperature of a heating tray and a temperature of a bag of dialysis fluid in order to bring a temperature of the dialysis fluid rapidly to a specified temperature, with minimal temperature overshoot.

Methods and systems are provided for delivering anesthetic agent to a patient. In one embodiment, an anesthetic vaporizer includes a sump configured to hold a liquid anesthetic agent; an ultrasonic transducer coupled to a bottom of the sump and at least partially disposed within the sump; a vaporizing chamber fluidically coupled to the sump; and a heating element coupled to the vaporizing chamber and configured to increase a temperature of a surface disposed within the vaporizing chamber.

Temperature-controlled mattress control system and method based on sleep posture detection are provided. The control system includes an information collecting unit, an information processor and an output instruction unit. The information collecting unit is used to collect a temperature parameter of a human body during sleeping, video information, and a temperature parameter of a temperature-controlled mattress. The information processing unit receives information collected by the information collecting unit, calculates a sleep posture value K, a thermal sensation value P and a facial skin thermal value Q to obtain a final estimated thermal sensation, and determines setting temperature variation of the temperature-controlled mattress based on the temperature parameter of the temperature-controlled mattress. The output instruction unit receives the setting temperature variation and the temperature parameter of the temperature-controlled mattress, and issues an instruction to a water chiller-heater unit to enable the water chiller-heater unit to carry out fluid temperature regulation.

A respiratory treatment device includes a blower for providing flow of breathable gas to a patient and one or more accessory devices. The respiratory treatment device includes active power management to distribute power from a power source that does not have sufficient power to simultaneously power the blower and the accessory devices. The active power management prioritizes power to the blower and limits, based on current measurements of the blower and the accessory devices, the power supplied to the accessory devices to keep the sum of the power drawn at or below the capacity of the power supply. When additional power is available, due reduced power consumption of the blower, the power to one or more accessory devices is raised beyond a target in order to compensate for when power was not supplied to the one or more accessory devices.

A catheter assembly may include a catheter adapter, which may include a distal end, a proximal end, and a lumen extending through the distal end and the proximal end of the catheter adapter. The catheter assembly may also include a catheter extending from the distal end of the catheter adapter. The distal tip of the catheter may include a magnetic material. A method of repositioning the distal tip of the catheter may include inserting the distal tip of the catheter into a blood vessel. The method may include attaching another magnetic material to skin, and the distal tip of the catheter may move toward the other magnetic material. At least one of the magnetic material and the other magnetic material may include a magnet. A kit may include the catheter assembly and/or the other magnetic material.

An extracorporeal blood treatment apparatus comprises: a blood treatment device (2); an extracorporeal blood circuit comprising a blood withdrawal line (6) and a blood return line (7) coupled to the extracorporeal blood treatment device (2), wherein the blood return line (7) presents a heating zone (14) coupled or configured to be coupled to a blood warmer (15); a blood pump (6) configured to be coupled to a pump section of the blood withdrawal line (6); at least a post-infusion line (13, 13′) connected to the blood return line (7) upstream of the heating zone (14); an air trapping device (9) placed on the blood return line (7) upstream of the heating zone (14).