Disclosed is a mask-free system and method for inducing anesthesia in a pediatric patient. In a preferred embodiment, calming and then anesthetic gases are administered through a mouthpiece with a distraction device, such as an inflatable bag or balloon or an audible siren whistle. This system avoids the anxieties and trauma of the pediatric patient and their parents that have been associated with mask-based induction methods.

The disclosure relates to a drug delivery device including a plunger disposed within a case and an audible indicator that comprises a resilient element. Thee plunger is slidable from a proximal position to a distal position within the case and the resilient element is in a first configuration when the plunger is in the proximal position, such that the resilient element is deflected radially outwards to a second configuration during movement of the plunger from the proximal position towards the distal position. The resilient element moves from the second configuration towards the first configuration when the plunger moves towards or reaches the distal position, thereby generating an audible and tactile signal.

The disclosure relates to a drug delivery device comprising a case adapted to hold a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament (M) from the medicament container, an audible indicator that is arranged within a case pocket lateral to the plunger and that is in operative connection with the plunger, the audible indicator comprises at least one indicator spring and at least one locking element, wherein the indicator spring is biased by the locking element, and the indicator spring relaxes due to a release of the locking element by a movement of the plunger.

An auto-injector having a body (1) receiving a reservoir (S) and including a piston (P); a piston rod (5) movable between a primed position and an injection position in which the piston rod (5) has moved the piston (P) to inject fluid into an injection site; and a visual, audible, and/or tactile indicator device for indicating that the autoinjector may be removed from the injection site. The autoinjector includes a retarding system to delay actuating the indicator device relative to the end of injection and that includes a dashpot (16), a shear member (19) and a fluid. The dashpot or the shear member is rotatably mounted in the body and the other is stationary in rotation, the turning of one relative to the other being braked by shearing the fluid contained in the dashpot. The dashpot and shear member include projections that impede the flow of the fluid.

Methods, systems, computer-readable media, and apparatuses for determining a property of airflow delivered to a user of a medical inhalation device are disclosed.

An inhaler device for pulmonary delivery of at least one substance from a drug dose cartridge to an inhaling user, including: a first conduit for conducting a carrier airflow to a proximal opening of a mouthpiece for use by the user; a holder configured to position the dose cartridge within the carrier airflow; and a second conduit for conducting a shunting airflow to the mouthpiece without passing through the dose cartridge position. A controller connected to a valve controls a rate of carrier airflow, for example by controlling the shunting airflow, based on a sensor indication of airflow rate and a target airflow profile.

The disclosure relates to an audible indicator for use with a drug delivery device comprising a bistable resilient force member capable of residing in two states. In a biased state, the resilient force member is biased and stores energy In a relaxed state, the resilient force member is relaxed. The resilient force member releases the stored energy when transitioning from the biased state into the relaxed state, thereby generating an audible signal.

The disclosure relates to a drug delivery device, comprising a mechanical audible indicator capable of producing an audible signal with a volume of at least 100 dB.

The disclosure relates to an audible indicator in combination with a drug delivery device having a resilient force member capable of resting in either of two states. In a biased state, the resilient force member is biased and stores energy and in a relaxed state, the resilient force member is relaxed. The resilient force member releases the stored energy when changing from the biased state into the relaxed state, thereby generating an audible signal, wherein the resilient force member is supported by a retaining element in the biased state in order to prevent transition into the relaxed state.

In some embodiments, a method includes producing, from an adapter, a first wireless signal characterized by a first communication mode with a computing device when a portion of at least one of a medicament delivery device or a simulated medicament delivery is disposed within the adapter. An indication is received when the portion of the medicament delivery device or the simulated medicament delivery device is removed from the adapter. A second wireless signal characterized by a second communication mode with the computing device is produced in response to the indication. The second communication mode is different from the first communication mode. The second communication mode can be, for example, a hold mode, a sniff mode or a park mode.