An inhaler or add-on device for an inhaler for dispensing a medicament to be inhaled. The inhaler or add-on device has a housing (H) with an air inlet (A_I), and an air outlet (A_O) for outputting air to be inhaled by a user. The housing (H) defines a flow path (FP) between the air inlet (A_I) and air outlet (A_O), and a passive acoustic element (PAE) is arranged in this flow path (FP) inside the housing (H). The passive acoustic element (PAE) has a structure having one or more structured gaps arranged to be passed by an air flow and it is dimensioned such that air flow passing it will generate sound (S) with pre-determined characteristics depending on the air flow speed. This allows acoustic monitoring of air flow passing the first passive acoustic element (PAE) external to the housing (H) by capturing and processing sound generated.

The present invention provides a spacer device having a flow rate spirometer. The flow rate indicator allows users to use a measured, consistent flow rate leading to improved synchronicity and actuation.

A delivery device for use in administering a dry powder to a biological subject's airway is provided. The device comprises (a) a housing having an inlet in fluid communication with an outlet for delivering a flow of gas to the subject's airway; and (b) one or more cantilever structures located within the housing. Vibration of the one or more cantilever structures facilitates entry of the dry powder into the flow of gas, such that the dry powder can be delivered by the flow of gas through the outlet to the subject's airway. Also provided is a container for releasably storing a particulate composition, the container comprising a shell sealed by a seal in which the particulate composition is stored, wherein a puncturing device for rupturing the seal to release the particulate composition is housed within the shell. Further provided are associated methods for administering dry powder using the delivery device and/or container.

An example aerosol delivery device includes a mouthpiece having an airflow outlet, and an airflow passage extending between an airflow inlet and the airflow outlet. The example aerosol delivery device further includes a housing configured to receive a cartridge that includes an aerosolizable substance and a vapor element configured to heat the aerosolizable substance, and an internal power source configured to provide electrical power. The example aerosol delivery device further includes a controller coupled to the internal power source to receive a portion of the electrical power and configured to, when the cartridge is installed at the housing, cause the vapor element of the cartridge to heat the aerosolizable substance to release an aerosol into the airflow passage during an inhalation through the airflow outlet, and a connector configured to receive power from an external source to recharge the internal power source.

A warning system for use with an inhaler includes an operating mechanism that is configured to be actuated to a reset state, a primed state, and a fired state. The inhaler dispenses a metered dose of a medicament upon actuation of the operating mechanism from the primed state to the fired state. The warning system includes a control circuit that is activated upon actuation of the operating mechanism from the primed state to the fired state. The warning system also includes an alert device communicably coupled to the control circuit and configured to generate a warning. Further, the control circuit is configured to control the alert device to generate the warning until the operating mechanism has been actuated from the fired state to the reset state.

A system for use with an inhaler includes an actuator housing. The system includes a loudspeaker disposed within the actuator housing. The loudspeaker is configured to emit an acoustic pulse during use of the inhaler by a patient. The system also includes a microphone disposed within the actuator housing. The microphone is configured to receive reflected sound generated in response to the acoustic pulse. The system further includes a controller communicably coupled to the microphone. The controller is configured to determine a parameter of the oral cavity of the patient based on the reflected sound.

An audible indicator for use with a drug delivery device is described. The audible indicator includes a spring element configured to reside in one of a relaxed state or a biased state. The audible indicator includes a rotatable element coupled to the spring element. The spring element releases stored energy to rotate the rotatable element such that the rotatable element impacts a surface to generate an audible signal when the spring element changes from the biased state into the relaxed state.

The disclosure relates to a drug delivery device, comprising a mechanical audible indicator capable of producing an audible signal with a volume of at least 100 dB.

An automatic injection device includes an injection syringe for injecting liquid provided with a syringe body carrying an injection needle and a piston rod mounted to be able to move inside this syringe body to cover an injection stroke during which the liquid is injected, an external casing and a positioning control member that are telescopic, the relative movement of which controls the operation of the automatic injection device, and control members arranged to selectively control the movement of the syringe body and the movement of the piston inside the positioning control member in order to automatically inject the liquid present in the injection syringe, the automatic injection device further comprising a device for generating sound signals activated during the automatic injection of the liquid present in the injection syringe so as to generate a series of sound signals from the start to the end of the injection.

An aerosol-generating system comprising: an aerosol-generating article (1), the aerosol-generating article comprising a single metered dose of an aerosol-forming substrate; an airflow pathway (108) arranged between an air inlet (110) and an air outlet (112); an aerosolisation chamber (116) arranged at a location along the airflow pathway (108) such that the airflow pathway passes through at least a portion of the aerosolisation chamber (116); and a flow controller (122, 124) for selectively controlling the flow of air through the airflow pathway (108), the flow controller (122, 124) having an open configuration in which air can flow into and out of the aerosolisation chamber (116) and a closed configuration in which air is substantially prevented from flowing into and out of the aerosolisation chamber (116); wherein the aerosolisation chamber (116) is configured to open to receive only one aerosol-generating article (1) at a time; wherein the aerosolisation chamber (116) is configured to close to contain the aerosol-generating article (1); the aerosol-generating system further comprising a heating element (118, 120) arranged to heat the aerosolisation chamber (116) when an aerosol-generating article (1) is received within the aerosolisation chamber (116); wherein the aerosol-generating system is configured to heat the aerosolisation chamber (116) containing the aerosol-generating article (1) only when the flow controller (122, 124) is in the closed configuration.