The disclosure relates to an audible indicator in combination with a drug delivery device having a resilient force member capable of resting in either of two states. In a biased state, the resilient force member is biased and stores energy and in a relaxed state, the resilient force member is relaxed. The resilient force member releases the stored energy when changing from the biased state into the relaxed state, thereby generating an audible signal, wherein the resilient force member is supported by a retaining element in the biased state in order to prevent transition into the relaxed state.

An automatic medicament delivery device for auto injections that has a re-usable part containing a driving and a signal mechanism and a disposable part containing a syringe or a cartridge with a medicament. The parts can be interconnected simply in one axial move avoiding any rotation or turning. The device is easily and safely connected from two parts prior and during the injection process and automatically dissembled when the injection is completed allowing to remove the disposable part.

The present disclosure relates to a feedback mechanism for a drug delivery device, the feedback mechanism comprising a bushing, the bushing comprising a central aperture adapted to accommodate a piston rod, wherein one or more resilient flaps are provided on the bushing, the flaps extending into the central aperture to allow them to engage one or more transversal ribs on the piston rod.

A system for measuring injection of a liquid medicine includes a syringe body having proximal and distal ends, a syringe interior, and a syringe flange at the proximal end thereof. The system also includes a stopper member disposed in the syringe interior. The system further includes a plunger member coupled to the stopper member and configured to be manipulated to insert the stopper member distally in the syringe interior relative to the syringe body. Moreover, the system includes a needle coupled to the syringe body at the distal end thereof. In addition, the system includes a sensor flange removably coupled to a syringe body. The sensor flange includes a sensor to measure an injection characteristic and a processor to analyze the injection characteristic to determine an occurrence of an injection event.

A tubing assembly for use with electronic catheter guidance systems is provided and includes a catheter and an acoustic sensor. The catheter extends in a longitudinal direction and has a proximal end and a distal end that define a lumen therebetween. Further, the catheter is configured for placement within a patient's digestive tract. The acoustic sensor can be located within the lumen of the catheter or in a sampling chamber connected to the catheter. The acoustic sensor can communicate with a processor to deliver sound data to a display device. The appearance of random spikes on a frequency versus time spectrogram can indicate placement of the catheter in the digestive tract, while a rhythmic/repetitive pattern on a frequency versus time spectrogram can indicate placement of the catheter in the respiratory tract. A catheter guidance system and method for accurately placing a catheter in the digestive tract are also provided.

A device for injecting a medicament is provided. The device has a housing with a container within it which can hold a medicament. At its proximal end the container has a needle and a stopper. The device includes a plunger which at one end can engage the stopper. At the opposite end, the plunger can engage a first resilient member to move the stopper within the container to inject the medicament from the container. The device includes a collar with distal and proximal ends, the distal end engaging with a carriage and causing its rotation and the proximal end engaging with a second resilient member. The second resilient member can engage with a skin sensor which has distal and proximal ends. At the proximal end, the skin sensor can contact an injection site. The housing has a cap which can reduce or prevent movement of the skin sensor.

A drug delivery device comprising a case adapted to hold a medicament container, a plunger disposed within the case and slidable from a proximal position into a distal position for delivering a medicament from the medicament container, an audible indicator that is arranged within a case pocket lateral to the plunger and that is in operative connection with the plunger, the audible indicator comprises at least one indicator spring and at least one locking element. The indicator spring is biased by the locking element, and the indicator spring relaxes due to a release of the locking element by a movement of the plunger.

An acoustic device for spirometric measurement is provided. The acoustic device includes an inlet conduit configured to receive an airflow and a central cavity in communication with the inlet conduit. The central cavity includes a channel configured to guide at least a portion of the airflow into a vorticial flow about a central axis of the central cavity. The acoustic device further includes an outlet conduit configured to receive at least a portion of the vorticial flow and transduce at least a portion of kinetic energy of the vorticial flow into an acoustic emission. A frequency of the acoustic emission varies based on a rate of the airflow provided to the inlet conduit. In addition, the acoustic device includes a flow controller configured to modify at least a portion of the airflow provided to the inlet conduit.

The present disclosure relates to systems, apparatuses, and methods for assembling cartridges for aerosol delivery devices. The cartridges may be assembled by transporting carriages between various substations at which parts are added to a base. In another assembly method, the base may be moved between a plurality of robots which direct the base downwardly into contact with components to couple the components therewith. An inspection system may inspect the cartridges at various stages of completion.

A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.