An overdose of opioids can cause the user to stop breathing, resulting in death. A physiological monitoring system monitors respiration based on oxygen saturation readings from a fingertip pulse oximeter in communication with a smart mobile device and sends opioid monitoring information from the smart mobile device to an opioid overdose monitoring service. The opioid overdose monitoring service notifies a first set of contacts when the opioid monitoring information.

A blood pressure prediction method and an electronic device using the same are provided. The method includes the following steps. A training data set is collected. A first blood pressure prediction model is established according to the training data set. Hemodialysis parameter data of a target patient is received, wherein the hemodialysis parameter data includes a first hemodialysis parameter at a previous time point and a second hemodialysis parameter at a current time point. A hemodialysis parameter variation amount between the first hemodialysis parameter and the second hemodialysis parameter is calculated. The hemodialysis parameter variation amount is provided to the first blood pressure prediction model to generate a prediction blood pressure variation associated with a next time point. An operation is performed according to the prediction blood pressure variation of the target patient.

Magnetic-based electronic valve readers for determining a location and orientation of magnets coupled to implantable medical devices to determine a setting of the device (e.g., setting of a fluid flow control valve of the medical device). The electronic valve readers include an orientation sensing mechanism that is provided and configured to enable the electronic valve reader to: 1) allow for internal offset calculation of an orientation change of the electronic valve reader during a reading process; and/or 2) during the reading process, provide an indication or warning to the clinician that the orientation of the electronic valve reader has changed to an extent at or exceeding a predetermined angular acceptance threshold or window. Systems including the disclosed electronic valve readers and methods of reading a setting of the device are also disclosed.

Disclosed are methods and medical device systems for automated delivery of therapies for pain and determination of need for and safety of treatment. In one embodiment, such a medical device system may comprise a sensor configured to sense at least one body signal from a patient; and a medical device configured to receive a first sensed body signal from the sensor; determine a patient pain index based at least in part on said first sensed body signal; determine whether said patient pain index is above at least a first pain index threshold; determine a safety index based at least in part on a second sensed body signal; select a pain treatment regimen based on at least one of said safety index and or a determination that said pain index is above said first pain index threshold; and deliver said pain treatment regimen.

An autoinjector includes a housing, a product container, a torsion spring, a drive element, and a propulsion element. In order to discharge liquid out of the product container, the torsion spring rotates the drive element, and the rotating drive element produces a propulsive movement of the propulsion element and of a piston in the product container. A rotation sensor is configured for an alternating continuous detection of at least two rotational positions per revolution of the drive element during the discharge process, and a processor unit is configured for determining the axial position of the piston in the product container from the detected rotational positions.

An electronic module is configured for attachment to a proximal end of a drug delivery device in a predefined fastening configuration. The drug delivery device comprises an elongated housing extending in a longitudinal direction and comprising a distal end and the proximal end. The electronic module comprises a mechanical coding comprising a mechanical coding feature to engage with a mechanical counter coding feature of a mechanical counter coding provided at the proximal end of the drug delivery device, wherein one of the mechanical coding feature and the mechanical counter coding feature comprises a protrusion extending in the longitudinal direction and wherein the other one of the mechanical coding feature and the mechanical counter coding feature comprises a recess, wherein, in some configurations, the mechanical coding and the mechanical counter coding are operable to prevent a fastening of the electronic module to the drug delivery device.

A device is disclosed that is configured as a fully autonomous and integrated wearable apparatus for diabetes management. The device comprise a self-pressurized reservoir for storing the medication for subsequent delivery to a patient, a needle for delivering the medication to the patient subcutaneously, a first MEMS device configured as a microvalve in a fluid path between the self-pressurized reservoir and needle for controlling flowrate of medication through the needle as the self-pressurized reservoir discharges, a second MEMS device configured as a micropump configured to increase flowrate of the medication in the fluid path to ensure a constant flowrate in the fluid path as the self-pressurized discharges independent of orientation of the device, a flow sensor configured to measure flowrate in the fluid path for controlling microvalve and micropump, and control circuitry connected to the microvalve, micropump and flow sensor for controlling operation of the micropump and microvalve.

An injection system can have a Syringe Dose and Position Apparatus (SDPA) mounted to a syringe. The SDPA can have one or more circuit boards. The SDPA can include one or more sensors for determining information about an injection procedure, such as the dose measurement, injection location, and the like. The SDPA can also include a power management board, which can be a separate board than a board mounted with the sensors. The syringe can also include a light source in the needle. Light emitted from the light source can be detected by light detectors inside a training apparatus configured to receive the injection. The syringe can have a power source for powering the sensors and the light source. The SDPA and the power source can be mounted to the syringe flange.

A sensing module for monitoring dosage delivery of a vaporized material, and a portable vaporization unit including the sensing module, include a light sensor that detects disruptions in a light path across a vapor channel, the disruptions caused by the vaporized material flowing through the vapor channel. The light sensor includes a UV light source, which may emit 370 nm wavelength light, and a UV light detector that converts intensity of incident light in the light path into a signal. A microprocessor of the sensing module compares the signal to a baseline measurement to determine the concentration of a medicament in the vapor; then, using the flow rate and activation time of the device, the microprocessor determines the dosage and can perform monitoring and reporting actions based on the dosage. A measuring circuit measures fluctuations in resistance/impedance of a vaporization element to further determine flow rate and/or dosage.

An intravenous therapy system may include a hollow needle comprising a distal end and a proximal end, the distal end comprising a sharp tip for insertion into a vein; an infrared (IR) camera placed within a hollow portion of the hollow needle, including: an IR detector; a first light source to emit a first wavelength of IR light; and a second light source to emit a second wavelength of IR light; a comparator to, upon execution of a processor communicatively coupled to the comparator, compare an amount of reflected light received at the IR detector during activation of the first light and second light and provide an indication of light absorption within a vein.