The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.

A method of forming a material includes presenting a formable material to a space between opposing forming surfaces of opposed forming tools from whence said material is carried as said opposing forming surfaces advance in a machine direction. The method includes pressurising, as said opposing forming surfaces advance, said material between said opposing forming surfaces in a reduced space between said opposing forming surfaces defining at least in part a pressure forming zone, said reduced space between said opposing forming surfaces being maintained constant until a form of at least one of said opposing forming surfaces is profiled into said material and is retainable thereon. The method also includes releasing the profiled material from between the said opposing forming surfaces, as the space of the pressure forming zone increases between said opposing forming surfaces as the opposing forming surfaces advance.

A method of forming a material includes presenting a formable material to a space between opposing forming surfaces of opposed forming tools from whence said material is carried as said opposing forming surfaces advance in a machine direction. The method includes pressurising, as said opposing forming surfaces advance, said material between said opposing forming surfaces in a reduced space between said opposing forming surfaces defining at least in part a pressure forming zone, said reduced space between said opposing forming surfaces being maintained constant until a form of at least one of said opposing forming surfaces is profiled into said material and is retainable thereon. The method also includes releasing the profiled material from between the said opposing forming surfaces, as the space of the pressure forming zone increases between said opposing forming surfaces as the opposing forming surfaces advance.

A system for the continuous extrusion, molding, and curing of tread rubber is provided. A plurality of discrete mold sectors are arranged adjacent to each other along a longitudinal axis between an in-feed and an out-feed of a mold sector transport mechanism that extends through a heated press. As the mold sectors are continuously advanced along a process direction in steps, rubber material is extruded and placed onto at least one of the mold sectors near the in-feed end such that an elongated strip of rubber material extends over multiple mold sectors along the longitudinal axis. As the strip of rubber material exits the press, the mold sectors are sequentially removed from the rubber material and returned to the in-feed. An extruder outlet positioned near the in-feed can be moved towards or away from the mold sectors to supply rubber material and prevent backflow.

A system for the continuous extrusion, molding, and curing of tread rubber is provided. A plurality of discrete mold sectors are arranged adjacent to each other along a longitudinal axis between an in-feed and an out-feed of a mold sector transport mechanism that extends through a heated press. As the mold sectors are continuously advanced along a process direction in steps, rubber material is extruded and placed onto at least one of the mold sectors near the in-feed end such that an elongated strip of rubber material extends over multiple mold sectors along the longitudinal axis. As the strip of rubber material exits the press, the mold sectors are sequentially removed from the rubber material and returned to the in-feed. An extruder outlet positioned near the in-feed can be moved towards or away from the mold sectors to supply rubber material and prevent backflow.

The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.

A method of forming a material includes presenting a formable material to a space between opposing forming surfaces of opposed forming tools from whence said material is carried as said opposing forming surfaces advance in a machine direction. The method includes pressurising, as said opposing forming surfaces advance, said material between said opposing forming surfaces in a reduced space between said opposing forming surfaces defining at least in part a pressure forming zone, said reduced space between said opposing forming surfaces being maintained constant until a form of at least one of said opposing forming surfaces is profiled into said material and is retainable thereon. The method also includes releasing the profiled material from between the said opposing forming surfaces, as the space of the pressure forming zone increases between said opposing forming surfaces as the opposing forming surfaces advance.

A method of forming a material includes presenting a formable material to a space between opposing forming surfaces of opposed forming tools from whence said material is carried as said opposing forming surfaces advance in a machine direction. The method includes pressurising, as said opposing forming surfaces advance, said material between said opposing forming surfaces in a reduced space between said opposing forming surfaces defining at least in part a pressure forming zone, said reduced space between said opposing forming surfaces being maintained constant until a form of at least one of said opposing forming surfaces is profiled into said material and is retainable thereon. The method also includes releasing the profiled material from between the said opposing forming surfaces, as the space of the pressure forming zone increases between said opposing forming surfaces as the opposing forming surfaces advance.

The present disclosure relates to an oral, immediate release, abuse deterrent pill containing at least one active pharmaceutical ingredient susceptible to abuse which is homogenously spread throughout a carrier matrix used to deter abuse. The pill is prepared using hot melt extrusion and a forming unit through a continuous process. The formed pill is abuse deterrent to parenteral administration due at least to particle size, viscosity, or purity limitations.

A system for continuously processing pulverulent products includes at least two system inlets for pulverulent products. A mixer is provided that continuously mixes the pulverulent products received at a mixer inlet into a product mixture that is dispensed at a mixer outlet. A production machine having a filling apparatus continuously processes the product mixture from the mixer outlet into end products dispensed at the machine outlet. A conveyor apparatus conveys the product mixture from the mixer outlet to the machine inlet. The conveyor apparatus includes a first fill level sensor that measures a product mixture fill level in the filling apparatus of the production machine and a second fill level measures a product mixture fill level in a conveyor reservoir. A control apparatus receives measurement data from the first fill level sensor and the second fill level sensor and controls at least one production parameter based on the measurement data.