Infusion systems, infusion devices, and related operating methods are provided. An exemplary method of operating an infusion device capable of delivering fluid to a user involves storing alert configuration information for the user, identifying an alert condition while operating the infusion device to deliver the fluid based at least in part on the alert configuration information for the user, and in response to identifying the alert condition, providing a user notification in accordance with the user's stored alert configuration information.

A filling aid. The filling aid includes a needle housing portion including at least one tab having a starting position and a filling position, and a filling needle cradle including a filling needle, the filling needle cradle slidable connected to the needle housing portion and having a starting position and a filling position, wherein when the at least one tab on the needle housing moves from a starting position to a filling position, the filling needle cradle slides from a starting position to a filling position, and wherein when the at least one tab on the needle housing moves from a filling position to a starting position, the filling needle cradle slides from a filling position to a starting position.

A switch-operated therapeutic agent delivery device. Embodiments of the operated therapeutic agent delivery device my include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test. The switch operated therapeutic agent delivery device may have two parts, which are assembled by a user prior to use. These devices may be configured to determine if a current is present between the anode and cathode when drug is not intended to be delivered by the device. These devices may indirectly control and/or monitor the applied current without directly measuring from the cathode of the patient terminal.

In some embodiments, a negative pressure apparatus includes a negative pressure source configured to provide negative pressure via a fluid flow path to a wound dressing placed to create a seal over a wound, a pressure sensor, and a controller. The controller can be configured to operate the negative pressure source in a first mode and determine a change in pressure in the fluid flow path over a period of time based on a plurality of measurements by the pressure sensor. In response to a determination that pressure in the fluid flow path is decreasing, the controller can operate the negative pressure source in a second mode in which greater amount of negative pressure is provided than in the first mode. In response to a determination that pressure in the fluid flow path is not decreasing, the controller can provide an indication of a first leak in the seal.

A drug delivery system comprising a controller adapted to detect when a given user-actuated operation being part of the expelling of an amount of drug is performed, record detected operations as a function of time, and estimate, based on recorded operations, time parameters for the detected operations, thereby providing time parameters for a medical regimen on which the detected operations are assumed to be based upon.

A switch-operated therapeutic agent delivery device is described. Embodiments of the operated therapeutic agent delivery device include a switch that can be operated by a user, a device controller connected to the switch through a switch input where the device can actuate the device when certain predetermined conditions are met, following performance of both a digital switch validation test and an analog switch validation test.

A removable gas sensor module is provided for a therapeutic gas delivery device. The gas sensor module includes a sample chamber which receives a sample gas from the therapeutic gas delivery device. A gas detection unit includes a plurality of sensors operable to measure at least one property of the sample gas. The sensors include two or more of a gas detection sensor, a humidity sensor, a temperature sensor, or a combination thereof. The gas sensor module is self-contained within the therapeutic gas delivery device and swappable with another gas sensor module.

The invention relates to a method and to a device for determining an optimum dialysate flow Q.sub.dopt for an extracorporeal blood treatment and to a blood treatment device comprising a device 18 for determining an optimum dialysate flow Qd.sub.opt. The optimum dialysate flow Qd.sub.opt is determined on the basis of a relationship describing the dependence of the clearance K on the dialysate flow Q.sub.d. The device according to the invention comprises a measurement device 18B for measuring at least one value which is characteristic of the clearance K, a calculation and/or evaluation unit 18A of the device according to the invention being configured in such a way that the clearance K is determined on the basis of the at least one value which is characteristic of the clearance. The calculation and/or evaluation unit 18A is configured in such a way that the optimum dialysate flow Q.sub.dopt is determined from the relationship describing the dependence of the clearance K on the dialysate rate Q.sub.d on the basis of the measured clearance K, or the optimum dialysate flow Q.sub.dopt is determined from the measured clearance K.

Disclosed is an infusion pump which may include a native pumping mechanism to drive fluids through a functionally associated conduit, at least one native sensor to sense a physical characteristic of the fluid within the conduit and computing circuitry having a decalibration test mode to determine whether the infusion pump is decalibrated. The computing circuitry may be adapted to receive output from at least one native sensor during the decalibration test mode.

The present disclosure pertains to a method and system configured to in-exsufflate a subject by controlling the in-exsufflation pressure waveform. In some embodiments, the system comprises a pressure generator, a subject interface, one or more sensors, one or more processors, electronic storage, a user interface, and/or other components. The system is configured to assist the subject to loosen and/or expel secretions by inducing a percussive pressure waveform delivered to the subject during inhalation and/or exhalation. The system is configured to control the in-exsufflation therapy delivered to the subject without requiring regular manual setting and/or adjustment of pressures, pressure amplitudes, a frequency range, and/or other parameters of the percussive pressure waveform.